Malate dehydrogenase, mitochondrial Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 16124726	IC50	6300.0 [1]
	CID 16124726	Ki	1900.0 [1]
	2',6'-Dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one	IC50	10000.0 [1], 100000.0 [2]
	Methyl 3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoate	IC50	1060.0 [1]
	Methyl 3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoate	Ki	950.0 [1]
	Prop-2-ynyl 3-[[2-[4-(1-adamantyl)-2-[3-(trifluoromethyl)diazirin-3-yl]phenoxy]acetyl]amino]-4-hydroxybenzoate	IC50	5500.0 [1]
	Prop-2-ynyl 3-[[2-[4-(1-adamantyl)-2-[3-(trifluoromethyl)diazirin-3-yl]phenoxy]acetyl]amino]-4-hydroxybenzoate	Ki	4300.0 [1]
	Levothyroxine	IC50	43600.0 [1]
	7-Chloro-4-hydroxyquinoline-3-carboxylic acid	IC50	3630780.55 [1]
	4-Oxo-1H-quinoline-3,7-dicarboxylic acid	IC50	1071519.31 [1]
	3-Quinolinecarboxylic acid, 4-hydroxy-7-(methylsulfonyl)-	IC50	660693.45 [1]
	3-Quinolinecarboxylic acid, 7-(dimethylamino)-1,4-dihydro-4-oxo-	IC50	478630.09 [1]
	4-Hydroxy-7-benzyloxyquinoline-3-carboxylic acid	IC50	32359.37 [1]
	7-Fluoro-4-hydroxyquinoline-3-carboxylic acid	IC50	10471285.48 [1]
	4-Oxo-7-sulfo-1H-quinoline-3-carboxylic acid	IC50	2137962.09 [1]
	4-Oxo-7-sulfamoyl-1H-quinoline-3-carboxylic acid	IC50	954992.59 [1]
	7-Acetyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid	IC50	912010.84 [1]
	4-Hydroxy-7-nitroquinoline-3-carboxylic acid	IC50	1905460.72 [1]
	Paullone Analog 46	IC50	2400.0 [1]
	4,7-Dihydroxy-3-quinolinecarboxylic acid	IC50	489778.82 [1]
	2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-(4-sulfamoylphenyl)acetamide	IC50	10000.0 [1]
	2-[4-[2-[5-Hydroxy-2-[(4-methoxyphenyl)methylcarbamoyl]-4-oxochromen-7-yl]oxyethyl]-2-methoxyanilino]-2-oxoacetic acid	IC50	8480.0 [1]
	7-[(3,4-Dichlorophenyl)methoxy]-4-oxo-1H-quinoline-3-carboxylic acid	IC50	4786.3 [1]
	3-Quinolinecarboxylic acid, 7-(aminocarbonyl)-1,4-dihydro-4-oxo-	IC50	741310.24 [1]
	Methyl 3-[[2-(4-propylphenoxy)acetyl]amino]benzoate	IC50	40000.0 [1]
	Prop-2-ynyl 4-hydroxy-3-[(2-phenoxyacetyl)amino]benzoate	IC50	20000.0 [1]
	2-[4-(1-Adamantyl)phenoxy]-N-[3-(4-prop-2-ynoxybenzoyl)phenyl]acetamide	IC50	20000.0 [1]
	(E)-3-[4-(1-Adamantyl)phenoxy]-N-[3-(4-prop-2-ynoxybenzoyl)phenyl]prop-2-enamide	IC50	20000.0 [1]
	[4-[3-(Trifluoromethyl)diazirin-3-yl]phenyl]methyl 3-[4-[2-(2-hydroxy-5-prop-2-ynoxycarbonylanilino)-2-oxoethoxy]phenyl]adamantane-1-carboxylate	IC50	10200.0 [1]
	[4-[3-(Trifluoromethyl)diazirin-3-yl]phenyl]methyl 3-(4-prop-2-ynoxyphenyl)adamantane-1-carboxylate	IC50	20000.0 [1]
	Prop-2-ynyl 4-hydroxy-3-[[2-[2-[3-(trifluoromethyl)diazirin-3-yl]phenoxy]acetyl]amino]benzoate	IC50	20000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-morpholin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-4-morpholin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(4-cyclopropylpiperazin-1-yl)phenyl]-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-[4-(oxetan-3-yl)piperazin-1-yl]phenyl]-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	5-[3-(4-Acetylpiperazin-1-yl)-2,6-dichlorophenyl]-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-piperazin-1-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-phenylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-[2,6-dichloro-3-(2-chlorophenyl)phenyl]-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-3-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dichloro-3-pyrimidin-5-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(5-Amino-2-chlorophenyl)sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-[2-Chloro-5-(methylamino)phenyl]sulfanyl-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetic acid	IC50	10000.0 [1]
	2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N-methylacetamide	IC50	10000.0 [1]
	2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N,N-dimethylacetamide	IC50	10000.0 [1]
	2-[4-Chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]-N-(2-hydroxyethyl)acetamide	IC50	10000.0 [1]
	Methyl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetate	IC50	10000.0 [1]
	Ethyl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetate	IC50	10000.0 [1]
	Propan-2-yl 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetate	IC50	10000.0 [1]
	[(1S)-1-Phenylethyl] 2-[4-chloro-3-[4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetate	IC50	10000.0 [1]
	2-(2-Chloro-5-hydroxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-propan-2-yloxyphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-hydroxybenzonitrile	IC50	10000.0 [1]
	2-[4-(2,6-Dichloro-3-propan-2-yloxyphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanyl-4-methoxybenzonitrile	IC50	10000.0 [1]
	2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-(2,6-dichloro-3-pyridin-4-ylphenyl)-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	Ethyl 2-[4-chloro-3-[4-(2,6-dichloro-3-phenylphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylphenyl]acetate	IC50	10000.0 [1]
	2-(2-Chloro-5-methoxyphenyl)sulfanyl-5-[2,6-dichloro-3-(oxan-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-one	IC50	10000.0 [1]
	Methyl 3-[[2-(4-cyclohexylphenoxy)acetyl]amino]benzoate	IC50	40000.0 [1]
	1-[4-[[4-(Trifluoromethyl)phenyl]methyl]piperazin-1-yl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanone	IC50	5400.0 [1]
	Methyl 3-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]butanoylamino]benzoate	IC50	1110.0 [1]
	Methyl 4-hydroxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	1890.0 [1]
	Methyl 3-[[2-[4-(1-adamantyl)phenoxy]-2-methylpropanoyl]amino]benzoate	IC50	1360.0 [1]
	N-[4-(Trifluoromethyl)phenyl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamide	IC50	1530.0 [1]
	Methyl 3-[[2-(4-cyclopentylphenoxy)acetyl]amino]benzoate	IC50	40000.0 [1]
	Methyl 4-(2-morpholin-4-ylethoxy)-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	40000.0 [1]
	N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamide	IC50	2900.0 [1]
	N-(3-Hydroxy-1-adamantyl)-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetamide	IC50	26900.0 [1]
	Methyl 4-prop-2-ynoxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	1690.0 [1]
	Methyl 3-[[2-methyl-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoyl]amino]benzoate	IC50	1320.0 [1]
	Methyl 3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	8920.0 [1]
	Methyl 4-methoxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	27470.0 [1]
	1-(4-Prop-2-ynylpiperazin-1-yl)-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanone	IC50	40000.0 [1]
	Methyl 4-hydroxy-3-[4-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]butanoylamino]benzoate	IC50	1110.0 [1]
	Methyl 3-[[2-(4-pentylphenoxy)acetyl]amino]benzoate	IC50	40000.0 [1]
	Methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-(2-pyrrolidin-1-ylethoxy)benzoate	IC50	40000.0 [1]
	Methyl 4-hydroxy-3-[3-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoylamino]benzoate	IC50	4600.0 [1]
	Methyl 3-[[2-(4-butylphenoxy)acetyl]amino]benzoate	IC50	40000.0 [1]
	Methyl 4-hydroxy-3-[[2-methyl-2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]propanoyl]amino]benzoate	IC50	10980.0 [1]
	Methyl 4-(2-methoxyethoxy)-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	29020.0 [1]
	Prop-2-ynyl 4-hydroxy-3-[[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]acetyl]amino]benzoate	IC50	5880.0 [1]
	Methyl 3-[[2-[4-(1-adamantyl)phenoxy]acetyl]amino]-4-(3-morpholin-4-ylpropoxy)benzoate	IC50	40000.0 [1]
	Methyl 3-[2-(4-methylphenoxy)acetamido]benzoate	IC50	40000.0 [1]
	Methyl 3-[[2-(4-ethylphenoxy)acetyl]amino]benzoate	IC50	40000.0 [1]
	Methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate	IC50	13500.0 [1]
	5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	2700.0 [1]
	5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	1600.0 [1]
	5-Benzyl-9-(trifluoromethyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	4200.0 [1]
	5-Benzyl-9-methyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	6200.0 [1]
	9-Bromo-5-[(4-methylphenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	1600.0 [1]
	9-Bromo-5-[(4-methoxyphenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	1800.0 [1]
	9-Bromo-5-[(3,4-dichlorophenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	1100.0 [1]
	5-[(4-Methylphenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	10500.0 [1]
	5-[(3,4-Dichlorophenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	7900.0 [1]
	9-Tert-butyl-5-[(3,4-dichlorophenyl)methyl]-7,12-dihydroindolo[3,2-d][1]benzazepin-6-one	IC50	770.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Malate dehydrogenase, mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/malate-dehydrogenase-mitochondrial-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Malate dehydrogenase, mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/malate-dehydrogenase-mitochondrial-inhibitors-ic50-ki.
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