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Lysine-specific demethylase 5C Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
▲
▼
8-Hydroxy-5-quinolinecarboxylic acidIC5025000.0 [1], 25118.86 [2]
2-[(1-Benzyl-1h-Pyrazol-4-Yl)oxy]pyrido[3,4-D]pyrimidin-4(3h)-OneIC5063.1 [1], 2500.0 [2]
2-(((2-((2-(Dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acidIC50100.0 [1], 1000.0 [2]
2-[(3-Methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acidIC50100000.0 [1]
2-[1-(Cyclohexylmethyl)pyrazol-4-yl]oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC5079.43 [1], 2500.0 [2]
2-(1-Cyclopentylpyrazol-4-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50125.89 [1], 2500.0 [2]
2-(6-Propan-2-ylpyridin-3-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-oneIC50125.89 [1], 50118.72 [2]
2-(4-Chloro-3-hydroxyphenoxy)-3H-pyrido[3,4-d]pyrimidin-4-oneIC50199.53 [1], 31622.78 [2]
2-(1-Benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-oneIC5031622.78 [1], 100000.0 [2]
2-[(2-Furylmethyl)amino]nicotinic acidIC50100000.0 [1]
3-{[(Furan-2-yl)methyl]amino}pyridine-4-carboxylic acidIC50100.0 [1], 63095.73 [2]
3-[(3-Methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acidIC50125.89 [1], 25118.86 [2]
N-OxalylglycineIC507943.28 [1]
4,6-Dioxoheptanoic acidIC504500.0 [1]
Pyridine-2,4-dicarboxylic acidIC50501.19 [1]
DaminozideIC50100000.0 [1]
Tranylcypromine hydrochlorideIC50100000.0 [1]
Ethyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinateIC501000.0 [1]
4-(Hydroxyamino)-4-oxobutanoic acidIC501900.0 [1]
Kdm5A-IN-1IC5055.0 [1]
Pyrido[3,4-d]pyrimidin-4(3H)-oneIC502000.0 [1]
2,2'-Bipyridine-4-carboxylic acidIC50630.96 [1]
2-[1-[(3R)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC501995.26 [1]
2-(2-Azanyl-1,3-Thiazol-4-Yl)pyridine-4-CarboxamideIC506800.0 [1]
2-[1-(2-Phenylethyl)triazol-4-yl]pyridine-4-carboxylic acidIC507943.28 [1]
2-[1-(2-Phenoxyethyl)triazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[1-(1-Ethoxycarbonylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC503981.07 [1]
2-[1-(1-Propanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC505011.87 [1]
2-[1-(1-Butanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC506309.57 [1]
2-[1-(1-Benzoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acidIC503981.07 [1]
2-[1-[1-(2-Phenylacetyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acidIC503981.07 [1]
2-[1-[1-(3-Phenylpropanoyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acidIC503162.28 [1]
2-[1-(1-Acetylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC50630.96 [1]
2-[1-(1-Propanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC502511.89 [1]
2-[1-(1-Butanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC506309.57 [1]
2-[1-(1-Benzoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC503981.07 [1]
2-[1-[1-(2-Phenylacetyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC506309.57 [1]
2-[1-[1-(3-Phenylpropanoyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC501258.93 [1]
2-[1-(1-Butanoylpyrrolidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC503162.28 [1]
2-[1-[1-(2-Phenylacetyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC506309.57 [1]
2-[1-[1-(3-Phenylpropanoyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC501995.26 [1]
2-[1-(1-Acetylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC502511.89 [1]
2-[1-(1-Propanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC503981.07 [1]
2-[1-(1-Butanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC505011.87 [1]
2-[1-(1-Benzoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acidIC5010000.0 [1]
2-[1-[1-(2-Phenylacetyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC507943.28 [1]
2-[1-[1-(3-Phenylpropanoyl)piperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acidIC505011.87 [1]
5-Chloro-7-[benzoylamino(3-methyl-2-thienyl)methyl]-8-quinolinolIC50178000.0 [1]
Octyl 8-hydroxyquinoline-5-carboxylateIC50100000.0 [1]
2-(2-Benzamido-1,3-thiazol-4-yl)pyridine-4-carboxylic acidIC502000.0 [1]
Lithium;2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylateIC5030.0 [1]
Lithium;2-[(benzylamino)methyl]pyridine-4-carboxylateIC5060.0 [1]
8-(2-Azanyl-1,3-Thiazol-4-Yl)-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC50331.0 [1]
8-(1,3-Thiazol-4-Yl)-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC50830.0 [1]
8-[4-[2-[(4-Fluorophenyl)methyl-Methyl-Amino]ethyl]pyrazol-1-Yl]-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC5078.0 [1]
8-[4-[2-(Dimethylamino)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50340.0 [1]
8-[4-[2-[4-(4-Chlorophenyl)piperidin-1-Yl]ethyl]pyrazol-1-Yl]-3~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC5067.0 [1]
8-[4-[2-[4-[(4-Chlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5023.0 [1]
8-Pyrazol-1-yl-3H-pyrido[3,4-d]pyrimidin-4-oneIC509400.0 [1]
8-[4-[2-[4-(3,5-Dichlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5051.0 [1]
8-[[(Phenylmethyl)amino]methyl]-1~{h}-Pyrido[3,4-D]pyrimidin-4-OneIC50440.0 [1]
8-[4-(2-Hydroxyethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC508400.0 [1]
8-(1H-Pyrazol-5-yl)-3H-pyrido[3,4-d]pyrimidin-4-oneIC507300.0 [1]
8-[4-(2-Pyrrolidin-1-ylethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50150.0 [1]
8-[4-(2-Piperidin-1-ylethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50342.0 [1]
8-[4-[2-[(3,4-Dichlorophenyl)methyl-methylamino]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5080.0 [1]
8-[4-[2-[Methyl-[(4-methylsulfonylphenyl)methyl]amino]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50136.0 [1]
4-[[Methyl-[2-[1-(4-oxo-3H-pyrido[3,4-d]pyrimidin-8-yl)pyrazol-4-yl]ethyl]amino]methyl]benzonitrileIC5076.0 [1]
4-[[Methyl-[3-[1-(4-oxo-3H-pyrido[3,4-d]pyrimidin-8-yl)pyrazol-4-yl]propyl]amino]methyl]benzonitrileIC5064.0 [1]
8-(1-Methylpyrazol-3-yl)-3H-pyrido[3,4-d]pyrimidin-4-oneIC50103400.0 [1]
8-[(Furan-2-ylmethylamino)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50730.0 [1]
8-[(4-Methylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC501300.0 [1]
8-[(4-Phenylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50100000.0 [1]
8-[(4-Pyridin-2-ylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5088000.0 [1]
8-[4-[2-[4-(3-Chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-oneIC5065.0 [1]
8-[4-[2-[4-(3,5-Difluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50126.0 [1]
8-[4-[2-[4-(2,4-Difluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5054.0 [1]
8-[4-[2-[4-[3-(Trifluoromethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5070.0 [1]
8-[4-[2-[4-(1,3-Benzodioxol-5-ylmethyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5021.0 [1]
8-[4-[2-[4-(Pyridin-3-ylmethyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5050.0 [1]
8-[4-[2-[4-[(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5057.0 [1]
8-[4-[2-[4-(4-Fluorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5052.0 [1]
8-[4-[2-[4-(4-Methoxyphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5034.0 [1]
8-[4-[2-[4-(2-Chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50119.0 [1]
8-[4-[2-(4-Phenylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC50142.0 [1]
8-[4-[2-(4-Pyridin-4-ylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5050.0 [1]
8-[4-[2-(4-Thiophen-2-ylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5046.0 [1]
8-(Piperidin-1-ylmethyl)-3H-pyrido[3,4-d]pyrimidin-4-oneIC50111000.0 [1]
8-[(Dimethylamino)methyl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC508400.0 [1]
8-[4-[2-(4-Benzylpiperidin-1-yl)ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5041.0 [1]
8-[4-[2-[4-[(4-Fluorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5021.0 [1]
8-[4-[2-[4-[[4-(Trifluoromethyl)phenyl]methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5022.0 [1]
8-[4-[2-[4-[(3,4-Dichlorophenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5023.0 [1]
8-[4-[2-[4-[(3-Methoxyphenyl)methyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5041.0 [1]
8-[4-[2-[4-(4-Methylsulfonylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-oneIC5032.0 [1]
4-[1-[2-[1-(4-Oxo-3H-pyrido[3,4-d]pyrimidin-8-yl)pyrazol-4-yl]ethyl]piperidin-4-yl]benzonitrileIC5024.0 [1]
4-Hydrazinyl-4-oxobutanoic acidIC50480.0 [1]
N'1,N'1,N'4,N'4-TetramethylsuccinohydrazideIC50100000.0 [1]
3-Methylsulfonyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzamideIC5071900.0 [1]
Tcmdc-142577IC5052800.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysine-specific demethylase 5C Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/lysine-specific-demethylase-5c-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Lysine-specific demethylase 5C Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysine-specific-demethylase-5c-inhibitors-ic50-ki.
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