Lysophosphatidic acid receptor Edg-4 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Tetradecylphosphonic acid	IC50	5500.0 [1]
	Tetradecylphosphonic acid	Ki	3550.0 [1]
	3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acid	IC50	22.0 [1]
	3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acid	Ki	20.8 [1]
	3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acid	IC50	9.0 [1]
	3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acid	Ki	7.2 [1]
	(4'-(4-((R)-1-(2-Chlorophenyl)ethoxycarbonylamino)-3-methylisoxazol-5-yl)biphenyl-4-yl)acetic acid	IC50	1700.0 [1]
	LPA2 antagonist 1	IC50	17.0 [1]
	AM095 free acid	IC50	8000.0 [1]
	TC Lpa5 4	IC50	10000.0 [1]
	[3-(4-Nonyl-benzylamino)-propyl]-phosphonic acid	IC50	40.0 [1]
	CID 66775043	IC50	8600.0 [1]
	3-(3-Bromo-5-methoxy-4-(octyloxy)benzylamino)propylphosphonic acid	IC50	80.0 [1]
	[3-(4-Octyl-benzylamino)-propyl]-phosphonic acid	IC50	26.0 [1]
	[1-Bromo-(3S)-hydrox-4-(palmitoyloxy)butyl]phosphate	Ki	170.0 [1]
	N-[3-(4-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	2-[4-[[(3,5-Dimethoxybenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acid	IC50	50000.0 [1]
	[3-(3-Chloro-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	55.0 [1]
	[3-(3-Ethoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	420.0 [1]
	[3-(3-Methyl-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	32.0 [1]
	[3-(3,5-Dichloro-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	6.6 [1]
	[3-(4-Octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	530.0 [1]
	[3-(4-Nonanoyl-benzylamino)-propyl]-phosphonic acid	IC50	250.0 [1]
	[3-(4-Nonyloxy-benzylamino)-propyl]-phosphonic acid	IC50	74.0 [1]
	[3-(3-Methoxy-5-methyl-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	89.0 [1]
	[3-(3-Chloro-5-methoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	57.0 [1]
	[3-(3-Bromo-5-methoxy-4-undecyloxy-benzylamino)-propyl]-phosphonic acid	IC50	42.0 [1]
	[3-(3-Fluoro-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	59.0 [1]
	4-[(3-Phosphono-propylamino)-methyl]-benzoic acid heptyl ester	IC50	700.0 [1]
	{3-[4-(1-Hydroxy-nonyl)-benzylamino]-propyl}-phosphonic acid	IC50	2100.0 [1]
	[3-(3-Methoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	450.0 [1]
	3-[[4-(4-Hexylphenyl)phenyl]methylamino]propylphosphonic acid	IC50	120.0 [1]
	[3-(3-Bromo-4-heptyloxy-5-methoxy-benzylamino)-propyl]-phosphonic acid	IC50	33.0 [1]
	[3-(3,5-Dibromo-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	23.0 [1]
	[3-(3-Hydroxy-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	1200.0 [1]
	[3-(3,5-Dimethyl-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	15.0 [1]
	[3-(3-Bromo-4-octyloxy-benzylamino)-propyl]-phosphonic acid	IC50	36.0 [1]
	[3-(3-Bromo-4-decyloxy-5-methoxy-benzylamino)-propyl]-phosphonic acid	IC50	18.0 [1]
	E,E-3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acid	Ki	21.1 [1]
	N-[3,5-Bis(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide	IC50	25000.0 [1]
	N-[3-(4-Cyanophenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide	IC50	26000.0 [1]
	N-[3-(3-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	N-[3-[4-(Dimethylcarbamoyl)phenoxy]-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-4-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide	IC50	25000.0 [1]
	4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-3-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide	IC50	25000.0 [1]
	4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-2-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide	IC50	25000.0 [1]
	3-[[4-(5-Heptyl-1,2,4-oxadiazol-3-yl)phenyl]methylamino]propylphosphonic acid	IC50	120.0 [1]
	{3-[4-(2-Heptyl-2H-tetrazol-5-yl)-benzylamino]-propyl}-phosphonic acid	IC50	270.0 [1]
	7-Methyl-N-[(2S)-1-[4-(2-methylphenyl)piperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amine	IC50	260.0 [1]
	N-[(2S)-1-[4-(3-Chlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine	IC50	35.0 [1]
	7-Methyl-N-[(2S)-1-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amine	IC50	170.0 [1]
	7-Methyl-N-[(2S)-1-[4-(3-methylphenyl)sulfonylpiperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amine	IC50	310.0 [1]
	N-[(2S)-1-(4-Benzylsulfonylpiperazin-1-yl)propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine	IC50	1860.0 [1]
	7-Methyl-N-[(2S)-1-[4-(2-methylphenyl)sulfonylpiperazin-1-yl]propan-2-yl]thieno[3,2-d]pyrimidin-4-amine	IC50	730.0 [1]
	N-[(2S)-1-(4-Butylsulfonylpiperazin-1-yl)propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine	IC50	6610.0 [1]
	N-[(2S)-1-[4-(2-Methylphenyl)piperazin-1-yl]propan-2-yl]-2-(trifluoromethyl)quinazolin-4-amine	IC50	730.0 [1]
	N-[1-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-methylpropan-2-yl]-2-(trifluoromethyl)quinazolin-4-amine	IC50	30000.0 [1]
	N-[(2S)-1-[4-(2-Methoxyphenyl)piperazin-1-yl]butan-2-yl]-2-(trifluoromethyl)quinazolin-4-amine	IC50	30000.0 [1]
	N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-2-(trifluoromethyl)quinazolin-4-amine	IC50	30000.0 [1]
	N-[(2R)-1-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-2-yl]-2-(trifluoromethyl)quinazolin-4-amine	IC50	30000.0 [1]
	N-[(2S)-1-[4-(2-Methoxyphenyl)piperazin-1-yl]propan-2-yl]-2-(trifluoromethyl)quinazolin-4-amine	IC50	1300.0 [1]
	2-Cyclopropyl-N-[(2S)-1-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-yl]quinazolin-4-amine	IC50	3200.0 [1]
	1-Phenylethyl N-(3-methyl-5-phenyl-1,2-oxazol-4-yl)carbamate	IC50	50000.0 [1]
	2-Cyclopropyl-N-[1-[4-(4-fluorophenyl)piperazin-1-yl]propan-2-yl]quinazolin-4-amine	IC50	1700.0 [1]
	2-[4-[[(3,5-Dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]acetic acid	IC50	23000.0 [1]
	5-Chloro-2-[4-[[(3,5-dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]phenoxy]benzoic acid	IC50	790.0 [1]
	4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-(4-sulfamoylphenoxy)phenyl]-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-[4-(methylcarbamoyl)phenoxy]phenyl]-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	N-[3-(2-Carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	4-(2-Ethylbutyl)-N-[3-(4-fluorophenoxy)-5-(4-methylsulfonylphenoxy)phenyl]-4-hydroxypiperidine-1-carboxamide	IC50	800.0 [1]
	[3-(3-Bromo-4-hexyloxy-5-methoxy-benzylamino)-propyl]-phosphonic acid	IC50	260.0 [1]
	Sodium;[(3S)-1-bromo-3-hydroxy-4-[(Z)-octadec-9-enoyl]oxybutyl]-hydroxyphosphinate	Ki	170.0 [1]
	[(3S)-1-Bromo-4-[(Z)-hexadec-9-enoyl]oxy-3-hydroxybutyl]phosphonic acid	IC50	1420.0 [1]
	(2-Dodecyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate	IC50	7430.0 [1]
	2-(4-Butoxyphenyl)sulfanyl-5-[2-(1-hydroxytridec-2-ynyl)phenyl]benzenesulfonic acid	IC50	40000.0 [1]
	2-(4-Butoxyphenyl)sulfanyl-5-[2-[1-hydroxy-4-(7-hydroxyheptoxy)but-2-ynyl]phenyl]benzenesulfonic acid	IC50	6000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 76 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Lysophosphatidic acid receptor Edg-4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-4-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Lysophosphatidic acid receptor Edg-4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/lysophosphatidic-acid-receptor-edg-4-inhibitors-ic50-ki.
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