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Metabotropic glutamate receptor 8 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
CID 6324634IC50300000.0 [1]
CID 6324634Ki300000.0 [1]
Glutamic acidIC505.7 [1]
Glutamic acidKi9500.0 [1]
2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-AlanineIC50170.0 [1]
2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-AlanineKi170.0 [1]
2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acidIC50300000.0 [1]
2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acidKi300000.0 [1]
2-Methyl-6-(phenylethynyl)pyridineKi100000.0 [1]
(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acidKi45000.0 [1]
2-Amino-4-phosphonobutyric acidIC505.1 [1]
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acidKi1700.0 [1]
EglumetadKi12000.0 [1]
(S)-4-((1-Carboxyethyl)amino)benzoic acidIC501000000.0 [1]
(2S)-2-Amino-4-phosphonobutanoic acidKi61.0 [1]
(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycineKi3400.0 [1]
(2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acidKi100000.0 [1]
CPCCOEtKi100000.0 [1]
2-Methyl-6-(2-phenylethenyl)pyridineKi100000.0 [1]
6-Methyl-2-(phenylazo)-3-pyridinolKi100000.0 [1]
Benzonitrile, 3-fluoro-5-(2-(2-(fluoromethyl)-4-thiazolyl)ethynyl)-Ki10000.0 [1]
(S)-3,5-DihydroxyphenylglycineKi1000000.0 [1]
(RS)-PpgKi210.0 [1]
4-Fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)thiazol-2-yl)-N-methylbenzamideIC5010000.0 [1]
CID 10058694Ki7300.0 [1]
DfmtiIC5010000.0 [1]
(1r,2s,4r,5r,6r)-2-Amino-4-(1h-1,2,4-Triazol-3-Ylsulfanyl)bicyclo[3.1.0]hexane-2,6-Dicarboxylic AcidIC5012500.0 [1]
1-Adamantyl-[4-(1,3-thiazol-2-yl)piperazin-1-yl]methanoneIC5030000.0 [1]
N-Methyl-5-(phenylethynyl)pyrimidin-2-amineIC5010000.0 [1]
3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonitrileKi10000.0 [1]
1-Benzyl-APDCIC50300000.0 [1]
(2R,4R)-4-Amino-1-naphthalen-1-ylmethyl-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-phenylethyl)cyclopropane-1-carboxylic acidIC50990.0 [1]
N-[4-Chloro-3-[dideuterio(fluoro)methoxy]phenyl]pyridine-2-carboxamideIC5030000.0 [1]
2-(m-Tolylethynyl)pyrimidineIC5010000.0 [1]
(2R,4R)-4-Amino-1-(3-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-[(2,6-dichlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-methylpyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-ethylpyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine-2,4-dicarboxylic acidIC50300000.0 [1]
(2R,3R,6S)-2-Amino-3-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acidKi15000.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-butylcyclopropane-1-carboxylic acidIC50490.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-methylcyclopropane-1-carboxylic acidIC501230.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-propylcyclopropane-1-carboxylic acidIC502250.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-nonylcyclopropane-1-carboxylic acidIC505180.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-hexylcyclopropane-1-carboxylic acidIC50750.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-pentylcyclopropane-1-carboxylic acidIC50340.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-(2-methylpropyl)cyclopropane-1-carboxylic acidIC50380.0 [1]
(1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-ethylcyclopropane-1-carboxylic acidIC502520.0 [1]
Cyclobutyl(2-azaspiro[5.5]undecan-2-yl)methanoneIC5030000.0 [1]
(1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-dichlorophenyl)methoxy]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acidIC501900.0 [1]
(1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acidIC5012500.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Metabotropic glutamate receptor 8 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-8-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Metabotropic glutamate receptor 8 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/metabotropic-glutamate-receptor-8-inhibitors-ic50-ki.
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