Name: Leukocyte adhesion glycoprotein LFA-1 alpha Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Leukocyte adhesion glycoprotein LFA-1 alpha Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	5-[[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl]methyl]thiophene-3-carboxylic acid	IC50	18.0 ^[1], 276.0 ^[2], 280.0 ^[3]
	Bms-688521	IC50	2.5 ^[1], 60.0 ^[2], 276.0 ^[3]
	2-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl]pyrimidine-5-carboxylic acid	IC50	11.0 ^[1], 260.0 ^[2]
	5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl]pyrazine-2-carboxylic acid	IC50	19.0 ^[1], 1260.0 ^[2]
	6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl]pyridazine-3-carboxylic acid	IC50	13.0 ^[1], 270.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Leukocyte adhesion glycoprotein LFA-1 alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 2 Oct. 2025, https://www.aatbio.com/data-sets/leukocyte-adhesion-glycoprotein-lfa-1-alpha-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, October 2). Quest Database™ Leukocyte adhesion glycoprotein LFA-1 alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/leukocyte-adhesion-glycoprotein-lfa-1-alpha-inhibitors-ic50-ki.
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