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Matrix metalloproteinase 16 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
IlomastatIC508.0 [1]
CID 6914621Ki1599.0 [1]
(3R,4R)-N-Hydroxy-4-[[4-[[2-(trifluoromethyl)benzimidazol-1-yl]methyl]benzoyl]amino]oxane-3-carboxamideKi10000.0 [1]
(8S,11R,12S)-12-N-Hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
N-[4-[2-(Hydroxyamino)-2-oxoethyl]oxan-4-yl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideKi5554.0 [1]
MarimastatIC5010000.0 [1]
(2R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methylbutanamide;hydrochlorideIC506.8 [1]
N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamideIC50900.0 [1]
(R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamideIC5051.0 [1]
2-[[2-(Hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]acetic acidIC50996.0 [1]
2-[[2-(Hydroxyamino)-2-oxoethyl]-(4-phenoxyphenyl)sulfonylamino]-N-[2-(4-sulfamoylphenyl)ethyl]acetamideIC501.0 [1]
2-[[(2R)-1-(Hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-phenoxyphenyl)sulfonylamino]acetic acidIC501.56 [1]
2-[[2-(Hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]-N-[2-(4-sulfamoylphenyl)ethyl]acetamideIC5044.0 [1]
2-[(Biphenyl-4-sulfonyl)-hydroxycarbamoylmethyl-amino]-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamideIC50186.0 [1]
N,6-Dihydroxy-2-(4-nitrophenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC50177.0 [1]
(2R)-N-Hydroxy-2-methyl-2-methylsulfonyl-4-(4-phenylphenyl)butanamideKi10000.0 [1]
CID 10160968Ki5554.0 [1]
(6S,7R,10S)-6-N-Hydroxy-10-N-[2-(methylamino)-2-oxoethyl]-7-(2-methylpropyl)-8-oxo-2-oxa-9-azabicyclo[10.2.2]hexadeca-1(14),12,15-triene-6,10-dicarboxamideKi35.0 [1]
6-(Benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5022.0 [1]
{[4-Phenoxy-benzenesulphonyl]-hydroxycarbamoylmethyl-amino}-acetic acidIC5011.4 [1]
4-[[5-[2-[(4-Fluorophenyl)methylcarbamoyl]-6-methylpyridin-4-yl]tetrazol-2-yl]methyl]cyclohexane-1-carboxylic acidKi25000.0 [1]
(2R)-2-[[4-[4-[(4-Chlorophenyl)methoxy]phenyl]phenyl]sulfonyl-propan-2-yloxyamino]-N-hydroxy-3-methylbutanamideIC505000.0 [1]
6-(Benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5056.0 [1]
6-(Benzyloxy)-N-hydroxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5035.0 [1]
N,6-Dihydroxy-2-tosyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5021.0 [1]
2-(Benzenesulfonyl)-N,6-dihydroxy-3,4-dihydro-1H-isoquinoline-1-carboxamideIC50184.0 [1]
N,6-Dihydroxy-7-methoxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5016.0 [1]
N,6-Dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5040.0 [1]
2-(2,5-Dichlorophenylsulfonyl)-N,6-dihydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC501839.0 [1]
N-Hydroxy-2-(2-(4-methoxyphenylsulfonyl)phenyl)acetamideIC50130.0 [1]
N-Hydroxy-2-[2-[4-(4-methoxyphenyl)phenyl]sulfonylphenyl]acetamideIC50130.0 [1]
2-[2-[4-(4-Methoxyphenyl)phenyl]sulfonylphenyl]ethanoic acidIC50730.0 [1]
(8S,11R,12S)-12-N-Hydroxy-11-(2-methylpropyl)-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi107.0 [1]
(8S,11R,12S)-12-N-Hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
N-Hydroxy-2-(4-phenoxy-benzenesulfonyl)benzamideIC501300.0 [1]
Tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[[4-[(2-methylbenzimidazol-1-yl)methyl]benzoyl]amino]pyrrolidine-1-carboxylateKi5554.0 [1]
Tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[[4-[(2-methylsulfanylbenzimidazol-1-yl)methyl]benzoyl]amino]pyrrolidine-1-carboxylateKi5454.0 [1]
Tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[[4-[(2-propan-2-ylbenzimidazol-1-yl)methyl]benzoyl]amino]pyrrolidine-1-carboxylateKi5554.0 [1]
(8S,11R,12S)-8-N-(2-Amino-2-oxoethyl)-12-N-hydroxy-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
3-(4-(2-Phenylethynyl)benzoyl)pentanoic acidIC5032040.0 [1]
(8S,11R,12S)-11-[[4-[3,5-Bis(trifluoromethyl)phenyl]phenyl]methyl]-12-N-hydroxy-2,10-dioxo-8-N-(2-oxo-2-piperazin-1-ylethyl)-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi2000.0 [1]
(2R)-N-Hydroxy-3-methyl-2-[[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]-(4-phenoxyphenyl)sulfonylamino]butanamideIC500.31 [1]
2-[[4-[4-[(4-Chlorophenyl)methoxy]phenyl]phenyl]sulfonyl-propan-2-yloxyamino]-N-hydroxyacetamideIC5015000.0 [1]
N-Hydroxy-2-{2-[4-(4-methoxy-phenoxy)benzenesulfonyl]-phenyl}acetamideIC5032.0 [1]
2-(4-Aminophenyl)sulfonyl-N,6-dihydroxy-3,4-dihydro-1H-isoquinoline-1-carboxamideIC50202.0 [1]
2-(2,5-Dichlorophenyl)sulfonyl-N-hydroxy-6-phenylmethoxy-3,4-dihydro-1H-isoquinoline-1-carboxamideIC504633.0 [1]
N,6-Dihydroxy-2-(4-methoxyphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-1-carboxamideIC501677.0 [1]
N-Hydroxy-2-[4-(4-methoxy-phenoxy)benzenesulfonyl]benzamideIC506000.0 [1]
2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamideIC505100.0 [1]
N-Hydroxy-2-[2-[4-(4-methoxyphenyl)phenyl]sulfonylphenyl]propanamideIC50150.0 [1]
{2-[4-(4-Methoxy-phenoxy)benzenesulfonyl]phenyl}acetic AcidIC506500.0 [1]
N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamideIC5031000.0 [1]
N-Hydroxy-2-[4-(4-methylsulfinylphenoxy)phenyl]sulfonylbenzamideIC50110000.0 [1]
N-Hydroxy-2-[4-(4-methoxyphenyl)phenyl]sulfonylbenzamideIC501200.0 [1]
2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetamideIC50220.0 [1]
N-Hydroxy-2-[2-(4-phenylphenyl)sulfonylphenyl]propanamideIC50470.0 [1]
2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic AcidIC5093000.0 [1]
[2-(Biphenyl-4-sulfonyl)phenyl]acetic AcidIC504300.0 [1]
2-[2-(4-Phenylphenyl)sulfonylphenyl]propanoic acidIC506300.0 [1]
2-[2-[4-(4-Methoxyphenyl)phenyl]sulfonylphenyl]propanoic acidIC501100.0 [1]
N-Hydroxy-3-methyl-2-[propan-2-yloxy-[4-(4-propan-2-ylphenyl)phenyl]sulfonylamino]butanamideIC5051.0 [1]
(2R)-3-Methyl-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butanoic acidIC5018000.0 [1]
(3R)-1-Hydroxy-4-(4-phenoxyphenyl)sulfonyl-3-propan-2-ylpiperazine-2,6-dioneIC5039.0 [1]
(3R)-1-Hydroxy-4-(4-phenylphenyl)sulfonyl-3-propan-2-ylpiperazine-2,6-dioneIC502200.0 [1]
(3R)-1-Hydroxy-4-(4-methoxyphenyl)sulfonyl-3-propan-2-ylpiperazine-2,6-dioneIC501100.0 [1]
Items per page: 1 - 10 of 65
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References

This online tool may be cited as follows

MLA

"Quest Database™ Matrix metalloproteinase 16 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/matrix-metalloproteinase-16-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Matrix metalloproteinase 16 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/matrix-metalloproteinase-16-inhibitors-ic50-ki.
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