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Matrix metalloproteinase 7 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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Standard Type
▲
▼
Standard Values (in nM)
▲
▼
(2R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methylbutanamide;hydrochlorideIC50106.0 [1]
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamideIC50210.0 [1], 3100.0 [2]
4-[4-(4-Chloro-phenoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-carboxylic acid hydroxyamideKi1200.0 [1]
MarimastatIC504.1 [1], 11.0 [2], 20.0 [3], 10000.0 [4]
PrinomastatIC5054.0 [1], 72.0 [2], 91.0 [3]
PrinomastatKi54.0 [1]
N-(3-Methoxybenzyl)-4-Oxo-3,4-Dihydroquinazoline-2-CarboxamideIC5010000.0 [1]
2-((4-Phenoxyphenylsulfonyl)methyl)thiiraneKi96000.0 [1]
CID 6914621Ki259.0 [1]
Mmp inhibitor IIIC5030.0 [1]
Mmp inhibitor IIKi30.0 [1]
(2S)-2-[[4-(4-Methoxyphenyl)phenyl]sulfonylamino]-3-methylbutanoic acidIC507200.0 [1], 10000.0 [2]
Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-CarboxylateIC5030000.0 [1], 100000.0 [2]
BatimastatIC502.4 [1], 6.0 [2]
N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamideIC5050000.0 [1]
N-[(2S)-1-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-3-[4-[4-(trifluoromethoxy)phenyl]phenoxy]propan-2-yl]-N-hydroxyformamideIC5010000.0 [1]
N-Hydroxy-1-(2-methoxyethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpiperidine-4-carboxamideIC507000.0 [1]
N-Hydroxy-1-(2-methoxyethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpiperidine-4-carboxamideKi7000.0 [1]
4-{[1-Methyl-2,4-Dioxo-6-(3-Phenylprop-1-Yn-1-Yl)-1,4-Dihydroquinazolin-3(2h)-Yl]methyl}benzoic AcidIC5030000.0 [1]
(3R,4R)-N-Hydroxy-4-[[4-[[2-(trifluoromethyl)benzimidazol-1-yl]methyl]benzoyl]amino]oxane-3-carboxamideKi10000.0 [1]
(2S)-2-[[4-(4-Fluorophenyl)phenyl]sulfonylamino]-3-methylbutanoic acidIC504800.0 [1]
(8S,11R,12S)-12-N-Hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-11-[[4-[2-(trifluoromethyl)phenyl]phenyl]methyl]-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamideKi834.0 [1]
N-Hydroxy-1-(4-methoxyphenyl)sulfonylpiperazine-2-carboxamideIC502390.0 [1]
((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)valineIC507500.0 [1]
(3S)-N-Hydroxy-4-(4-methoxyphenyl)sulfonyl-2,2-dimethyl-1,1-dioxo-1,4-thiazepane-3-carboxamideIC5041.0 [1]
2-Pyrimidinecarboxamide, hexahydro-N-hydroxy-1,3-bis((4-methoxyphenyl)sulfonyl)-IC50460.0 [1]
N-(4-(4-(Thiiran-2-ylmethylsulfonyl)phenoxy)phenyl)acetamideKi39000.0 [1]
4-(4-(Thiiran-2-ylmethylsulfonyl)phenoxy)phenyl methanesulfonateKi18000.0 [1], 18200.0 [2]
N,6-Dihydroxy-2-(4-nitrophenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5021379.62 [1], 21420.0 [2]
N-[4-[2-(Hydroxyamino)-2-oxoethyl]oxan-4-yl]-4-[(2-methylquinolin-4-yl)methoxy]benzamideKi25.0 [1]
(S)-N-Hydroxy-4-(4-methoxyphenylsulfonyl)-2,2-dimethyl-1,4-thiazepane-3-carboxamideIC5030.0 [1]
N-Hydroxy-4-(4-methoxyphenyl)sulfonylthiomorpholine-3-carboxamideIC502027.0 [1], 2070.0 [2]
(7S,8R,11S)-7-N-Hydroxy-11-N-methyl-8-(2-methylpropyl)-9-oxo-2-oxa-10-azabicyclo[11.2.2]heptadeca-1(15),13,16-triene-7,11-dicarboxamideIC501.6 [1]
4-[(2-Methylquinolin-4-yl)methoxy]-N-[[5-(4-methylsulfonylpiperazin-1-yl)-2,4,6-trioxo-1,3-diazinan-5-yl]methyl]benzamideKi6370.0 [1]
6-(Benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC502398.83 [1], 2424.0 [2]
4-((2-Methylquinolin-4-yl)methoxy)-N-(2-(2-oxo-2,3-dihydro-1H-imidazole-5-carbonyl)phenyl)benzamideKi636.0 [1], 6368.0 [2]
4-[2-[[6-Fluoro-2-[(3-methoxyphenyl)methylcarbamoyl]-4-oxo-3H-quinazolin-5-yl]oxy]ethyl]benzoic acidIC5010000.0 [1]
3-{[4-(But-2-Yn-1-Yloxy)phenyl]sulfonyl}propane-1-ThiolKi2500.0 [1]
(3R,4R)-N-Hydroxy-4-[[4-[[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]methyl]benzoyl]amino]oxane-3-carboxamideKi6368.0 [1]
5-(2-Amino-2-oxoethyl)-4-oxo-N-[(3-oxo-4H-1,4-benzoxazin-6-yl)methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidine-2-carboxamideIC502500.0 [1], 10000.0 [2]
(8S,9R,12S)-8-N-Hydroxy-12-N-methyl-9-(2-methylpropyl)-10-oxo-2-oxa-11-azabicyclo[12.2.2]octadeca-1(16),14,17-triene-8,12-dicarboxamideIC502.6 [1], 6.1 [2]
(2S,3R)-N-Hydroxy-3-(2-methylpropyl)-N'-[(2S)-1-(1,3-oxazol-2-yl)-1-oxo-3-phenylpropan-2-yl]-2-prop-2-enylbutanediamideIC504.2 [1]
6-(Benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5012022.64 [1], 12040.0 [2]
6-(Benzyloxy)-N-hydroxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC507079.46 [1], 7136.0 [2]
N,6-Dihydroxy-2-tosyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5010471.29 [1], 10500.0 [2]
N,6-Dihydroxy-7-methoxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC503162.28 [1], 3192.0 [2]
N,6-Dihydroxy-7-methoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5010690.0 [1], 10715.19 [2]
2-(2,5-Dichlorophenylsulfonyl)-N,6-dihydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamideIC5021379.62 [1], 21380.0 [2]
(6S,7S)-N-Hydroxy-5-methyl-6-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl]-5-azaspiro[2.5]octane-7-carboxamideIC505000.0 [1]
(6S,7S)-N-Hydroxy-5-methyl-6-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl]-5-azaspiro[2.5]octane-7-carboxamideKi75.0 [1]
(2R,3R)-4-[(2R)-2-(3-Chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyrazol-1-ylphenyl)ethyl]butanamideKi3769.0 [1], 3800.0 [2]
N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl-[2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethyl]amino]acetamideKi2000.0 [1]
(-)-Epigallocatechin gallateIC5021500.0 [1]
IlomastatIC5033.0 [1]
N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acidKi13000.0 [1]
(2S,3R)-N-Hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-prop-2-enylbutanediamideIC5011.0 [1]
(S)-2-(4'-Bromo-[1,1'-biphenyl]-4-ylsulfonamido)-3-methylbutanoic acidIC507200.0 [1]
Epigallocatechin 3-O-(3-O-methyl)gallateIC5020000.0 [1]
CipemastatIC5018.5 [1]
2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amideIC50100000.0 [1]
CID 9847838IC50466.0 [1]
n-[3-(n'-Hydroxycarboxamido)-2-(2-methylpropyl)-propanoyl]-o-tyrosine-n-methylamideIC5030.0 [1]
Unii-cdl03A411TIC501000.0 [1]
(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acidIC5010000.0 [1]
Unii-Q56UE7E40YIC505000.0 [1]
N-Hydroxy-N~2~-[(4-Methoxyphenyl)sulfonyl]glycinamideKi4000.0 [1]
N-[(1S)-1-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamideIC5011000.0 [1]
(R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamideIC5011111.0 [1]
D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]-IC501000.0 [1]
Methylamino-phenylalanyl-leucyl-hydroxamic acidIC508.3 [1]
Grassystatin AIC505000.0 [1]
(4S)-5-Amino-4-[[(2S)-2-[[(2S)-2-[[(4-bromophenyl)-hydroxyphosphoryl]methyl]-3-[3-[4-(3-chlorophenyl)phenyl]-1,2-oxazol-5-yl]propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoic acidKi626.0 [1]
5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trioneIC5050000.0 [1]
N-Phenyl-4-[(4h-1,2,4-Triazol-3-Ylsulfanyl)methyl]-1,3-Thiazol-2-AmineIC5010000.0 [1]
2-(Biphenyl-4-ylsulfonamido)-N-hydroxyacetamideKi5000.0 [1]
2-(Benzenesulfonamido)-N-hydroxyacetamideKi4000.0 [1]
N-Hydroxy-4-(4-phenylsulfanylphenyl)sulfonyl-1-prop-2-ynylpiperidine-4-carboxamideIC5010000.0 [1]
(6S,7R,10S)-6-N-Hydroxy-10-N-methyl-7-(2-methylpropyl)-8-oxo-2-oxa-9-azabicyclo[10.2.2]hexadeca-1(14),12,15-triene-6,10-dicarboxamideIC503.0 [1]
4-Benzoyl-N-hydroxy-1-(4-methoxyphenylsulfonyl)piperazine-2-carboxamideIC501522.0 [1]
(2R)-2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acidIC5011000.0 [1]
(2R)-2-[[4-(4-Bromophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylbutanamideIC50140.0 [1]
4-[4-(Thiirane-2-ylmethylsulfonyl)phenoxy]phenolKi31000.0 [1]
(2R,3S)-2-[(4-But-2-ynoxyphenyl)sulfonylamino]-N,3-dihydroxybutanamideIC50961.0 [1]
(2S)-3-Methyl-2-[(4-phenylphenyl)sulfonylamino]butanoic acidIC5071000.0 [1]
(2S)-2-[[8-(Methoxycarbonylamino)dibenzofuran-3-yl]sulfonylamino]-3-methylbutanoic acidIC5022.0 [1]
4''-Methylepigallocatechin gallateIC5072000.0 [1]
N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-benzyloxycarbonylpiperazine-2-carboxamideIC50232.0 [1]
Hydroxamate analogue 22IC50180.0 [1]
1-Cyclopropyl-N-hydroxy-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpiperidine-4-carboxamideIC507000.0 [1]
N-Hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamideIC5010000.0 [1]
1-Benzyl-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamideIC50925.0 [1]
MMP-9/MMP-13 Inhibitor IIC50931.0 [1]
4-Acetyl-N-hydroxy-1-(4-methoxyphenylsulfonyl)piperazine-2-carboxamideIC50821.0 [1]
4-(Furan-2-carbonyl)-N-hydroxy-1-(4-methoxyphenylsulfonyl)piperazine-2-carboxamideIC50642.0 [1]
4-(Cyclohexanecarbonyl)-N-hydroxy-1-(4-methoxyphenylsulfonyl)piperazine-2-carboxamideIC502173.0 [1]
N-Hydroxy-1-(4-methoxyphenylsulfonyl)-4-(2-phenoxyacetyl)piperazine-2-carboxamideIC50908.0 [1]
N-Hydroxy-1-(4-methoxyphenylsulfonyl)-4-(thiophene-2-carbonyl)piperazine-2-carboxamideIC50710.0 [1]
N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)piperazine-2-carboxamideIC5022050.0 [1]
4-Hexanoyl-N-hydroxy-1-(4-methoxyphenylsulfonyl)piperazine-2-carboxamideIC50787.0 [1]
L-Valine,N-[(4'-nitro[1,1'-biphenyl]-4-yl)sulfonyl]-IC505600.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Matrix metalloproteinase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/matrix-metalloproteinase-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Matrix metalloproteinase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/matrix-metalloproteinase-7-inhibitors-ic50-ki.
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