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Lysine-specific demethylase 4B Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1,5-Bis[(E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzeneIC509300.0 [1]
1,5-Bis[(E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzeneKi3000.0 [1]
N-(4-Pyridin-2-yl-thiazol-2-yl)-benzamideIC5012100.0 [1]
2-{5-[(4-Chloro-2-Methylphenyl)methoxy]-1h-Pyrazol-1-Yl}pyridine-4-Carboxylic AcidIC50170.0 [1]
CID 127030711IC5010.0 [1]
8-Hydroxy-3-[4-(2-naphthalen-1-ylethyl)-1,4-diazepan-1-yl]quinoline-5-carboxylic acidIC501000.0 [1]
N-[6-(Dimethylamino)hexyl]-3-(8-hydroxyquinolin-6-yl)benzamideIC501000.0 [1]
3-[[(1R)-6-(N-Methylanilino)-1,2,3,4-tetrahydronaphthalen-1-yl]methylamino]pyridine-4-carboxylic acidIC5056.0 [1]
Pyrido[3,4-d]pyrimidin-4(3H)-oneIC501000.0 [1]
3-Ethylsulfonyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzamideIC5010900.0 [1]
2-(((2-((2-(Dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acidIC50100.0 [1]
2-(2-Azanyl-1,3-Thiazol-4-Yl)pyridine-4-CarboxamideIC5032700.0 [1]
2-(2-Benzamido-1,3-thiazol-4-yl)pyridine-4-carboxylic acidIC5017000.0 [1]
Lithium;2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylateIC50170.0 [1]
Lithium;2-[(benzylamino)methyl]pyridine-4-carboxylateIC501200.0 [1]
8-(2-Azanyl-1,3-Thiazol-4-Yl)-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC505000.0 [1]
8-(1,3-Thiazol-4-Yl)-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC503100.0 [1]
8-[4-[2-[(4-Fluorophenyl)methyl-Methyl-Amino]ethyl]pyrazol-1-Yl]-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC50390.0 [1]
8-[4-[2-(Dimethylamino)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC502300.0 [1]
8-[4-[2-[4-(4-Chlorophenyl)piperidin-1-Yl]ethyl]pyrazol-1-Yl]-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC5086.0 [1]
8-[4-[2-[4-[(4-Chlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5050.0 [1]
8-Pyrazol-1-yl-3H-pyrido[3,4-d]pyrimidin-4-oneIC504600.0 [1]
8-[4-[2-[4-(3,5-Dichlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5017.0 [1]
8-[[(Phenylmethyl)amino]methyl]-1~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC506500.0 [1]
8-[4-(2-Hydroxyethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC508800.0 [1]
8-(1H-Pyrazol-5-yl)-3H-pyrido[3,4-d]pyrimidin-4-oneIC502800.0 [1]
8-[4-(2-Pyrrolidin-1-ylethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50750.0 [1]
8-[4-(2-Piperidin-1-ylethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50650.0 [1]
8-[4-[2-[(3,4-Dichlorophenyl)methyl-methylamino]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50165.0 [1]
8-[4-[2-[Methyl-[(4-methylsulfonylphenyl)methyl]amino]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50400.0 [1]
4-[[Methyl-[2-[1-(4-oxo-3H-pyrido[3,4-d]pyrimidin-8-yl)pyrazol-4-yl]ethyl]amino]methyl]benzonitrileIC50340.0 [1]
4-[[Methyl-[3-[1-(4-oxo-3H-pyrido[3,4-d]pyrimidin-8-yl)pyrazol-4-yl]propyl]amino]methyl]benzonitrileIC50260.0 [1]
8-(1-Methylpyrazol-3-yl)-3H-pyrido[3,4-d]pyrimidin-4-oneIC509200.0 [1]
8-[(Furan-2-ylmethylamino)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC503100.0 [1]
8-[(4-Methylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC508500.0 [1]
8-[(4-Phenylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5081500.0 [1]
8-[(4-Pyridin-2-ylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5024600.0 [1]
8-[4-[2-[4-(3-Chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-oneIC5031.0 [1]
8-[4-[2-[4-(3,5-Difluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5041.0 [1]
8-[4-[2-[4-(2,4-Difluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5036.0 [1]
8-[4-[2-[4-[3-(Trifluoromethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5039.0 [1]
8-[4-[2-[4-(1,3-Benzodioxol-5-ylmethyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5072.0 [1]
8-[4-[2-[4-(Pyridin-3-ylmethyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50207.0 [1]
8-[4-[2-[4-[(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50247.0 [1]
8-[4-[2-[4-(4-Fluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5061.0 [1]
8-[4-[2-[4-(4-Methoxyphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5039.0 [1]
8-[4-[2-[4-(2-Chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50179.0 [1]
8-[4-[2-(4-Phenylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50274.0 [1]
8-[4-[2-(4-Pyridin-4-ylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5055.0 [1]
8-[4-[2-(4-Thiophen-2-ylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5029.0 [1]
8-(Piperidin-1-ylmethyl)-3H-pyrido[3,4-d]pyrimidin-4-oneIC50100000.0 [1]
8-[(Dimethylamino)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC507800.0 [1]
8-[4-[2-(4-Benzylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50118.0 [1]
8-[4-[2-[4-[(4-Fluorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5079.0 [1]
8-[4-[2-[4-[[4-(Trifluoromethyl)phenyl]methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5062.0 [1]
8-[4-[2-[4-[(3,4-Dichlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5068.0 [1]
8-[4-[2-[4-[(3-Methoxyphenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50149.0 [1]
8-[4-[2-[4-(4-Methylsulfonylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5069.0 [1]
4-[1-[2-[1-(4-Oxo-3H-pyrido[3,4-d]pyrimidin-8-yl)pyrazol-4-yl]ethyl]piperidin-4-yl]benzonitrileIC5069.0 [1]
3-Methylsulfonyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzamideIC5011300.0 [1]
Tcmdc-142577IC506400.0 [1]
N-[[2-[[[2-[2-(Dimethylamino)ethyl-ethylamino]-2-oxoethyl]amino]methyl]pyridin-4-yl]methyl]-2,2,2-trifluoroacetamideIC502500.0 [1]
2-[[4-(Diethylamino)butylamino]methyl]pyridine-4-carbaldehydeIC50250.0 [1]
2-(2-Azanyl-1,3-Thiazol-4-Yl)pyridine-4-Carboxylic AcidIC5083.0 [1]
2-(2-Methyl-1,3-thiazol-4-yl)pyridine-4-carboxylic acidIC502300.0 [1]
2-(1,3-Thiazol-4-yl)pyridine-4-carboxylic acidIC50350.0 [1]
Items per page: 1 - 10 of 66
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysine-specific demethylase 4B Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/lysine-specific-demethylase-4b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Lysine-specific demethylase 4B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysine-specific-demethylase-4b-inhibitors-ic50-ki.
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