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MBT domain-containing protein 1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
(5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanoneIC5010000.0 [1], 30000.0 [2], 300000.0 [3]
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)IC509000.0 [1], 78000.0 [2]
1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)IC504900.0 [1], 50000.0 [2]
ChlorpheniramineIC5034000.0 [1]
OxybutyninIC50100000.0 [1]
MaprotilineIC5031000.0 [1]
BifemelaneIC50100000.0 [1]
4-Methyl-N-[3-(1-pyrrolidinyl)propyl]benzenesulfonamideIC5059000.0 [1]
6-Bromo-3-(4-chlorophenyl)-N-[3-(dimethylamino)propyl]-4-hydroxy-2-oxo-1H-quinazoline-4-carboxamideIC5037000.0 [1]
N,N-Dimethyl-4-(1-methyl-9H-pyrido[3,4-b]indol-4-yl)butan-1-amineIC5073000.0 [1]
1-(N-Methylamino)-4-phenylbutaneIC50100000.0 [1]
1,4-Bis(4-(pyrrolidinyl)piperidinyl)benzamideIC5010000.0 [1]
4-(2-Methoxy-4-methylphenoxy)-N-methylbutan-1-amineIC50100000.0 [1]
4-(4-Chloro-3-ethylphenoxy)-N-methylbutan-1-amineIC50100000.0 [1]
4-(4-Benzylphenoxy)-N-methylbutan-1-amineIC50100000.0 [1]
1-(1-(4-Chlorophenethyl)piperidin-4-yl)-N-methylmethanamineIC50100000.0 [1]
1-(7-Bromo-3,4-dihydro-2H-1,5-benzodioxepin-8-yl)-3-(dimethylamino)propan-1-oneIC50100000.0 [1]
2-Isopropyl-5-(methylamino)-2-o-tolylpentanenitrileIC50100000.0 [1]
3-Chloro-N-(3-(diethylamino)propyl)-4-fluorobenzenesulfonamideIC50100000.0 [1]
2-(3-(4-Chlorophenyl)isochroman-1-yl)-N-methylethanamineIC50100000.0 [1]
3-(11h-Dibenzo[b,f][1,4]oxathiepin-11-yl)-n-methylpropan-1-amineIC50100000.0 [1]
1-Phenyl-4-pyrrolidin-1-ylpiperidineIC5058000.0 [1]
UNC 926 hydrochlorideIC5030000.0 [1]
(3-Bromophenyl)-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC509200.0 [1]
4-(Dimethylamino)butan-2-yl 5-(1-phenylethyl)furan-2-carboxylateIC5066000.0 [1]
4-(Pyrrolidin-1-Yl)-1-{4-[2-(Pyrrolidin-1-Yl)ethyl]phenyl}piperidineIC5053000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)furan-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)thiophen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-(Benzylamino)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Benzyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC506800.0 [1]
[3-Phenoxy-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC509300.0 [1]
[3-Phenyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
2-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC503500.0 [1]
3-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC505100.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[3-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[2-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3,4-Bis(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylphenyl]methanoneIC505400.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanoneIC508200.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-[(4-pyrrolidin-1-ylpiperidin-1-yl)methyl]phenyl]methanoneIC508100.0 [1]
(4-Piperidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(Azepan-1-yl)piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC509700.0 [1]
[4-(4-Morpholin-4-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Cyclohexylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC508100.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpyrrolidin-1-ium-1-yl)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC505500.0 [1]
(4-Piperidin-4-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(4-Cyclopentylpiperazine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpiperidin-4-yl)piperazine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[1-(4-Methylpiperazin-1-yl)ethyl]piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylazepan-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(3-Pyrrolidin-1-ylazetidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(3-pyrrolidin-1-ylpyrrolidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)-N-(3-pyrrolidin-1-ylpropyl)benzamideIC5010000.0 [1]
[4-(2,7-Diazaspiro[3.4]octane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,7-Diazaspiro[4.4]nonane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,8-Diazaspiro[4.5]decane-8-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-7-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylazepane-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylazepan-1-yl)methanoneIC5010000.0 [1]
[4-[4-(Azetidin-1-yl)piperidine-1-carbonyl]phenyl]-[4-(azetidin-1-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-2-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC504000.0 [1]
[4-[4-(1-Methylpyrrolidin-2-yl)piperidine-1-carbonyl]phenyl]-[4-(1-methylpyrrolidin-2-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanoneIC5010000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)pyridin-3-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Nitro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Amino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[2,3,5,6-tetrafluoro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[2,5-Dimethyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-1-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC505700.0 [1]
(3-Bromophenyl)-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5030000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)benzamideIC5010000.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5010000.0 [1]
[3-Bromo-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC507800.0 [1]
7-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-1,4-dioxa-7-azaspiro[4.4]nonaneIC50300000.0 [1]
6-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-2-oxa-6-azaspiro[3.3]heptaneIC50247000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]pyrrolidine-3-carbonitrileIC50300000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azepaneIC50249000.0 [1]
1-[3-Chloro-4-(2-pyrrolidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidineIC50176000.0 [1]
4-Piperidin-1-yl-1-[4-(2-pyrrolidin-1-ylethyl)phenyl]piperidineIC50170000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(3-pyrrolidin-1-ylpropyl)phenyl]piperidineIC50135000.0 [1]
4-Pyrrolidin-1-yl-1-[3-(2-pyrrolidin-1-ylethyl)phenyl]piperidineIC50261000.0 [1]
[3-(Hydroxymethyl)-1-[2-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azetidin-3-yl]methanolIC50300000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(pyrrolidin-1-ylmethyl)phenyl]piperidineIC50157000.0 [1]
1-[[4-(2-Pyrrolidin-1-ylethyl)phenyl]methyl]pyrrolidineIC5094000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]piperidineIC50149000.0 [1]
4-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]morpholineIC50300000.0 [1]
1-[4-[2-(Azetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidineIC50300000.0 [1]
1-[4-[2-(3,3-Difluoroazetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidineIC50300000.0 [1]
1-[4-(2-Piperidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidineIC50290000.0 [1]
4-Pyrrolidin-1-yl-1-[3-(pyrrolidin-1-ylmethyl)phenyl]piperidineIC5078000.0 [1]
1-Pyrrolidin-1-yl-3-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]propan-1-oneIC50300000.0 [1]
Pyrrolidin-1-yl-[3-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanoneIC50300000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]pyrrolidin-3-oneIC50166000.0 [1]
N-(3-(Diethylamino)propyl)-2,5-dimethoxybenzenesulfonamideIC50100000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ MBT domain-containing protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/mbt-domain-containing-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ MBT domain-containing protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mbt-domain-containing-protein-1-inhibitors-ic50-ki.
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