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Lethal(3)malignant brain tumor-like protein 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
(5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanoneIC504200.0 [1], 6000.0 [2], 7900.0 [3], 21000.0 [4]
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)IC502300.0 [1], 8900.0 [2]
1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)IC5010000.0 [1], 170000.0 [2]
UNC 926 hydrochlorideIC503900.0 [1], 4700.0 [2]
(3-Bromophenyl)-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5030000.0 [1]
(3-Bromophenyl)-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5020600.0 [1], 23600.0 [2]
ChlorpheniramineIC5041000.0 [1]
OxybutyninIC50100000.0 [1]
MaprotilineIC5061000.0 [1]
BifemelaneIC5091000.0 [1]
I-OMe-Tyrphostin AG 538IC50282.0 [1]
Cefsulodin sodium saltIC5098.0 [1]
4-Methyl-N-[3-(1-pyrrolidinyl)propyl]benzenesulfonamideIC5017000.0 [1]
6-Bromo-3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-4-hydroxy-2-oxo-1H-quinazoline-4-carboxamideIC5052000.0 [1]
N,N-Dimethyl-4-(1-methyl-9H-pyrido[3,4-b]indol-4-yl)butan-1-amineIC5021000.0 [1]
1-(N-Methylamino)-4-phenylbutaneIC5068000.0 [1]
1,4-Bis(4-(pyrrolidinyl)piperidinyl)benzamideIC502900.0 [1]
4-(2-Methoxy-4-methylphenoxy)-N-methylbutan-1-amineIC50100000.0 [1]
4-(4-Chloro-3-ethylphenoxy)-N-methylbutan-1-amineIC5096000.0 [1]
4-(4-Benzylphenoxy)-N-methylbutan-1-amineIC5091000.0 [1]
1-(1-(4-Chlorophenethyl)piperidin-4-yl)-N-methylmethanamineIC5069000.0 [1]
1-(7-Bromo-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)-3-(dimethylamino)propan-1-oneIC50100000.0 [1]
2-Isopropyl-5-(methylamino)-2-o-tolylpentanenitrileIC5018000.0 [1]
3-Chloro-N-(3-(diethylamino)propyl)-4-fluorobenzenesulfonamideIC50100000.0 [1]
5-Bromo-N-(5-(pyrrolidin-1-YL)pentyl)nicotinamideIC5046000.0 [1]
2-(3-(4-Chlorophenyl)isochroman-1-yl)-N-methylethanamineIC50100000.0 [1]
3-(11h-Dibenzo[b,f][1,4]oxathiepin-11-yl)-n-methylpropan-1-amineIC5014000.0 [1]
1-Phenyl-4-pyrrolidin-1-ylpiperidineIC5090000.0 [1]
4-(Dimethylamino)butan-2-yl 5-(1-phenylethyl)furan-2-carboxylateIC5084000.0 [1]
4-(Pyrrolidin-1-Yl)-1-{4-[2-(Pyrrolidin-1-Yl)ethyl]phenyl}piperidineIC5014000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC505000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)furan-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC502300.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)thiophen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC503700.0 [1]
[3-(Benzylamino)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC50740.0 [1]
[3-Benzyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC501700.0 [1]
[3-Phenoxy-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC503000.0 [1]
[3-Phenyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC502000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC504000.0 [1]
2-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC506600.0 [1]
3-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC509600.0 [1]
3-Bromo-N-(2-ethyl-1,3-dihydroisoindol-5-yl)benzamideIC5030000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[3-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC502800.0 [1]
[2-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC503000.0 [1]
[3,4-Bis(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC502200.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylphenyl]methanoneIC503300.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanoneIC501500.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-[(4-pyrrolidin-1-ylpiperidin-1-yl)methyl]phenyl]methanoneIC503800.0 [1]
(4-Piperidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC506800.0 [1]
[4-(Azepan-1-yl)piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC504200.0 [1]
[4-(4-Morpholin-4-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC507100.0 [1]
(4-Cyclohexylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC507200.0 [1]
[4-[4-(1-Methylpyrrolidin-1-ium-1-yl)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC507500.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC505200.0 [1]
(4-Piperidin-4-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC503500.0 [1]
[4-(4-Cyclopentylpiperazine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC507600.0 [1]
[4-[4-(1-Methylpiperidin-4-yl)piperazine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC503300.0 [1]
[4-[1-(4-Methylpiperazin-1-yl)ethyl]piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC504400.0 [1]
(4-Pyrrolidin-1-ylazepan-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC505900.0 [1]
[4-(3-Pyrrolidin-1-ylazetidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC509500.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(3-pyrrolidin-1-ylpyrrolidine-1-carbonyl)phenyl]methanoneIC506500.0 [1]
4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)-N-(3-pyrrolidin-1-ylpropyl)benzamideIC505500.0 [1]
[4-(2,7-Diazaspiro[3.4]octane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC505600.0 [1]
[4-(2,7-Diazaspiro[4.4]nonane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC507100.0 [1]
[4-(2,8-Diazaspiro[4.5]decane-8-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC505000.0 [1]
[4-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC506900.0 [1]
N-(2-Methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-7-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC508400.0 [1]
[4-(4-Pyrrolidin-1-ylazepane-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylazepan-1-yl)methanoneIC508100.0 [1]
[4-[4-(Azetidin-1-yl)piperidine-1-carbonyl]phenyl]-[4-(azetidin-1-yl)piperidin-1-yl]methanoneIC507400.0 [1]
[4-(4-Pyrrolidin-2-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpyrrolidin-2-yl)piperidine-1-carbonyl]phenyl]-[4-(1-methylpyrrolidin-2-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanoneIC5010000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)pyridin-3-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC504500.0 [1]
[3-Nitro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC502700.0 [1]
[3-Amino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC506800.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[2,3,5,6-tetrafluoro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC502900.0 [1]
[2,5-Dimethyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC501200.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-1-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC503100.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)benzamideIC506800.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC506600.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5010700.0 [1]
[3-Bromo-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC502500.0 [1]
7-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-1,4-dioxa-7-azaspiro[4.4]nonaneIC5092000.0 [1]
6-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-2-oxa-6-azaspiro[3.3]heptaneIC5065000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]pyrrolidine-3-carbonitrileIC50128000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azepaneIC5063000.0 [1]
1-[3-Chloro-4-(2-pyrrolidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidineIC5021000.0 [1]
4-Piperidin-1-yl-1-[4-(2-pyrrolidin-1-ylethyl)phenyl]piperidineIC5050000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(3-pyrrolidin-1-ylpropyl)phenyl]piperidineIC5010000.0 [1]
4-Pyrrolidin-1-yl-1-[3-(2-pyrrolidin-1-ylethyl)phenyl]piperidineIC5030000.0 [1]
[3-(Hydroxymethyl)-1-[2-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azetidin-3-yl]methanolIC5060000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(pyrrolidin-1-ylmethyl)phenyl]piperidineIC5057000.0 [1]
1-[[4-(2-Pyrrolidin-1-ylethyl)phenyl]methyl]pyrrolidineIC5051000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]piperidineIC5032000.0 [1]
4-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]morpholineIC50125000.0 [1]
1-[4-[2-(Azetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidineIC5086000.0 [1]
1-[4-[2-(3,3-Difluoroazetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidineIC50152000.0 [1]
1-[4-(2-Piperidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidineIC5050000.0 [1]
4-Pyrrolidin-1-yl-1-[3-(pyrrolidin-1-ylmethyl)phenyl]piperidineIC5045000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lethal(3)malignant brain tumor-like protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/lethal-3-malignant-brain-tumor-like-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Lethal(3)malignant brain tumor-like protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lethal-3-malignant-brain-tumor-like-protein-1-inhibitors-ic50-ki.
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