 | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole | IC50 | 48.0 [1] |
| 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole | Ki | 18.0 [1], 57.0 [2] |
 | Doramapimod | IC50 | 17.0 [1] |
| Doramapimod | Ki | 0.1 [1], 6.4 [2], 22.0 [3], 46.0 [4] |
 | Neflamapimod | IC50 | 51.0 [1] |
 | 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole | IC50 | 28.0 [1] |
 | [5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-YL](3-{[(2R)-2,3-dihydroxypropyl]oxy}phenyl)methanone | IC50 | 400.0 [1] |
 | N~3~-Cyclopropyl-N~4~'-(Cyclopropylmethyl)-6-Methylbiphenyl-3,4'-Dicarboxamide | IC50 | 18.0 [1], 199.53 [2], 1584.89 [3] |
| N~3~-Cyclopropyl-N~4~'-(Cyclopropylmethyl)-6-Methylbiphenyl-3,4'-Dicarboxamide | Ki | 9.0 [1], 10.0 [2], 12.0 [3], 12.59 [4] |
 | Sorafenib | IC50 | 84.2 [1] |
 | 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide | IC50 | 1.05 [1], 5.8 [2], 17.4 [3], 247.0 [4] |
| 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide | Ki | 2.9 [1], 5.8 [2] |
 | Benzamide, 3-((4-(6-methyl-2-pyridinyl)-5-(6-quinoxalinyl)-1H-imidazol-2-yl)methyl)- | IC50 | 480.0 [1] |
 | 4-(2-Cyanophenoxy)-N-(pyridin-4-ylmethyl)benzamide | IC50 | 600.0 [1], 5400.0 [2], 10000.0 [3], 21000.0 [4], 25000.0 [5] |
| 4-(2-Cyanophenoxy)-N-(pyridin-4-ylmethyl)benzamide | Ki | 290.0 [1] |
 | N-[5-(Dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | IC50 | 61.0 [1], 970.0 [2], 1500.0 [3], 9700.0 [4], 10000.0 [5] |
| N-[5-(Dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | Ki | 14.0 [1] |
 | 2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine | IC50 | 590.0 [1], 594.0 [2], 668.0 [3] |
 | Losmapimod | IC50 | 25.12 [1], 100.0 [2] |
| Losmapimod | Ki | 7.94 [1], 63.1 [2] |
 | Talmapimod | IC50 | 9.0 [1], 10.0 [2], 36.0 [3], 96.0 [4] |
 | N-[4-Methyl-3-[[4-(1,3-thiazol-4-ylmethoxy)benzoyl]amino]phenyl]-3-morpholin-4-ylbenzamide | IC50 | 10.0 [1], 15.85 [2], 17.0 [3], 25.12 [4], 1258.93 [5] |
 | 7-(1-Tert-butylpiperidin-4-yl)-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)quinolin-2-one | IC50 | 0.08 [1], 0.14 [2], 1.7 [3], 2.4 [4], 28.0 [5] |
 | N-Cyclopropyl-3-(4'-hydroxy-2-oxospiro[1H-indole-3,1'-cyclohexane]-6-yl)-4-methylbenzamide | IC50 | 1.4 [1], 5.0 [2], 11.0 [3] |
 | CK1 Inhibitor | IC50 | 4154.0 [1], 5800.0 [2], 12000.0 [3] |
 | 4-(4-Fluorophenyl)-1-(4-piperidinyl)-5-(2-amino-4-pyrimidinyl)-imidazole | IC50 | 19.0 [1], 20.0 [2] |
 | Skepinone-L | IC50 | 5.0 [1], 40.0 [2] |
 | 4-(4-(4-Fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)-2-methoxypyrimidine | IC50 | 19.0 [1], 40.0 [2], 130.0 [3] |
| 4-(4-(4-Fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)-2-methoxypyrimidine | Ki | 36.0 [1] |
 | N-[3-[4-(Cyclopropylmethylcarbamoyl)phenyl]-4-methylphenyl]furan-3-carboxamide | IC50 | 16.0 [1] |
| N-[3-[4-(Cyclopropylmethylcarbamoyl)phenyl]-4-methylphenyl]furan-3-carboxamide | Ki | 6.0 [1], 15.0 [2] |
 | 3-(2,4-Difluoroanilino)-6H-benzo[c][1]benzoxepin-11-one | IC50 | 239.0 [1], 240.0 [2], 22000.0 [3] |
 | Methyl 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate | IC50 | 1.0 [1], 2.0 [2] |
 | 1-(2,6-Dichlorophenyl)-5-(2-chlorophenyl)-7-methoxy-3,4-dihydro-2(1H)-quinazolinone | IC50 | 1.0 [1], 6.0 [2] |
 | 1-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-7-(4-piperidinyl)-1,2,3,4-tetrahydroquinazoline-2-one | IC50 | 0.2 [1] |
 | N-Cyclopropyl-4-Methyl-3-(2'-Oxo-1',2'-Dihydrospiro[cyclopentane-1,3'-Indol]-6'-Yl)benzamide | IC50 | 1.3 [1], 18.0 [2] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-N-(oxan-4-yl)pyridin-2-amine | IC50 | 5.0 [1], 180.0 [2] |
 | 13-(2,4-Difluoroanilino)-5-(3-hydroxypropoxy)tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one | IC50 | 8.0 [1], 13.0 [2], 190.0 [3], 191.0 [4] |
 | 13-(2,4-Difluoroanilino)-5-hydroxytricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one | IC50 | 20.0 [1], 49.0 [2], 700.0 [3], 1247.0 [4] |
 | 13-(2,4-Difluoroanilino)-5-[(2S)-2,3-dihydroxypropoxy]tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one | IC50 | 8.0 [1], 17.0 [2], 52.0 [3], 60.0 [4] |
 | 13-(2,4-Difluoroanilino)-5-methoxytricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one | IC50 | 20.0 [1], 44.0 [2], 1200.0 [3], 1647.0 [4] |
 | 13-(2,4-Difluoroanilino)-5-(2-hydroxyethoxy)tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one | IC50 | 10.0 [1], 19.0 [2], 480.0 [3], 583.0 [4] |
 | 2-(4-Fluorophenyl)-N-[4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]pyridin-2-yl]acetamide | IC50 | 9.0 [1], 2980.0 [2] |
 | 13-(3-Benzamido-4-fluoroanilino)-N-(2-morpholin-4-ylethyl)-2-oxotricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene-5-carboxamide | IC50 | 0.2 [1], 31.0 [2], 38.0 [3] |
 | N-Benzyl-4-(2-cyanophenoxy)benzamide | IC50 | 450.0 [1], 1400.0 [2], 10000.0 [3], 100000.0 [4] |
 | 4-(2-Cyanophenoxy)-N-(pyridin-3-ylmethyl)benzamide | IC50 | 560.0 [1], 4700.0 [2], 10000.0 [3], 15000.0 [4] |
 | 4-(2-Cyanophenoxy)-N-(pyrimidin-4-ylmethyl)benzamide | IC50 | 2800.0 [1], 7100.0 [2], 10000.0 [3], 100000.0 [4] |
 | N-(5-Cyano-2-methylphenyl)-1-phenyl-5-propylpyrazole-4-carboxamide | IC50 | 15.0 [1], 210.0 [2], 890.0 [3], 10000.0 [4] |
 | 4-Methyl-3-[(1-phenyl-5-propylpyrazole-4-carbonyl)amino]benzoic acid | IC50 | 86.0 [1], 4200.0 [2], 10000.0 [3], 21000.0 [4] |
 | N-[5-[[14-[(2S)-2,3-Dihydroxypropoxy]-2-oxo-6-tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaenyl]amino]-2-fluorophenyl]benzamide | IC50 | 1.0 [1], 3.0 [2], 280.0 [3] |
 | 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole | IC50 | 110.0 [1], 400.0 [2], 820.0 [3] |
 | 1-(5-Tert-butyl-2-methyl-2H-pyrazol-3-YL)-3-(4-chloro-phenyl)-urea | IC50 | 794.33 [1], 16800.0 [2], 21000.0 [3] |
 | 4-(5-(4-Fluorophenyl)-3-(4-piperidyl)imidazol-4-yl)pyridine | IC50 | 38.0 [1], 60.0 [2] |
| 4-(5-(4-Fluorophenyl)-3-(4-piperidyl)imidazol-4-yl)pyridine | Ki | 60.0 [1] |
 | 2-Amino-Phenylamino-Dibenzosuberone | IC50 | 50.0 [1], 100.0 [2], 104.0 [3] |
 | N-(3-Cyanophenyl)-2'-Methyl-5'-(5-Methyl-1,3,4-Oxadiazol-2-Yl)-4-Biphenylcarboxamide | Ki | 240.0 [1] |
 | N-Cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide | IC50 | 15.85 [1], 17.38 [2], 27.54 [3] |
 | 2-Phenoxy-4-[1-(piperidine-4-yl)-4-(4-fluorophenyl)-5-imidazolyl]pyrimidine | IC50 | 19.0 [1], 19.2 [2], 20.0 [3] |
 | 4-Phenoxy-N-(pyridin-4-ylmethyl)benzamide | IC50 | 2300.0 [1], 4000.0 [2], 10000.0 [3] |
 | 4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide | IC50 | 4700.0 [1], 10000.0 [2], 22000.0 [3] |
 | N-{4'-[(Cyclopropylmethyl)carbamoyl]-6-Methylbiphenyl-3-Yl}-2-Morpholin-4-Ylpyridine-4-Carboxamide | IC50 | 6.0 [1] |
| N-{4'-[(Cyclopropylmethyl)carbamoyl]-6-Methylbiphenyl-3-Yl}-2-Morpholin-4-Ylpyridine-4-Carboxamide | Ki | 4.4 [1], 6.0 [2] |
 | 4-[3-Methyl-2-piperidin-4-yl-5-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-N-[(1S)-1-phenylethyl]pyridin-2-amine | IC50 | 0.1 [1], 2.0 [2], 34.0 [3] |
 | N-[2-Methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide | IC50 | 3.5 [1], 4.0 [2] |
 | 3-(2-Aminoquinazolin-6-Yl)-4-Methyl-N-[3-(Trifluoromethyl)phenyl]benzamide | IC50 | 6.0 [1] |
 | N-(4-(2-(Phenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamide | IC50 | 180.0 [1], 199.53 [2] |
 | N-[4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfinylimidazol-4-yl]pyridin-2-yl]acetamide | IC50 | 500.0 [1], 710.0 [2], 1072.0 [3] |
 | 4-[3-(4-Fluorophenyl)-5-isopropylisoxazol-4-yl]pyridine | IC50 | 450.0 [1] |
 | 4-[5-(4-Fluorophenyl)-3-isopropylisoxazol-4-yl]pyridine | IC50 | 2200.0 [1] |
 | N-(Cyclopropylmethyl)-2'-Methyl-5'-(5-Methyl-1,3,4-Oxadiazol-2-Yl)biphenyl-4-Carboxamide | Ki | 480.0 [1] |
 | 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piperidin-4-ylamino)-3,4-dihydroquinazolin-2(1H)-one | IC50 | 0.5 [1] |
 | 1-Methyl-3-tert-butyl-5-[3-(2,3-dichlorophenyl)ureido]-1H-pyrazole | IC50 | 53.0 [1] |
 | 6-(2,4-Difluoroanilino)tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-one | IC50 | 95.0 [1], 130.0 [2], 1907.0 [3] |
 | 1-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-7-piperazin-1-YL-3,4-dihydroquinazolin-2(1H)-one | IC50 | 2.6 [1] |
 | 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-piperazin-1-yl-3,4-dihydroquinazolin-2-one | IC50 | 1.4 [1] |
 | 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-piperidin-4-yloxy-3,4-dihydroquinazolin-2-one | IC50 | 0.2 [1] |
 | 5-(2-Chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(piperazine-1-carbonyl)-3,4-dihydroquinazolin-2-one | IC50 | 1.1 [1] |
 | 2-(2-Chloro-4-fluorophenyl)sulfanyl-5-(2,6-dichlorophenyl)pyrimido[1,6-b]pyridazin-6-one | IC50 | 36.0 [1], 53.0 [2], 275.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(4-methylphenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 370.0 [1], 870.0 [2], 1400.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(phenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one | IC50 | 250.0 [1], 400.0 [2], 460.0 [3] |
 | 2-(3-Chlorophenyl)sulfanyl-5-(2,6-dichlorophenyl)pyrimido[1,6-b]pyridazin-6-one | IC50 | 280.0 [1], 350.0 [2], 900.0 [3] |
 | 2-(4-Chloro-2-methylphenyl)sulfanyl-5-(2,6-dichlorophenyl)pyrimido[1,6-b]pyridazin-6-one | IC50 | 160.0 [1], 180.0 [2] |
 | 5-(2,6-Dichlorophenyl)-2-(3,4-dichlorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 800.0 [1], 970.0 [2], 1200.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(4-fluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 99.0 [1], 123.0 [2], 293.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(2,4-dimethylphenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 260.0 [1], 320.0 [2], 690.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(2-hydroxyphenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 140.0 [1], 360.0 [2], 490.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(3,4-dimethylphenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 1900.0 [1], 2400.0 [2], 3500.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(3-fluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 440.0 [1], 450.0 [2], 720.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(3-methylphenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 210.0 [1], 280.0 [2], 1400.0 [3] |
 | 5-(2,6-Dichlorophenyl)-2-(2-methylphenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one | IC50 | 200.0 [1], 330.0 [2], 3700.0 [3] |
 | 2-(2-Amino-4-fluorophenyl)sulfanyl-5-(2,6-dichlorophenyl)pyrimido[1,6-b]pyridazin-6-one | IC50 | 220.0 [1], 280.0 [2], 1200.0 [3] |
 | 2-(3-Chloro-4-fluorophenyl)sulfanyl-5-(2,6-dichlorophenyl)pyrimido[1,6-b]pyridazin-6-one | IC50 | 180.0 [1], 480.0 [2], 500.0 [3] |
 | N-[4-Methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]phenyl]-2-morpholin-4-ylpyridine-4-carboxamide | IC50 | 26.3 [1], 123.03 [2], 416.87 [3] |
 | 1-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-7-methoxy-3,4-dihydro-2(1H)-quinazolinone | IC50 | 10.99 [1], 11.0 [2] |
 | 5-(2-Chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-piperidin-4-yl-3,4-dihydroquinazolin-2-one | IC50 | 0.1 [1] |
 | 1-(2,6-Dichlorophenyl)-5-(2-chloro-4-fluorophenyl)-7-methoxy-3,4-dihydro-2(1H)-quinazolinone | IC50 | 3.0 [1] |
 | 1-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-7-(piperidin-4-ylamino)-3,4-dihydroquinazolin-2-one | IC50 | 0.6 [1] |
 | 1-(2,6-Dichlorophenyl)-5-(2-chlorophenyl)-7-(4-piperidinyl)-1,2,3,4-tetrahydroquinazoline-2-one | IC50 | 0.9 [1] |
 | Cyclohexyl-{4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]pyridin-2-yl}amine | IC50 | 20.0 [1], 27.0 [2], 170.0 [3] |
 | 2-(4-Fluorophenyl)-3-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]imidazo[1,2-a]pyrimidin-7-amine | IC50 | 1.0 [1], 6.0 [2], 8.5 [3] |
Calculator
