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Metabotropic glutamate receptor 4 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Glutamic acidKi1400.0 [1], 1600.0 [2], 2400.0 [3], 3235.94 [4], 17000.0 [5]
(2S)-2-Amino-4-phosphonobutanoic acidKi160.0 [1], 470.0 [2], 910.0 [3]
CID 6324634IC50300000.0 [1]
CID 6324634Ki300000.0 [1]
Quisqualic acidKi112000.0 [1], 1000000.0 [2]
alpha-Methyl-4-carboxyphenylglycineIC501000000.0 [1]
alpha-Methyl-4-carboxyphenylglycineKi1000000.0 [1]
2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-AlanineIC5022000.0 [1]
2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-AlanineKi22000.0 [1]
(RS)-4-Carboxy-3-hydroxyphenylglycineIC501000000.0 [1]
(RS)-4-Carboxy-3-hydroxyphenylglycineKi1000000.0 [1]
(2R,1S,2R,3S)-2-(2-Carboxy-3-phenylcyclopropyl)glycineIC50300000.0 [1]
(2R,1S,2R,3S)-2-(2-Carboxy-3-phenylcyclopropyl)glycineKi280000.0 [1]
3-[(S)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acidIC50300000.0 [1]
3-[(S)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acidKi300000.0 [1]
(S)-4-CarboxyphenylglycineKi838000.0 [1], 1000000.0 [2]
2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acidIC50300000.0 [1]
2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acidKi300000.0 [1]
1-Amino-3-phosphono-3-cyclopentene-1-carboxylic acidIC50100000.0 [1]
(1S,2R,3R)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2R,3R)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
1-Amino-3-phosphono-2-cyclopentene-1-carboxylic acidIC50100000.0 [1]
(1R,2R,3S)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1R,2R,3S)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1S,2R,3S)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2R,3S)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1R,2S,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1R,2S,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1S,2S,3S)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2S,3S)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1S,2S,3S)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2S,3S)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1R,2R,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1R,2R,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1S,2R,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2R,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1S,2S,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2S,3R)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1S,2R,3S)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1S,2R,3S)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1R,2R,3R)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1R,2R,3R)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1R,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1R,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
(1R,2R,3S)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidIC50300000.0 [1]
(1R,2R,3S)-2-[(R)-Amino(carboxy)methyl]-3-phenylcyclopropane-1-carboxylic acidKi280000.0 [1]
Ibotenic acidKi1000000.0 [1]
2-Methyl-6-(phenylethynyl)pyridineKi100000.0 [1]
(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acidKi98000.0 [1]
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acidKi21000.0 [1]
EglumetadKi100000.0 [1]
AidaKi1000000.0 [1]
L-Homocysteic acidKi53000.0 [1]
(S)-4-((1-Carboxyethyl)amino)benzoic acidIC501000000.0 [1]
(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycineKi50000.0 [1]
(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acidKi300000.0 [1]
CPCCOEtKi100000.0 [1]
4-CarboxyphenylglycineIC501000000.0 [1]
2-Methyl-6-(2-phenylethenyl)pyridineKi26000.0 [1]
6-Methyl-2-(phenylazo)-3-pyridinolKi100000.0 [1]
L-2-Aminoadipic acidKi3000000.0 [1]
Benzonitrile, 3-fluoro-5-(2-(2-(fluoromethyl)-4-thiazolyl)ethynyl)-Ki10000.0 [1]
(S)-3,5-DihydroxyphenylglycineKi1000000.0 [1]
(2S)-2-Amino-4-[hydroxy-[hydroxy-(4-hydroxy-3-methoxy-5-nitrophenyl)methyl]phosphoryl]butanoic acidIC508600.0 [1]
N-(4-Chloro-3-methoxyphenyl)pyridine-2-carboxamideIC505.13 [1]
(RS)-PpgKi5200.0 [1]
13-(Dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-oneIC5010000.0 [1]
(S)-2-Amino-5-phosphonopentanoic acidKi1000000.0 [1]
6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-5H-1,3-benzoxazol-4-oneIC5010000.0 [1]
CID 10058694Ki100000.0 [1]
4-Methylene-L-glutamic acidKi1000000.0 [1]
(S)-2-Amino-4-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-butyric acidKi1000000.0 [1]
(2S,4S)-4-Methylglutamic acidKi470000.0 [1]
(S)-HiboKi1000000.0 [1]
4-[(S)-Amino(carboxy)methyl]cubane-1-carboxylic acidKi1000000.0 [1]
(2S,3S,4S)-2-Methyl-2-(carboxycyclopropyl)glycineKi1000000.0 [1]
(1r,2s,4r,5r,6r)-2-Amino-4-(1h-1,2,4-Triazol-3-Ylsulfanyl)bicyclo[3.1.0]hexane-2,6-Dicarboxylic AcidIC5012500.0 [1]
(S)-2-Amino-3-(4-butyl-3-hydroxy-isoxazol-5-yl)-propionic acidKi1000000.0 [1]
1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichlorophenyl)ethenyl]-1,2,4-triazoleKi100000.0 [1]
(1S,2S)-4-Aminocyclopentane-1,2,4-tricarboxylic acidKi8800.0 [1]
1-Adamantyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanoneIC5030000.0 [1]
N-(3-(Difluoromethoxy)phenyl)picolinamideIC504.57 [1]
N-Methyl-5-(phenylethynyl)pyrimidin-2-amineIC5010000.0 [1]
3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonitrileKi10000.0 [1]
CID 5311344Ki50000.0 [1]
2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acidKi1000000.0 [1]
(1S,3R)-1-Amino-3-(carboxymethyl)cyclopentane-1-carboxylic AcidKi1000000.0 [1]
(2R,4R)-1,4-Diamino-pyrrolidine-2,4-dicarboxylic acidKi1000000.0 [1]
3,4-Dimethoxy-N-[2-(1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]benzamideIC5010000.0 [1]
1-Benzyl-APDCIC50300000.0 [1]
N-[3-(Methylsulfanyl)phenyl]pyridine-2-carboxamideIC504.9 [1]
N-(4-Fluoro-3-methoxyphenyl)picolinamideIC5031.62 [1]
2-Amino-bicyclo[3.2.0]heptane-2,7-dicarboxylic acidKi1000000.0 [1]
N-[3-Chloro-4-(4-methyl-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamideIC5011.0 [1]
3-[(R)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-phenylethyl)cyclopropane-1-carboxylic acidIC5011410.0 [1]
N-(4-Chloro-3-methoxyphenyl)-6-fluoropyridine-2-carboxamideIC507.41 [1]
N-[3-(Difluoromethoxy)phenyl]-6-fluoropyridine-2-carboxamideIC506.61 [1]
Amino(3-hydroxyphenyl)acetic acidKi1000000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Metabotropic glutamate receptor 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Metabotropic glutamate receptor 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-4-inhibitors-ic50-ki.
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