 | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole | IC50 | 83.0 [1] |
 | 4-[5-(4-Fluorophenyl)-2-(4-methanesulfinyl-benzylsulfanyl)-3H-imidazol-4-yl]pyridine | IC50 | 2780.0 [1] |
 | 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole | IC50 | 400.0 [1], 520.0 [2], 5500.0 [3], 12000.0 [4], 27000.0 [5] |
 | Neflamapimod | IC50 | 0.8 [1], 10.0 [2], 70.0 [3], 150.0 [4], 700.0 [5] |
 | p38 MAP Kinase Inhibitor III | IC50 | 39.0 [1], 160.0 [2], 380.0 [3], 990.0 [4], 2700.0 [5] |
 | 4-(5-(4-Fluorophenyl)-3-(4-piperidyl)imidazol-4-yl)pyridine | IC50 | 50.0 [1], 71.0 [2], 90.0 [3], 125.0 [4], 272.0 [5] |
 | CID 10450926 | IC50 | 75.0 [1], 500.0 [2], 1100.0 [3], 10800.0 [4], 12500.0 [5] |
 | (4-((2-Amino-4-bromophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone | IC50 | 4.0 [1], 5.0 [2], 17.0 [3], 30.0 [4], 74.0 [5] |
 | 2-(Methylthio)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole | IC50 | 44.0 [1], 630.0 [2], 900.0 [3], 1200.0 [4], 4200.0 [5] |
 | 4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanylimidazol-4-yl]-N-(1-phenylethyl)pyridin-2-amine | IC50 | 15.0 [1], 110.0 [2], 220.0 [3], 3000.0 [4], 4100.0 [5] |
 | 4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanylimidazol-4-yl]pyridine | IC50 | 450.0 [1], 1080.0 [2], 2200.0 [3], 5100.0 [4] |
 | 4-(2-Aminophenylamino)-2-chloro-2'-methylbenzophenone | IC50 | 6.0 [1], 12.0 [2], 14.0 [3], 18.0 [4] |
 | N-[4-[5-(4-Fluorophenyl)-2-methylsulfanyl-3-(2,2,6,6-tetramethylpiperidin-4-yl)imidazol-4-yl]pyridin-2-yl]acetamide | IC50 | 340.0 [1], 460.0 [2], 2150.0 [3], 4500.0 [4], 5400.0 [5] |
 | 5-(4-Fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-4-pyridin-4-ylpyrimidine | IC50 | 5600.0 [1], 14100.0 [2], 36000.0 [3], 45500.0 [4], 95500.0 [5] |
 | N-Ethyl-4-[5-(4-fluorophenyl)-2-methylsulfanyl-3-(2,2,6,6-tetramethylpiperidin-4-yl)imidazol-4-yl]pyridin-2-amine | IC50 | 220.0 [1], 620.0 [2], 2700.0 [3], 2900.0 [4], 11000.0 [5] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-3-(2,2,6,6-tetramethylpiperidin-4-yl)imidazol-4-yl]pyridine | IC50 | 850.0 [1], 16000.0 [2], 17000.0 [3], 18500.0 [4], 19100.0 [5] |
 | N-Ethyl-4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanylimidazol-4-yl]pyridin-2-amine | IC50 | 71.0 [1], 600.0 [2], 700.0 [3], 2000.0 [4], 5000.0 [5] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-2-propan-2-yloxypyridine | IC50 | 47.0 [1], 400.0 [2], 560.0 [3], 2200.0 [4], 7200.0 [5] |
 | [2-Chloro-4-(4-fluoro-2-methyl-phenylamino)-phenyl]-o-tolyl-methanone | IC50 | 4.0 [1], 17.0 [2], 35.0 [3], 51.0 [4], 79.0 [5] |
 | 6-(4-Fluorophenyl)-7-[2-[[(2S)-3-hydroxy-3-methylbutan-2-yl]amino]pyrimidin-4-yl]-2,3-dihydro-1H-pyrazolo[1,2-a]pyrazol-5-one | IC50 | 8.0 [1], 22.0 [2], 42.0 [3], 54.0 [4] |
 | 4-[4-(4-Fluorophenyl)-2-[(3-methylsulfinylphenyl)methylsulfanyl]-1H-imidazol-5-yl]pyridine | IC50 | 1000.0 [1], 4100.0 [2], 23500.0 [3], 33500.0 [4] |
 | 4-[4-(4-Fluorophenyl)-2-[(2-methylsulfinylphenyl)methylsulfanyl]-1H-imidazol-5-yl]pyridine | IC50 | 900.0 [1], 4000.0 [2], 15000.0 [3], 47500.0 [4] |
 | 6-(4-Fluorophenyl)-7-[2-[[(1S)-1-phenylethyl]amino]pyrimidin-4-yl]-2,3-dihydro-1H-pyrazolo[1,2-a]pyrazol-5-one | IC50 | 0.4 [1], 0.8 [2], 3.0 [3], 8.0 [4] |
 | 5-(4-Fluorophenyl)-2-[(4-methylsulfanylphenyl)methylsulfanyl]-4-pyridin-4-ylpyrimidine | IC50 | 7400.0 [1], 60000.0 [2], 100000.0 [3] |
 | 5-(4-Fluorophenyl)-2-[(4-methylsulfonylphenyl)methylsulfanyl]-4-pyridin-4-ylpyrimidine | IC50 | 7700.0 [1], 17800.0 [2], 100000.0 [3] |
 | 4-(4-Fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-5-pyridin-4-ylpyrimidine | IC50 | 17800.0 [1], 29900.0 [2], 100000.0 [3] |
 | 5-(4-Fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-4-pyridin-3-ylpyrimidine | IC50 | 54000.0 [1], 75500.0 [2], 100000.0 [3] |
 | 6-(4-Fluorophenyl)-7-[2-[[(2S)-1-methoxypropan-2-yl]amino]pyrimidin-4-yl]-2,3-dihydro-1H-pyrazolo[1,2-a]pyrazol-5-one | IC50 | 16.0 [1], 27.0 [2], 39.0 [3], 50.0 [4] |
 | 5-(4-Fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-4-pyridin-4-yl-1H-pyrimidin-6-one | IC50 | 25500.0 [1], 27000.0 [2], 100000.0 [3] |
 | Dasatinib | IC50 | 100.0 [1] |
 | Tpl2 Kinase Inhibitor | IC50 | 700.0 [1], 8500.0 [2], 180000.0 [3] |
 | 4-(4-Fluorophenyl)-5-(4-pyridyl)-1H-imidazole | IC50 | 170.0 [1], 210.0 [2], 10000.0 [3] |
 | 4-(3-Chloro-4-fluoro-phenylamino)-6-(2-morpholin-4-yl-ethylamino)-1,7-naphthyridine-3-carbonitrile | IC50 | 4500.0 [1], 6800.0 [2], 58000.0 [3] |
 | 4-[3-Methyl-2-piperidin-4-yl-5-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-N-[(1S)-1-phenylethyl]pyrimidin-2-amine | IC50 | 0.11 [1], 4.3 [2] |
 | 2-(2-(Methylsulfinyl)benzylthio)-5-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidine | IC50 | 2300.0 [1], 3200.0 [2], 5100.0 [3] |
 | {4-[5-(4-Fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]pyridin-2-yl}-phenylamine | IC50 | 30.0 [1], 130.0 [2], 340.0 [3] |
 | 4-[1-Methyl-2-piperidin-4-yl-5-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-N-[(1S)-1-phenylethyl]pyrimidin-2-amine | IC50 | 1220.0 [1], 12000.0 [2], 24000.0 [3] |
 | {4-[5-(4-Fluoro-phenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenyl-ethyl)-amine | IC50 | 41.0 [1], 170.0 [2], 340.0 [3] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]pyridin-2-amine | IC50 | 44.0 [1], 370.0 [2], 900.0 [3] |
 | 2-(Benzylthio)-4-(4-fluorophenyl)-5-(2-fluoro-4-pyridinyl)-1H-imidazole | IC50 | 2900.0 [1], 4200.0 [2], 40500.0 [3] |
 | Benzyl-{4-[5-(4-fluoro-phenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-amine | IC50 | 108.0 [1], 630.0 [2], 650.0 [3] |
 | 2-Fluoro-4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]pyridine | IC50 | 300.0 [1], 2800.0 [2], 3800.0 [3] |
 | 6-(2-Morpholinoethylamino)-4-(4-phenoxyphenylamino)-1,7-naphthyridine-3-carbonitrile | IC50 | 1400.0 [1], 14900.0 [2], 400000.0 [3] |
 | 4-[6-Morpholin-4-yl-3-[3-(trifluoromethyl)phenyl]pyridazin-4-yl]-N-[(1S)-1-phenylethyl]pyrimidin-2-amine | IC50 | 2.6 [1], 292.0 [2], 1200.0 [3] |
 | 4-[2-Benzylsulfanyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]-N-(1-phenylethyl)pyridin-2-amine | IC50 | 45.0 [1], 380.0 [2], 2700.0 [3] |
 | 4-[5-(4-Fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-1H-imidazol-4-yl]-N-(1-phenylethyl)pyridin-2-amine | IC50 | 40.0 [1], 270.0 [2], 910.0 [3] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine | IC50 | 56.0 [1], 640.0 [2], 790.0 [3] |
 | 5-(4-Fluorophenyl)-2-[(3-methylsulfinylphenyl)methylsulfanyl]-4-pyridin-4-ylpyrimidine | IC50 | 5400.0 [1], 6500.0 [2], 19000.0 [3] |
 | N-Benzyl-4-[5-(4-fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-1H-imidazol-4-yl]pyridin-2-amine | IC50 | 470.0 [1], 1450.0 [2], 2000.0 [3] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-N-(2-phenylethyl)pyridin-2-amine | IC50 | 31.0 [1], 240.0 [2], 350.0 [3] |
 | N-[(4-Chlorophenyl)methyl]-4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]pyridin-2-amine | IC50 | 150.0 [1], 500.0 [2], 950.0 [3] |
 | 4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanylimidazol-4-yl]pyridin-2-amine | IC50 | 270.0 [1], 2300.0 [2], 3200.0 [3] |
 | N-Benzyl-4-[2-benzylsulfanyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]pyridin-2-amine | IC50 | 200.0 [1], 1420.0 [2], 3200.0 [3] |
 | N-Benzyl-4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-N-methylpyridin-2-amine | IC50 | 2700.0 [1], 4600.0 [2], 8700.0 [3] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-N-[(4-methylphenyl)methyl]pyridin-2-amine | IC50 | 85.0 [1], 670.0 [2], 830.0 [3] |
 | 2-Fluoro-4-[5-(4-fluorophenyl)-2-[(4-methylsulfinylphenyl)methylsulfanyl]-1H-imidazol-4-yl]pyridine | IC50 | 2450.0 [1], 6900.0 [2], 9300.0 [3] |
 | N-[(3,4-Dichlorophenyl)methyl]-4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]pyridin-2-amine | IC50 | 230.0 [1], 700.0 [2], 720.0 [3] |
 | 4-(4-Benzylphenylamino)-6-(2-morpholinoethylamino)-1,7-naphthyridine-3-carbonitrile | IC50 | 800.0 [1], 13600.0 [2], 400000.0 [3] |
 | N-Benzyl-4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanylimidazol-4-yl]pyridin-2-amine | IC50 | 82.0 [1], 580.0 [2], 930.0 [3] |
 | 6-(2-Morpholinoethylamino)-4-(4-(phenylthio)phenylamino)-1,7-naphthyridine-3-carbonitrile | IC50 | 2700.0 [1], 20100.0 [2], 31000.0 [3] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-3-propylimidazol-4-yl]pyridine | IC50 | 360.0 [1], 1300.0 [2], 2200.0 [3] |
 | Doramapimod | IC50 | 8.0 [1], 9.0 [2] |
 | 4-[3-[4-(4-Fluorophenyl)-5-pyridin-4-ylimidazol-1-yl]propyl]morpholine | IC50 | 120.0 [1], 1300.0 [2] |
 | 4-(4-Fluorophenyl)-1-cycloropropylmethyl-5-(4-pyridyl)-imidazole | IC50 | 24.0 [1], 90.0 [2] |
 | 2-(4-Fluorophenyl)-4-methoxy-3-(pyridin-4-YL)-1H-pyrrolo[2,3-B]pyridin-6-amine | IC50 | 6.3 [1], 7.0 [2] |
 | 4-[(3-Chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile | IC50 | 2110.0 [1], 30000.0 [2] |
 | 4-[3-Methyl-2-piperidin-4-yl-5-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-N-[(1S)-1-phenylethyl]pyridin-2-amine | IC50 | 0.19 [1], 2.8 [2] |
 | N-[1-[(3-Fluorophenyl)methyl]indazol-5-yl]-5-[[(2S)-morpholin-2-yl]methoxymethyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine | IC50 | 50000.0 [1] |
 | 5-(2-Chlorophenyl)-1-(2,6-dichlorophenyl)-7-(piperidin-4-ylamino)-3,4-dihydroquinazolin-2(1H)-one | IC50 | 0.5 [1], 36.0 [2] |
 | 5-(2-Chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(1-propan-2-ylpiperidin-4-yl)-3,4-dihydroquinazolin-2-one | IC50 | 0.6 [1], 5.6 [2] |
 | 3-{5-[(2-Fluorophenyl)amino]-1h-Indazol-1-Yl}-N-(3,4,5-Trimethoxyphenyl)benzamide | IC50 | 30.0 [1] |
 | 2-Phenyl-4-[3-(trifluoromethyl)phenyl]-5-(4-pyridyl)-1H-imidazole | IC50 | 86.0 [1], 100000.0 [2] |
 | 1-(3-Morpholinopropyl)-4-(4-fluorophenyl)-5-(2-methyl-4-pyridyl)-1H-imidazole | IC50 | 2100.0 [1], 3050.0 [2] |
 | 4-(2,4-Diphenyl-1H-imidazol-5-yl)-N-methylpyrimidin-2-amine | IC50 | 120.0 [1], 100000.0 [2] |
 | 4-[3-[5-(2,6-Dimethylpyridin-4-yl)-4-(4-fluorophenyl)imidazol-1-yl]propyl]morpholine | IC50 | 17000.0 [1], 25000.0 [2] |
 | 6-[2-(2,4-Difluorophenyl)imidazo[1,2-a]pyridin-3-yl]-2-(2-methylphenyl)-4,5-dihydropyridazin-3-one | IC50 | 14.0 [1], 440.0 [2] |
 | 2-Chloro-4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]pyridine | IC50 | 350.0 [1], 2200.0 [2] |
 | 2-(Benzylthio)-4-(4-fluorophenyl)-5-(2-chloro-4-pyridinyl)-1H-imidazole | IC50 | 1800.0 [1], 60000.0 [2] |
 | {4-[(2-Aminophenyl)amino]phenyl}(Phenyl)methanone | IC50 | 159.0 [1], 226.0 [2] |
 | 2-(2,6-Dichlorophenyl)-6-[2-(2,4-difluorophenyl)imidazo[1,2-a]pyridin-3-yl]-4,5-dihydropyridazin-3-one | IC50 | 10.0 [1], 205.0 [2] |
 | 4-[3-Methyl-2-piperidin-4-yl-5-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-N-[(1R)-1-phenylethyl]pyrimidin-2-amine | IC50 | 1.5 [1], 50.0 [2] |
 | (2-Chloro-4-(phenylamino)phenyl)(o-tolyl)methanone | IC50 | 24.0 [1], 119.0 [2] |
 | [4-(2-Amino-phenylamino)-2-chloro-phenyl]-phenyl-methanone | IC50 | 214.0 [1], 437.0 [2] |
 | 6-[2-(2-Chloro-4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-2-(2-methylphenyl)-4,5-dihydropyridazin-3-one | IC50 | 22.0 [1], 220.0 [2] |
 | 6-[2-(2-Chloro-4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]-2-(2-methylphenyl)pyridazin-3-one | IC50 | 20.0 [1], 100.0 [2] |
 | N-[(1S)-1-Phenylethyl]-4-[2-piperidin-4-yl-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]pyrimidin-2-amine | IC50 | 0.75 [1], 6.0 [2] |
 | 6-[2-(2,3-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl]-2-(2-methylphenyl)pyridazin-3-one | IC50 | 6.0 [1], 500.0 [2] |
 | [4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyrimidin-2-yl]-(4-methoxy-benzyl)-amine | IC50 | 38.0 [1], 100000.0 [2] |
 | N-[(4-Methoxyphenyl)methyl]-4-[2-piperidin-4-yl-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]pyrimidin-2-amine | IC50 | 7.6 [1], 290.0 [2] |
 | 4-[2-Cyclohexyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl]-pyridine | IC50 | 34.0 [1], 70.0 [2] |
 | 4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyrimidin-2-ylamine | IC50 | 57.0 [1], 100000.0 [2] |
 | 4-[5-(4-Fluoro-phenyl)-2-piperidin-3-yl-3H-imidazol-4-yl]-pyridine | IC50 | 19.0 [1], 585.0 [2] |
 | N-[(1R)-1-Phenylethyl]-4-[2-piperidin-4-yl-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]pyrimidin-2-amine | IC50 | 0.4 [1], 0.97 [2] |
 | 4-[2-(4-Piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazole-5-yl]pyrimidine-2-amine | IC50 | 7.0 [1], 190.0 [2] |
 | 4-(2,5-Diphenyl-3H-imidazol-4-yl)-pyrimidine | IC50 | 700.0 [1], 100000.0 [2] |
 | 4-[5-(4-Fluorophenyl)-4-pyridin-4-yl-1H-imidazol-2-yl]piperidine | IC50 | 9.0 [1], 175.0 [2] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-2-methoxypyridine | IC50 | 150.0 [1], 1900.0 [2] |
 | 6-[2-(2,4-Difluorophenyl)imidazo[1,2-a]pyridin-3-yl]-2-(2-methylphenyl)pyridazin-3-one | IC50 | 68.0 [1], 870.0 [2] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]-1H-pyridin-2-one | IC50 | 500.0 [1], 3100.0 [2] |
 | 4-[5-(4-Fluorophenyl)-2-methylsulfanyl-3-propylimidazol-4-yl]pyridin-2-amine | IC50 | 500.0 [1], 5400.0 [2] |
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