Mas-related G-protein coupled receptor member X1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-[2-(Diphenylmethyl)-1-azabicyclo[2.2.2]oct-3-ylidene]-1-(2-methoxyphenyl)-ethanone	IC50	50.0 [1], 320.0 [2], 800.0 [3]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-[(3,5-dichloropyridin-4-yl)methyl]-N-(3-morpholin-4-ylpropyl)acetamide	IC50	14.0 [1], 50.0 [2]
	4-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymethyl)-benzonitrile	IC50	556.0 [1], 1850.0 [2]
	[(3R)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] N-(3-nitrophenyl)carbamate	IC50	290.0 [1], 1850.0 [2]
	[(3S)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] N-(2-chlorophenyl)carbamate	IC50	375.0 [1], 1180.0 [2]
	(3E)-2-Benzhydryl-3-(2-phenylethylidene)-1-azabicyclo[2.2.2]octane	IC50	163.0 [1], 1430.0 [2]
	[(3R)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] N-(2-chlorophenyl)carbamate	IC50	140.0 [1], 607.0 [2]
	(2E)-2-(2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-ylidene)-1-(4-fluorophenyl)ethanol	IC50	165.0 [1], 630.0 [2]
	[(3R)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] N-naphthalen-1-ylcarbamate	IC50	124.0 [1], 1220.0 [2]
	1-[(3R)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl]-3-(2-methoxyphenyl)thiourea	IC50	418.0 [1], 2510.0 [2]
	(2E)-2-(2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-ylidene)-1-(2-methoxyphenyl)ethanol	IC50	80.0 [1], 182.0 [2]
	[(3R)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] 2-(trifluoromethyl)benzoate	IC50	252.0 [1], 2400.0 [2]
	(3R)-2-Benzhydryl-N-[[2-(trifluoromethyl)phenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine	IC50	244.0 [1], 1290.0 [2]
	N-[2-(4-Chlorophenyl)ethyl]-4-pyrrolidin-1-ylquinazolin-2-amine	IC50	8060.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-(oxolan-2-ylmethyl)-N-(pyridin-4-ylmethyl)acetamide	IC50	40.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-(3-methoxypropyl)-N-(pyridin-4-ylmethyl)acetamide	IC50	88.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-[(3,5-dichloropyridin-4-yl)methyl]-N-(pyridin-4-ylmethyl)acetamide	IC50	24.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-(cyclopropylmethyl)-N-(pyridin-4-ylmethyl)acetamide	IC50	295.0 [1]
	N-[(3-Bromopyridin-4-yl)methyl]-2-[4-[2-[2-(4-chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-ethylacetamide	IC50	108.0 [1]
	4-(2-(2-(4-Chlorophenethylamino)quinazolin-4-ylamino)ethyl)benzenesulfonamide	IC50	640.0 [1]
	4-(2-(2-(4-Chlorophenethylamino)pyrimidin-4-ylamino)ethyl)benzenesulfonamide	IC50	301.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-1-piperidin-1-ylethanone	IC50	758.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-(furan-2-ylmethyl)-N-(pyridin-4-ylmethyl)acetamide	IC50	20.0 [1]
	N-Benzyl-2-[4-[2-[2-(4-chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-(pyridin-4-ylmethyl)acetamide	IC50	22.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-ethyl-N-(pyridin-4-ylmethyl)acetamide	IC50	244.0 [1]
	1-[2-[2-(4-Chlorophenyl)ethylamino]-4-pyrrolidin-1-ylquinazolin-6-yl]sulfonyl-N-[1-(dimethylamino)propan-2-yl]piperidine-4-carboxamide	IC50	530.0 [1]
	N-Benzyl-2-[4-[2-[2-(4-chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-ethylacetamide	IC50	330.0 [1]
	2-[4-[2-[2-(4-Chlorophenyl)ethylamino]pyrimidin-4-yl]piperazin-1-yl]-N-[(3,5-dichloropyridin-4-yl)methyl]-N-ethylacetamide	IC50	77.0 [1]
	(2E)-2-(2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-ylidene)-1-[3-(trifluoromethyl)phenyl]ethanol	IC50	90.0 [1]
	[(3S)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] 3,4-dimethoxybenzoate	IC50	64.0 [1]
	(2E)-2-(2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-ylidene)-1-(3,5-dimethylphenyl)ethanol	IC50	200.0 [1]
	3-[[(3R)-2-Benzhydryl-1-azabicyclo[2.2.2]octan-3-yl]oxymethyl]benzonitrile	IC50	209.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 32 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Mas-related G-protein coupled receptor member X1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/mas-related-g-protein-coupled-receptor-member-x1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Mas-related G-protein coupled receptor member X1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mas-related-g-protein-coupled-receptor-member-x1-inhibitors-ic50-ki.
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