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Leucine aminopeptidase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
AmastatinKi30.0 [1], 200.0 [2], 220.0 [3], 20000.0 [4]
UbenimexIC5011200.0 [1]
UbenimexKi0.6 [1], 20.0 [2]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R,3S)-3-Amino-2-hydroxy-5-methylhexanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]butanedioic acidKi20000.0 [1], 23000.0 [2], 200000.0 [3]
2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi66.0 [1]
(1-Amino-3-methylbutyl)phosphonic acidKi230.0 [1]
2-Amino-4-methyl-pentanalKi60.0 [1]
(Aminomethyl)phosphonic acidKi1040000.0 [1]
IsoamylamineKi50000000.0 [1]
ApstatinIC50300.0 [1]
(2S)-N-Benzyl-2-[(2S)-2-(2-hydroxyacetyl)pyrrolidine-1-carbonyl]pyrrolidine-1-carboxamideIC50100000.0 [1]
1-Aminoethylphosphonic acidKi240000.0 [1]
Leucine Phosphonic AcidKi230.0 [1]
(1-Amino-2-phenylethyl)phosphonic acidKi420.0 [1]
Bestatin hydrochlorideKi20000.0 [1]
2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(4-hydroxyphenyl)propanoic acidKi67.0 [1]
[(1S)-1-Amino-3-methylbutyl]phosphonic acidKi220000.0 [1]
2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-4-methyl-pentanoic acidKi120.0 [1]
1-Aminopropylphosphonic acidKi3600.0 [1]
3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-butyramideKi510.0 [1]
(S)-4-Methyl-2-[[(2S,3S)-2-hydroxy-3-amino-4-phenylbutanoyl]amino]pentanoic acidKi17000.0 [1]
1-Amino-2-methylpropylphosphonic acidKi1200.0 [1]
CID 10336627IC507800.0 [1]
2-Amino-4-methyl-pentane-1-thiolKi450000.0 [1]
(2s)-3-[(R)-[(1s)-1-Amino-3-Phenylpropyl](Hydroxy)phosphoryl]-2-Benzylpropanoic AcidKi988.0 [1]
D-LeucinolKi1000000.0 [1]
1-Aminohexylphosphonic AcidKi1000.0 [1]
(2s)-3-[(S)-[(1r)-1-Amino-3-Phenylpropyl](Hydroxy)phosphoryl]-2-Benzylpropanoic AcidKi45.0 [1]
(1-Amino-3-methylbutyl)-hydroxy-oxophosphaniumKi87000.0 [1]
(1-Amino-2-phenylethyl)phosphinic acidKi59000.0 [1]
3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid methyl esterIC5050000.0 [1]
3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid benzyl esterIC50100000.0 [1]
2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-4-methylpentanoic acidKi74.0 [1]
(2Z,5S)-4-Oxo-5-amino-7-methyl-2-octenoic acid methyl esterKi76.0 [1]
3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric acid benzyl esterIC5080000.0 [1]
(2S)-1-[(3R,4S)-4-Amino-3-hydroxy-6-methylheptanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC50800000.0 [1]
(2S)-1-[(2S,3S)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC50450000.0 [1]
(2S)-1-[(2S,4R)-1-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-4-hydroxypyrrolidine-2-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC501600.0 [1]
2-[(2S)-2-[[(2S)-1-Amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-phenylbutanoic acidIC501000000.0 [1]
(2S)-1-[(4R)-3-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-1,3-thiazolidine-4-carbonyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC50180.0 [1]
(2S)-1-[(2R,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC501000000.0 [1]
3-[(1-Amino-3-methylbutyl)-hydroxyphosphoryl]propanoic acidKi330.0 [1]
2-[[[(1R)-1-Amino-3-methylbutyl]-hydroxyphosphoryl]methyl]-4-methylpentanoic acidKi65.0 [1]
2-[[(1-Amino-3-methylbutyl)-hydroxyphosphoryl]methyl]-4-methylpentanoic acidKi110.0 [1]
(2S)-1-[(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC5012000.0 [1]
(2S)-1-[(2S)-1-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxamideIC502500.0 [1]
2-Phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethanamineKi50.0 [1]
3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amineKi1300.0 [1]
1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethanamineKi90000.0 [1]
(1-Amino-3-methylbutyl)-methoxyphosphinic acidKi320000.0 [1]
(1-Amino-2-phenylethyl)-methoxyphosphinic acidKi43000.0 [1]
2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyloxy]-4-methyl-pentanoic acidKi58000.0 [1]
(2S)-2-[(1-Amino-3-methylbutyl)-hydroxyphosphoryl]oxy-4-methylpentanoic acidKi58000.0 [1]
(2S)-2-[[(1-Amino-3-methylbutyl)-hydroxyphosphoryl]carbonylamino]-4-methylpentanoic acidKi56000.0 [1]
(2S)-2-[[(1-Amino-3-methylbutyl)-methoxyphosphoryl]carbonylamino]-4-methylpentanoic acidKi1650000.0 [1]
(2S)-2-[[Amino-(1-amino-3-methylbutyl)phosphoryl]carbonylamino]-4-methylpentanoic acidKi40000.0 [1]
3-Methylbutylphosphonic acidKi775000.0 [1]
(R)-3-Amino-2-mercapto-4-phenyl-butyric acid methyl esterKi300000.0 [1]
(2R)-2-[[(1-Amino-3-methylbutyl)-hydroxyphosphoryl]carbonylamino]-4-methylpentanoic acidKi56000.0 [1]
(2S)-2-[[(2S,3R)-3-Amino-4-phenyl-2-sulfanylbutanoyl]amino]-4-methylpentanoic acidKi550.0 [1]
(2S)-2-[[(2S,3R)-3-Amino-4-phenyl-2-sulfanylbutanoyl]amino]-4-methylpentanoic acid;hydrochlorideKi1000.0 [1]
(2R)-2-[[[(1S)-1-Amino-3-phenylpropyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi8800.0 [1]
(1-Aminooctyl)phosphonic acidKi470.0 [1]
[(1R)-1-Amino-2-phenylethyl]phosphonic acidKi420.0 [1]
(2R)-2-[[(1-Amino-2-phenylethyl)-hydroxyphosphoryl]oxymethyl]-4-methylpentanoic acidKi340000.0 [1]
(2R)-2-[[(1-Amino-3-methylbutyl)-hydroxyphosphoryl]oxymethyl]-4-methylpentanoic acidKi58000.0 [1]
(2S)-2-[[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanethioyl]amino]-4-methylpentanoic acid;2,2,2-trifluoroacetic acidKi330.0 [1]
(2S,3R)-3-Amino-2-hydroxy-N-(3-methylbutyl)-4-phenylbutanethioamideKi4400.0 [1]
3-Amino-2-mercapto-N-(3-methyl-butyl)-4-phenyl-butyramideKi26000.0 [1]
(2S,3R)-3-Amino-N-(3-methylbutyl)-4-phenyl-2-sulfanylbutanamideKi167000.0 [1]
3-Amino-5-methyl-hexane-2-thiolKi500000.0 [1]
Methyl (3R)-3-amino-2-hydroxy-4-phenylbutanoateKi33000.0 [1]
2,6-Diamino-hexane-1-thiolKi1000000.0 [1]
3-Amino-5-methyl-hexan-2-olKi507000.0 [1]
(2S)-N-[(2S)-1-Amino-1-oxopropan-2-yl]-1-[2-(hydroxycarbamoyl)cyclohexanecarbonyl]pyrrolidine-2-carboxamideIC501000000.0 [1]
(2S)-N-[(2S)-1-Amino-1-oxopropan-2-yl]-1-(2-sulfanylcyclopentanecarbonyl)pyrrolidine-2-carboxamideIC501000000.0 [1]
(2S)-1-[(2S)-1-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]pyrrolidine-2-carbonyl]-N-[(2S)-1-[[(2S)-1-[[(2R)-1-amino-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]pyrrolidine-2-carboxamideIC50290.0 [1]
2-(3-Amino-2-methyl-4-phenyl-butyrylamino)-4-methyl-pentanoic acidKi3780000.0 [1]
2-[[2-[(3-Amino-2-hydroxy-5-methylhexanoyl)amino]-3-methylbutanoyl]amino]butanedioic acidKi1240.0 [1]
(2R,3S)-3-Amino-2-hydroxy-N-(3-methylbutyl)-4-phenylbutanamideKi500.0 [1]
(2R)-2-[[[(1R)-1-Amino-3-phenylpropyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi271.0 [1]
(1-Amino-3-methylbutyl)-phenoxyphosphinic acidKi230.0 [1]
(1-Amino-2-phenylethyl)-phenoxyphosphinic acidKi420.0 [1]
[(1S)-1-Amino-2-phenylethyl]phosphonic acidKi15400.0 [1]
2-[2-(2-Tert-Butoxycarbonylamino-3-methyl-butyrylamino)-3-methyl-butyrylamino]-succinic acidKi1400000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[(2-Hydroxy-5-methylhexanoyl)amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]butanedioic acid;hydrochlorideKi740000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(3R)-3-Amino-5-methylhexanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]butanedioic acidKi681000.0 [1]
(2R,3S)-3-Amino-2-hydroxy-5-methyl-N-[(2S)-3-methyl-1-[[(2S)-3-methyl-1-(3-methylbutylamino)-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]hexanamideKi890.0 [1]
(3S,4S)-4-Amino-3-hydroxy-6-methyl-N-[(2S)-3-methyl-1-[[(2S)-3-methyl-1-(3-methylbutylamino)-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]heptanamideKi1000000.0 [1]
ThioamineIC5050000.0 [1]
2-[[Hydroxy-(1-hydroxy-3-methylbutyl)phosphoryl]amino]acetic acidKi4880.0 [1]
4-(7-Amino-6-oxo-5,7,8,9-tetrahydrobenzo[7]annulen-4-yl)benzonitrileKi35000.0 [1]
7-Amino-4-(3-nitrophenyl)-5,7,8,9-tetrahydrobenzo[7]annulen-6-oneKi30000.0 [1]
Items per page: 1 - 10 of 93
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References

This online tool may be cited as follows

MLA

"Quest Database™ Leucine aminopeptidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/leucine-aminopeptidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Leucine aminopeptidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/leucine-aminopeptidase-inhibitors-ic50-ki.
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