Melanin-concentrating hormone receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2-(4-(Benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-6-yl)acetamide	IC50	11.0 [1]
	7-Fluorochromone-2-carboxamide	IC50	29.0 [1]
	6-Benzyloxymethyl-5-[4-(4-chloro-benzylamino)-phenyl]-pyrimidine-2,4-diamine	IC50	10000.0 [1]
	N-(4-Phenoxyphenyl)-N'-[1-(2-pyrrolidin-1-ylethyl)-1H-indazol-5-yl]urea	IC50	104.0 [1]
	MCHr1 antagonist 2	IC50	25.0 [1]
	N-(1-(4-Acetamidobenzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide	IC50	10000.0 [1]
	1-(2-{5-[3-(4-Phenoxy-phenyl)-ureido]-indazol-1-yl}-ethyl)-piperidine-4-carboxylic acid amide	IC50	171.0 [1]
	1-(4-Phenoxy-benzyl)-3-[1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]-urea	IC50	626.0 [1]
	1-[1-[2-[(2S)-2-(Methoxymethyl)pyrrolidin-1-yl]ethyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	516.0 [1]
	1-[2-(4-Phenoxyphenyl)ethyl]-3-[1-(2-pyrrolidin-1-ylethyl)indazol-6-yl]urea	IC50	178.0 [1]
	N-(1-((1H-Indol-6-yl)methyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide	IC50	66.0 [1]
	N-(1-(Benzo[b]thiophen-5-ylmethyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide	IC50	57.0 [1]
	1-(4-Benzyloxy-phenyl)-3-[1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]-urea	IC50	7140.0 [1]
	1-(4-Phenoxyphenyl)-3-[1-(2-pyrrolidin-1-ylethyl)-1H-indazol-5-yl]imidazolidin-2-one	IC50	1120.0 [1]
	7-Fluoro-N-[1-[(1-methyl-2-oxoquinolin-7-yl)methyl]piperidin-4-yl]-4-oxochromene-2-carboxamide	IC50	44.0 [1]
	7-Fluoro-4-oxo-N-(1-((2-oxo-2H-chromen-7-yl)methyl)piperidin-4-yl)-4H-chromene-2-carboxamide	IC50	46.0 [1]
	N-(1-((1H-Indol-5-yl)methyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide	IC50	110.0 [1]
	1-(4-Phenoxy-phenyl)-3-[1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-5-yl]-1,3-dihydro-imidazol-2-one	IC50	654.0 [1]
	N-(1-(Benzo[d]oxazol-6-ylmethyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide	IC50	106.0 [1]
	N-[1-(6-Acetamido-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide	IC50	10000.0 [1]
	N-(1-(Benzofuran-5-ylmethyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide	IC50	35.0 [1]
	7-Fluoro-4-oxo-N-[1-[(2-oxo-1H-quinolin-7-yl)methyl]piperidin-4-yl]chromene-2-carboxamide	IC50	162.0 [1]
	N-[1-(6,7-Dihydro-5H-cyclopenta[f][1,3]benzodioxol-7-yl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide	IC50	10000.0 [1]
	1-[1-[3-(Cyclopentylamino)propyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	275.0 [1]
	1-[3-[5-[(4-Phenoxyphenyl)carbamoylamino]indazol-1-yl]propyl]piperidine-4-carboxamide	IC50	2880.0 [1]
	1-[1-[2-(4-Hydroxypiperidin-1-yl)ethyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	10000.0 [1]
	1-[2-(4-Phenoxyphenyl)ethyl]-3-[1-(2-pyrrolidin-1-ylethyl)indazol-5-yl]urea	IC50	10000.0 [1]
	1-(4-Phenoxyphenyl)-3-[1-(2-pyrrolidin-1-ylethyl)indazol-4-yl]urea	IC50	10000.0 [1]
	1-(4-Phenoxyphenyl)-3-[1-(2-pyrrolidin-1-ylethyl)indazol-6-yl]urea	IC50	10000.0 [1]
	1-(4-Phenylmethoxyphenyl)-3-[1-(2-pyrrolidin-1-ylethyl)indazol-5-yl]urea	IC50	10000.0 [1]
	1-[1-[3-[(2S)-2-(Methoxymethyl)pyrrolidin-1-yl]propyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	1177.0 [1]
	1-(4-Phenylmethoxyphenyl)-3-[1-(2-pyrrolidin-1-ylethyl)indazol-4-yl]urea	IC50	10000.0 [1]
	1-[(4-Phenoxyphenyl)methyl]-3-[1-(2-pyrrolidin-1-ylethyl)indazol-5-yl]urea	IC50	10000.0 [1]
	1-[1-[2-(2-Methylpropylamino)ethyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	751.0 [1]
	1-[1-[3-(4-Hydroxypiperidin-1-yl)propyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	894.0 [1]
	1-[1-[2-(3,3-Difluoropyrrolidin-1-yl)ethyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	10000.0 [1]
	1-(1-Benzylpiperidin-4-yl)-3-[1-(2-pyrrolidin-1-ylethyl)indazol-6-yl]urea	IC50	10000.0 [1]
	1-(1-Benzylpiperidin-4-yl)-3-[1-(2-pyrrolidin-1-ylethyl)indazol-5-yl]urea	IC50	10000.0 [1]
	1-[1-[2-(Cyclopentylamino)ethyl]indazol-5-yl]-3-(4-phenoxyphenyl)urea	IC50	147.0 [1]
	2-[(4-Phenoxyphenyl)methylamino]-N-[1-(2-pyrrolidin-1-ylethyl)indol-6-yl]acetamide	IC50	1810.0 [1]
	N-[1-(7,8-Dihydro-6H-cyclopenta[g][1,3]benzodioxol-6-yl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide	IC50	2750.0 [1]
	7-Fluoro-4-oxo-N-[1-(2-oxo-3,5,6,7-tetrahydrocyclopenta[f][1,3]benzoxazol-5-yl)piperidin-4-yl]chromene-2-carboxamide	IC50	173.0 [1]
	7-Fluoro-4-oxo-N-[1-(3-oxo-4,6,7,8-tetrahydrocyclopenta[g][1,4]benzoxazin-6-yl)piperidin-4-yl]chromene-2-carboxamide	IC50	95.0 [1]
	N-[1-[(2-Ethyl-1,3-benzoxazol-6-yl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide	IC50	10000.0 [1]
	N-[1-[(2-Ethyl-1,3-benzoxazol-5-yl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide	IC50	1380.0 [1]
	7-Fluoro-4-oxo-N-[1-[(2-oxo-3H-1,3-benzoxazol-5-yl)methyl]piperidin-4-yl]chromene-2-carboxamide	IC50	569.0 [1]
	7-Fluoro-4-oxo-N-[1-[(2-oxo-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]chromene-2-carboxamide	IC50	5590.0 [1]
	7-Fluoro-4-oxo-N-[1-[(3-oxo-4H-1,4-benzoxazin-7-yl)methyl]piperidin-4-yl]chromene-2-carboxamide	IC50	2410.0 [1]
	N-[1-[(3-Acetamidophenyl)methyl]piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide	IC50	551.0 [1]
	7-Fluoro-4-oxo-N-[1-[(3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperidin-4-yl]chromene-2-carboxamide	IC50	233.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 50 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Melanin-concentrating hormone receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/melanin-concentrating-hormone-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Melanin-concentrating hormone receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/melanin-concentrating-hormone-receptor-inhibitors-ic50-ki.
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