Lymphocyte differentiation antigen CD38 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-Methyl-4-(2-fluoro-6-trifluoromethylbenzylamino)quinoline-8-carboxamide	IC50	510.0 [1]
	1-Methyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	89.0 [1]
	1-Methyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)quinolin-2-one	Ki	14.0 [1]
	CD38 inhibitor 1	IC50	7.3 [1]
	CD38 inhibitor 1	Ki	0.3 [1]
	4-[[4-(2-Methoxyethoxy)cyclohexyl]amino]-1,8-dimethyl-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	10.0 [1]
	4-[[4-(2-Methoxyethoxy)cyclohexyl]amino]-1,8-dimethyl-6-(1,3-thiazol-5-yl)quinolin-2-one	Ki	0.7 [1]
	4-[(4-Methoxycyclohexyl)amino]-1,8-dimethyl-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	15.0 [1]
	4-[(4-Methoxycyclohexyl)amino]-1,8-dimethyl-6-(1,3-thiazol-5-yl)quinolin-2-one	Ki	0.45 [1]
	4-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]cyclohexane-1-carboxylic acid	IC50	498.0 [1], 30200.0 [2]
	1-[4-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]cyclohexyl]pyrrolidin-2-one	IC50	1960.0 [1], 8540.0 [2]
	Quercetin	IC50	37900.0 [1]
	Resveratrol	IC50	100000.0 [1]
	Luteolin	IC50	8200.0 [1]
	Myricetin	IC50	24800.0 [1]
	Cyanidin	IC50	21800.0 [1]
	3,3',4',5,5',7-Hexahydroxyflavylium	IC50	14600.0 [1]
	Piceatannol	IC50	100000.0 [1]
	Cyanidin 3-O-glucoside	IC50	6300.0 [1]
	Fisetinidin	IC50	70300.0 [1]
	Dihydroquercetin	IC50	100000.0 [1]
	Malvidin	IC50	17000.0 [1]
	Pelargonidin	IC50	16300.0 [1]
	6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide	IC50	100000.0 [1]
	Peonidin	IC50	20900.0 [1]
	Petunidin	IC50	39200.0 [1]
	L-Epicatechin	IC50	100000.0 [1]
	Quercetagetin	IC50	48600.0 [1]
	Robinetin	IC50	37900.0 [1]
	6-Methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide	IC50	100000.0 [1]
	2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide	IC50	100000.0 [1]
	2,3,4,9-Tetrahydro-1H-carbazole-1-carboxamide	IC50	100000.0 [1]
	Diosmetinidin	IC50	32100.0 [1]
	6-Hydroxycyanidin	IC50	14200.0 [1]
	(2R,3R,4S,5R,13R,14S,15R,16R)-3,4,8,10,14,15-Hexahydroxy-8,10-dioxo-7,9,11,25,26-pentaoxa-1,17,19,22-tetraza-8lambda5,10lambda5-diphosphapentacyclo[18.3.1.12,5.113,16.017,21]hexacosa-18,20,22-trien-24-one	IC50	276000.0 [1]
	4-(3-Chloro-4-fluoroanilino)-6-(1,3-thiazol-5-yl)quinoline-3-carboxamide	IC50	1210.0 [1]
	(2R,3R,4S,5R)-17-Bromo-3,4,8,10-tetrahydroxy-8,10-dioxo-7,9,11,24-tetraoxa-1,16,18,21-tetraza-8lambda5,10lambda5-diphosphatetracyclo[17.3.1.12,5.016,20]tetracosa-17,19,21-trien-23-one	IC50	27000.0 [1]
	(2R,3R,4S,5R)-17-Azido-3,4,8,10-tetrahydroxy-8,10-dioxo-7,9,11,24-tetraoxa-1,16,18,21-tetraza-8lambda5,10lambda5-diphosphatetracyclo[17.3.1.12,5.016,20]tetracosa-17,19,21-trien-23-one	IC50	6400.0 [1]
	(2R,3R,4S,5R)-3,4,8,10-Tetrahydroxy-8,10-dioxo-7,9,11,24-tetraoxa-1,16,18,21-tetraza-8lambda5,10lambda5-diphosphatetracyclo[17.3.1.12,5.016,20]tetracosa-17,19,21-trien-23-one	IC50	33000.0 [1]
	(2R,3R,4S,5R)-17-Amino-3,4,8,10-tetrahydroxy-8,10-dioxo-7,9,11,24-tetraoxa-1,16,18,21-tetraza-8lambda5,10lambda5-diphosphatetracyclo[17.3.1.12,5.016,20]tetracosa-17,19,21-trien-23-one	IC50	3300.0 [1]
	(2R,3R,4S,5R,13R,14S,15R,16R)-18-Bromo-3,4,8,10,14,15-hexahydroxy-8,10-dioxo-7,9,11,25,26-pentaoxa-1,17,19,22-tetraza-8lambda5,10lambda5-diphosphapentacyclo[18.3.1.12,5.113,16.017,21]hexacosa-18,20,22-trien-24-one	IC50	158000.0 [1]
	4-[[1-Ethyl-2-oxo-6-(1,3-thiazol-5-yl)quinolin-4-yl]amino]-N-methylcyclohexane-1-carboxamide	IC50	58.0 [1]
	4-(Oxan-4-ylamino)-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one	IC50	61.0 [1]
	8-Methyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one	IC50	55.0 [1]
	1,8-Dimethyl-4-(oxan-4-ylamino)-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	52.0 [1]
	4-[[4-(2-Methoxyethoxy)cyclohexyl]amino]-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one	IC50	6.0 [1]
	4-[[4-(2-Methoxyethoxy)cyclohexyl]amino]-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one	IC50	3.9 [1]
	1-Ethyl-4-[[4-(2-methoxyethoxy)cyclohexyl]amino]-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	54.0 [1]
	4-[(4-Methoxycyclohexyl)amino]-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinolin-2-one	IC50	3.8 [1]
	4-[(4-Methoxycyclohexyl)amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	13.0 [1]
	4-[(4-Hydroxycyclohexyl)amino]-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	14.0 [1]
	4-Amino-1-methyl-6-(1,3-thiazol-5-yl)quinolin-2-one	IC50	10773.0 [1]
	N-(4-Methylsulfonylcyclohexyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	959.0 [1]
	N-Ethyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	11400.0 [1]
	N-Propan-2-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	3350.0 [1]
	N-Tert-butyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	2300.0 [1]
	2-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]ethanol	IC50	23400.0 [1]
	N-(2-Methoxyethyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	30200.0 [1]
	N-(3-Chloro-4-fluorophenyl)-8-methoxy-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	4710.0 [1]
	4-[[8-Methoxy-6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]benzamide	IC50	1160.0 [1]
	N-(3-Chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)-8-(trifluoromethyl)quinazolin-4-amine	IC50	1590.0 [1]
	4-[[6-(1,3-Thiazol-5-yl)-8-(trifluoromethyl)quinazolin-4-yl]amino]benzamide	IC50	263.0 [1]
	N-(3-Chloro-4-fluorophenyl)-8-methyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	206.0 [1]
	4-(3-Chloro-4-fluoroanilino)-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinazolin-2-one	IC50	28.0 [1]
	4-[(4-Methoxycyclohexyl)amino]-8-methyl-6-(1,3-thiazol-5-yl)-1H-quinazolin-2-one	IC50	26.0 [1]
	4-[[4-(2-Methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(1,3-thiazol-5-yl)quinazolin-2-one	IC50	64.0 [1]
	4-[(4-Methoxycyclohexyl)amino]-1-methyl-6-(1,3-thiazol-5-yl)quinazolin-2-one	IC50	53.0 [1]
	N-Methyl-4-[[2-methyl-6-(1,3-thiazol-5-yl)-8-(trifluoromethyl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide	IC50	42.0 [1]
	N-Methyl-4-[[8-methyl-6-(1,3-thiazol-5-yl)-2-(trifluoromethyl)quinazolin-4-yl]amino]cyclohexane-1-carboxamide	IC50	245.0 [1]
	4-[[2,8-Dimethyl-6-(1,3-thiazol-5-yl)quinazolin-4-yl]amino]-N-methylcyclohexane-1-carboxamide	IC50	50.0 [1]
	N-Methyl-4-[[2-oxo-6-(1,3-thiazol-5-yl)-1H-quinolin-4-yl]amino]cyclohexane-1-carboxamide	IC50	3.4 [1]
	N-Methyl-4-[[8-methyl-2-oxo-6-(1,3-thiazol-5-yl)-1H-quinolin-4-yl]amino]cyclohexane-1-carboxamide	IC50	1.4 [1]
	N-Methyl-4-[[1-methyl-2-oxo-6-(1,3-thiazol-5-yl)quinolin-4-yl]amino]cyclohexane-1-carboxamide	IC50	4.8 [1]
	4-[[1,8-Dimethyl-2-oxo-6-(1,3-thiazol-5-yl)quinolin-4-yl]amino]-N-methylcyclohexane-1-carboxamide	IC50	5.3 [1]
	N-(3-Chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)quinolin-4-amine	IC50	298.0 [1]
	N-Phenyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	840.0 [1]
	N-(3-Chloro-4-fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	1200.0 [1]
	N-(4-Chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	1320.0 [1]
	N-(3-Chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	700.0 [1]
	N-(2-Chlorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	3610.0 [1]
	N-(4-Fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	2330.0 [1]
	N-(3-Fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	970.0 [1]
	N-(2-Fluorophenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	4680.0 [1]
	N-(4-Methylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	1230.0 [1]
	N-(3-Methylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	1160.0 [1]
	N-(2-Methylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	12800.0 [1]
	6-(1,3-Thiazol-5-yl)-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine	IC50	2150.0 [1]
	4-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]benzenesulfonamide	IC50	700.0 [1]
	N-[4-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]phenyl]methanesulfonamide	IC50	970.0 [1]
	N-(3-Methylsulfonylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	2690.0 [1]
	4-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]benzamide	IC50	560.0 [1]
	N-[4-(1,3-Oxazol-5-yl)phenyl]-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	840.0 [1]
	N-(4-Imidazol-1-ylphenyl)-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	460.0 [1]
	1-[4-[[6-(1,3-Thiazol-5-yl)quinazolin-4-yl]amino]phenyl]pyrrolidin-2-one	IC50	1460.0 [1]
	N-Pyridin-2-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	12300.0 [1]
	N-Pyridin-3-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	3940.0 [1]
	N-Pyridin-4-yl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	950.0 [1]
	N-Cyclopropyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	7830.0 [1]
	N-Cyclobutyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	1930.0 [1]
	N-Cyclopentyl-6-(1,3-thiazol-5-yl)quinazolin-4-amine	IC50	281.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Lymphocyte differentiation antigen CD38 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 5 May. 2024, https://www.aatbio.com/data-sets/lymphocyte-differentiation-antigen-cd38-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 5). Quest Database™ Lymphocyte differentiation antigen CD38 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lymphocyte-differentiation-antigen-cd38-inhibitors-ic50-ki.
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