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Maltase-glucoamylase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
GenisteinIC502610.0 [1], 10400.0 [2]
GenisteinKi10400.0 [1]
1-DeoxynojirimycinIC5040.0 [1], 360.0 [2], 2000.0 [3]
MiglitolIC503700.0 [1], 6000.0 [2]
MiglitolKi1000.0 [1]
(2S,3R,4S,5S)-6-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-4-methoxyhexane-1,2,3,5-tetrolKi500.0 [1]
MiglustatIC502100.0 [1], 9000.0 [2]
ValienamineIC50100000.0 [1], 340000.0 [2]
AMP-DeoxynojirimycinIC503000.0 [1], 4000.0 [2]
(2S,3R,4R,5S)-1-[5-(1-Adamantylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50500000.0 [1], 1000000.0 [2]
(5Z)-3-[(E)-2-[(1R,4As,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethenyl]-5-[(4-methoxyphenyl)methylidene]furan-2-oneIC5016000.0 [1]
(2R,3R,5R,6R)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triolIC50110000.0 [1]
(2R,3R,5R,6R)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triolKi6200.0 [1]
(2S,3R,4S,5S)-6-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]hexane-1,2,3,4,5-pentolKi43.0 [1]
(2R,3R,5R,6S)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triolIC503200.0 [1]
(2R,3R,5R,6S)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triolKi450.0 [1]
(R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triolIC50700.0 [1]
(R)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triolKi6900.0 [1]
[(2S,3S,4R,5R,6S)-1-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-2,4,5,6,7-pentahydroxyheptan-3-yl] hydrogen sulfateKi190.0 [1]
[(2S,3S)-4-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-1,3-dihydroxybutan-2-yl] hydrogen sulfateIC504900.0 [1]
[(2S,3S)-4-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-1,3-dihydroxybutan-2-yl] hydrogen sulfateKi1000.0 [1]
PrecoseIC50906000.0 [1]
3,4-Pyrrolidinediol, 2-(hydroxymethyl)-1-methyl-, (2R,3R,4R)-IC50500000.0 [1]
VogliboseIC501300.0 [1]
1,4-Dideoxy-1,4-imino-d-arabinitolIC5055000.0 [1]
MigalastatIC501500.0 [1]
LucerastatIC5010000.0 [1]
Conduritol epoxideIC50100000.0 [1]
N-MethyldeoxynojirimycinIC50120.0 [1]
2,5-Dideoxy-2,5-imino-D-mannitolIC5050000.0 [1]
(2r,3r,5s,6r)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triolIC5040.0 [1]
ValiolamineIC502200.0 [1]
ValidamineIC50110000.0 [1]
(3R,4R,5S,6R)-5-[(2S,3S,4S,5R,6S)-5-[(2S,3S,4R,5R,6S)-3,4-Dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triolIC5015200.0 [1]
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3R,4R,5S)-IC501000000.0 [1]
(2S,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triolIC501000000.0 [1]
N-Methyl-2,5-dideoxy-2,5-imino-D-mannitolIC5050000.0 [1]
(2R,3R,5S,6S)-2,6-Bis(hydroxymethyl)piperidine-3,4,5-triolIC508400.0 [1]
2,6-Bis-hydroxymethyl-1-methyl-piperidine-3,4,5-triolIC5060.0 [1]
3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3S,4R,5S)-IC501000000.0 [1]
(5Z)-3-[(E)-2-[(1R,4As,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethenyl]-5-benzylidenefuran-2-oneIC5058000.0 [1]
(2R,3S,4R,5S)-1-[5-(1-Adamantylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC5015000.0 [1]
(2R,3R,4R)-1-Butyl-2-(hydroxymethyl)pyrrolidine-3,4-diolIC5050000.0 [1]
(2R,3R,4R,5R)-1-Butyl-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diolIC5050000.0 [1]
De-O-Sulfonated KotalanolKi30.0 [1]
(2R,3R,5S,6R)-1-Butyl-2,6-bis(hydroxymethyl)piperidine-3,4,5-triolIC504200.0 [1]
5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC506.1 [1]
(2R,3R,4R,5S)-1-[4,4-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC509000.0 [1]
(2S,3R,4R,5S)-1-[5-[(3-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
5-(2-Hydroxy-1-hydroxymethyl-ethylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC50550.0 [1]
(2S,3S)-4-[(2R,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]butane-1,2,3-triolIC509000.0 [1]
(2S,3S,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triolIC501000000.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC507000.0 [1]
(2S,3R,4R,5S)-1-[5-[(2-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(4-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC508000.0 [1]
(2R,3R,4R,5S)-1-[5-[(2-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC502500.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(4-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC502000.0 [1]
(2R,3R,4R,5S)-1-[5-[(3-Fluoro-4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC503000.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(2-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC501500.0 [1]
(2R,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(2-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(1S,2S,3R,4S,5S)-5-[Bis(hydroxymethyl)amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC5015.0 [1]
5-(Cyclohexylmethyl-amino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC50240.0 [1]
5-Cyclohexylamino-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC50410.0 [1]
5-(4-Bromo-benzylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC50230.0 [1]
6-(2-Hydroxy-1-hydroxymethyl-ethylamino)-4-hydroxymethyl-cyclohex-4-ene-1,2,3-triolIC505900.0 [1]
1-Hydroxymethyl-5-phenethylamino-cyclohexane-1,2,3,4-tetraolIC50100.0 [1]
5-(3,7-Dimethyl-octa-2,6-dienylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC50520.0 [1]
(1S,2S,3R,4S,5S)-5-[[(1S,2S)-2-Hydroxycyclohexyl]amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrolIC501600.0 [1]
1-Hydroxymethyl-5-[(thiophen-2-ylmethyl)-amino]-cyclohexane-1,2,3,4-tetraolIC50200.0 [1]
5-(3,5-Di-tert-butyl-4-hydroxy-benzylamino)-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraolIC5043.0 [1]
1-Hydroxymethyl-5-(3-phenyl-allylamino)-cyclohexane-1,2,3,4-tetraolIC50270.0 [1]
1-Hydroxymethyl-5-[(pyridin-3-ylmethyl)-amino]-cyclohexane-1,2,3,4-tetraolIC50330.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(3-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC501500.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC502500.0 [1]
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1R)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC504000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1R)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(3-phenylphenyl)methoxy]pentyl]piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
(2S,3R,4R,5S)-1-[4,4-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triolIC50100000.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(Z)-pyridin-2-ylmethylideneamino]benzamideIC5010230.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-thiophen-2-ylmethylideneamino]benzamideIC508480.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(Z)-furan-2-ylmethylideneamino]benzamideIC5012750.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(4-nitrophenyl)methylideneamino]benzamideIC5026380.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(4-fluorophenyl)methylideneamino]benzamideIC507120.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(3,5-dimethoxyphenyl)methylideneamino]benzamideIC5016170.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-benzylideneamino]benzamideIC508050.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(3-bromo-4-fluorophenyl)methylideneamino]benzamideIC5028020.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(4-methoxyphenyl)methylideneamino]benzamideIC5018330.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(4-chlorophenyl)methylideneamino]benzamideIC505310.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(3-methoxyphenyl)methylideneamino]benzamideIC5011090.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(3-hydroxyphenyl)methylideneamino]benzamideIC509210.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(3-hydroxy-2-iodo-4-methoxyphenyl)methylideneamino]benzamideIC5044800.0 [1]
4-(1,3-Benzothiazol-2-yl)-N-[(E)-(3,5-dihydroxyphenyl)methylideneamino]benzamideIC5011120.0 [1]
(2R,3S,4S)-1-[(2S,3S)-2,4-Dihydroxy-3-pentoxybutyl]-2-(hydroxymethyl)thiolan-1-ium-3,4-diol;chlorideIC501500.0 [1]
(2R,3S,4S)-1-[(2S,3S)-3-Heptoxy-2,4-dihydroxybutyl]-2-(hydroxymethyl)thiolan-1-ium-3,4-diol;chlorideIC50640.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Maltase-glucoamylase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/maltase-glucoamylase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Maltase-glucoamylase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/maltase-glucoamylase-inhibitors-ic50-ki.
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