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Lysophosphatidic acid receptor Edg-2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
CID 10367662IC5046.0 [1], 160.0 [2], 510.0 [3], 762.0 [4]
CID 10367662Ki425.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateIC50109.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateKi18.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateIC50604.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-2-ylmethoxy)phenyl]propyl] dihydrogen phosphateKi156.0 [1]
Chembl4165205IC500.16 [1], 0.19 [2], 86.0 [3]
1-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC5018.0 [1], 20.0 [2]
2-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]acetic acidIC5048.0 [1], 390.0 [2]
1-[4-[3-Fluoro-4-[1-methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC5018.0 [1], 20.0 [2]
1-[4-[4-[1-Methyl-5-[[(1R)-1-[3-(trifluoromethyl)phenyl]ethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC5017.0 [1], 18.0 [2], 340.0 [3]
2-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]triazol-4-yl]phenyl]cyclohexyl]acetic acidIC5058.0 [1], 220.0 [2]
Dodecyl dihydrogen phosphateIC502800.0 [1]
Dodecyl dihydrogen phosphateKi1354.0 [1]
Dioctanoylglycerol pyrophosphateIC505500.0 [1]
Dioctanoylglycerol pyrophosphateKi4300.0 [1]
AM095 free acidIC5025.0 [1], 150.0 [2]
3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acidIC50220.0 [1]
3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acidKi50.0 [1]
CID 66775043IC50160.0 [1]
2-(1,3-Dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic acidIC50609.0 [1]
2-(1,3-Dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic acidKi311.0 [1]
Tetradecyl dihydrogen phosphateIC502300.0 [1]
Tetradecyl dihydrogen phosphateKi1082.0 [1]
2-[4-[[(3,5-Dimethoxy-4-methylbenzoyl)-[(E)-3-phenylprop-2-enyl]amino]methyl]phenyl]acetic acidIC501000.0 [1]
3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acidIC5027354.0 [1]
3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acidKi13470.0 [1]
2-[4-[[(3,5-Dimethoxybenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acidIC5089.0 [1], 50000.0 [2]
Phosphoric acid mono-((E)-tetradec-9-enyl) esterIC503000.0 [1]
Phosphoric acid mono-((E)-tetradec-9-enyl) esterKi1146.0 [1]
Phosphoric acid mono-((E)-tetradec-11-enyl) esterIC502200.0 [1]
Phosphoric acid mono-((E)-tetradec-11-enyl) esterKi457.0 [1]
(1,1-Difluoro-pentadecyl)-phosphonic acidIC502500.0 [1]
(1,1-Difluoro-pentadecyl)-phosphonic acidKi788.0 [1]
[(2S)-3-[4-[(3-Methoxyphenyl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC505660.0 [1]
[(2S)-3-[4-[(3-Methoxyphenyl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi358.0 [1]
2-(3-(4-Nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acidIC5094.0 [1]
2-(3-(4-Nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acidKi48.0 [1]
[(2R)-3-[4-[(3-Methoxyphenyl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC501070.0 [1]
[(2R)-3-[4-[(3-Methoxyphenyl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi34.0 [1]
[(2R)-3-[4-(2,3-Dihydro-1H-inden-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC502930.0 [1]
[(2R)-3-[4-(2,3-Dihydro-1H-inden-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi134.0 [1]
[(2R)-3-[4-(1H-Indol-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC507000.0 [1]
[(2R)-3-[4-(1H-Indol-2-yloxy)phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi73.0 [1]
[(2R)-3-[4-[(4-Ethoxypyridin-2-yl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC50143.0 [1]
[(2R)-3-[4-[(4-Ethoxypyridin-2-yl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi26.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-[[4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methoxy]phenyl]propyl] dihydrogen phosphateIC5084.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-[[4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methoxy]phenyl]propyl] dihydrogen phosphateKi19.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-[(4-propoxypyridin-2-yl)methoxy]phenyl]propyl] dihydrogen phosphateIC50141.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-[(4-propoxypyridin-2-yl)methoxy]phenyl]propyl] dihydrogen phosphateKi64.0 [1]
[(2R)-3-[4-[[4-(2-Methoxyethoxy)pyridin-2-yl]methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC50114.0 [1]
[(2R)-3-[4-[[4-(2-Methoxyethoxy)pyridin-2-yl]methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi35.0 [1]
[(2R)-3-[4-[(4-Methoxy-3,5-dimethylpyridin-2-yl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateIC5062.0 [1]
[(2R)-3-[4-[(4-Methoxy-3,5-dimethylpyridin-2-yl)methoxy]phenyl]-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphateKi28.0 [1]
[2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC505210.0 [1]
[2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateKi137.0 [1]
1-[4-[4-[1-Methyl-5-[[(1R)-1-phenylethoxy]carbonylamino]pyrazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC5020.0 [1], 21.0 [2]
[(1R)-1-Phenylethyl] N-[3-methyl-5-[4-[4-[1-(methylsulfonylcarbamoyl)cyclopropyl]phenyl]phenyl]triazol-4-yl]carbamateIC5018.8 [1], 19.0 [2]
1-[4-[4-[1-Methyl-5-[[(1S)-1-[3-(trifluoromethyl)phenyl]ethoxy]carbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC502650.0 [1], 2660.0 [2]
1-[4-[4-[1-Methyl-5-[[(2R)-3-methylbutan-2-yl]oxycarbonylamino]triazol-4-yl]phenyl]phenyl]cyclopropane-1-carboxylic acidIC5070.0 [1]
[(1R)-1-[3-(Trifluoromethyl)phenyl]ethyl] N-[3-methyl-5-[4-[4-[1-(methylsulfonylcarbamoyl)cyclopropyl]phenyl]phenyl]triazol-4-yl]carbamateIC5024.0 [1], 24.5 [2]
Tetradecylphosphonic acidIC5010000.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-[4-(pyridin-3-ylmethoxy)phenyl]propyl] dihydrogen phosphateIC50992.0 [1]
[(2R)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] dihydrogen phosphateIC502490.0 [1]
(4'-(4-((R)-1-(2-Chlorophenyl)ethoxycarbonylamino)-3-methylisoxazol-5-yl)biphenyl-4-yl)acetic acidIC5017.0 [1]
LPA2 antagonist 1IC5050000.0 [1]
L-NaspaIC5010000.0 [1]
3-(Cyclopentylamino)-2-(2,4-dimethoxyphenyl)-1H-imidazo[1,2-b]pyrazole-7-carbonitrileIC50800000.0 [1]
[1-Bromo-(3S)-hydrox-4-(palmitoyloxy)butyl]phosphateKi170.0 [1]
N-[3-(4-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
4-(4-(4-((1-(2-Chlorophenyl)ethoxy)carbonyl)isoxazol-3-yl)phenylamino)-4-oxobutanoic acidIC50140.0 [1]
Phosphoric acid mono-((E)-dodec-9-enyl) esterIC5010000.0 [1]
2-(4-(4-((1-(2-Chlorophenyl)ethoxy)carbonyl)isoxazol-3-yl)phenethylthio)acetic acidIC50130.0 [1]
2-[1-[(2S)-2-[(S)-(3,5-Dimethoxy-4-methylphenyl)-hydroxymethyl]-5-thiophen-3-ylpentyl]pyrrol-3-yl]acetic acidIC5023.0 [1]
Phosphoric acid mono-((E)-dec-4-enyl) esterIC5010000.0 [1]
3-(4-(4-((1-(2-Chlorocyclohex-1-enyl)ethoxy)carbonyl)isoxazol-3-yl)benzylthio)propanoic acidIC50170.0 [1]
3-(4-(4-((1-(2-Chlorocyclopent-1-enyl)ethoxy)carbonyl)isoxazol-3-yl)benzylthio)propanoic acidIC50130.0 [1]
2-(4-(4-((1-(2-Chlorophenyl)ethoxy)carbonyl)isoxazol-3-yl)benzylthio)ethanesulfonic acidIC50430.0 [1]
2-[1-[(2S,3S)-2-(2,3-Dihydro-1H-inden-2-ylmethyl)-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]pyrrol-3-yl]acetic acidIC5061.0 [1]
3-(4-(4-((1-(2-Chlorophenyl)ethoxy)carbonyl)isoxazol-3-yl)benzylthio)propanoic acidIC50220.0 [1]
3-(4-(4-((1-(2-Chlorophenyl)ethoxy)carbonyl)isoxazol-3-yl)benzylsulfonyl)propanoic acidIC50280.0 [1]
Phosphoric acid monodec-9-enyl esterIC5010000.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-prop-2-ynoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
[(2S)-2-[[(Z)-Octadec-9-enoyl]amino]-3-(4-prop-2-enoxyphenyl)propyl] dihydrogen phosphateIC5010000.0 [1]
(2-Hydroxy-2-sulfanylidene-1,2lambda5-oxaphospholan-5-yl)methyl hexadecanoateKi314.0 [1]
N-[3,5-Bis(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
N-[3-(4-Cyanophenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
N-[3-(3-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
N-[3-[4-(Dimethylcarbamoyl)phenoxy]-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamideIC50800.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-4-yloxyphenyl]-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-3-yloxyphenyl]-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-2-yloxyphenyl]-4-hydroxypiperidine-1-carboxamideIC5025000.0 [1]
2,4-Dichloro-N-(4-chloro-3,5-difluorophenyl)-5-morpholin-4-ylsulfonylbenzamideIC506000.0 [1]
2,4-Dichloro-N-(3,5-dichloro-4-fluorophenyl)-5-morpholin-4-ylsulfonylbenzamideIC5018000.0 [1]
2,4-Dichloro-5-morpholin-4-ylsulfonyl-N-(3,4,5-trifluorophenyl)benzamideIC5014000.0 [1]
3-[4-[[(3,5-Dimethoxybenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acidIC50140.0 [1]
2-[4-[[(3,5-Dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]-5-methylbenzoic acidIC5042.0 [1]
2-[4-[[(3,5-Dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]-6-methylbenzoic acidIC50100.0 [1]
2-[4-[[(3,5-Dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]-3-methylbenzoic acidIC50140.0 [1]
1-[(2S)-2-[(S)-(3,5-Dimethoxy-4-methylphenyl)-hydroxymethyl]-5-phenylpentyl]pyrrole-3-carboxylic acidIC50120.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Lysophosphatidic acid receptor Edg-2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Lysophosphatidic acid receptor Edg-2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-2-inhibitors-ic50-ki.
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