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Mitogen-activated protein kinase kinase kinase 8 Inhibitors (IC50, Ki)
Structure | Compound Name | Standard Type | Standard Values (in nM) |
|---|---|---|---|
 | N-(2-Morpholin-4-ylethyl)-6-(8-phenylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine | IC50 | 16.0 [1], 270.0 [2], 280.0 [3], 2500.0 [4] |
 | N-[(2R)-1-Morpholin-4-ylpropan-2-yl]-6-(8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)quinolin-2-amine | IC50 | 4.0 [1], 30.0 [2], 80.0 [3] |
 | 1-Quinolin-6-yl-8-thiophen-3-ylimidazo[4,5-c][1,7]naphthyridine | IC50 | 20.0 [1], 440.0 [2], 540.0 [3], 1780.0 [4] |
 | N-(1-Morpholin-4-ylpropan-2-yl)-6-(8-pyridin-4-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine | IC50 | 9.0 [1], 70.0 [2], 80.0 [3], 600.0 [4] |
 | N-(1-Morpholin-4-ylpropan-2-yl)-6-(8-thiophen-2-ylimidazo[4,5-c][1,7]naphthyridin-1-yl)-1,3-benzothiazol-2-amine | IC50 | 22.0 [1], 280.0 [2], 290.0 [3], 10000.0 [4] |
References
This online resource may be cited as follows
MLA | "Quest Database™ Mitogen-activated protein kinase kinase kinase 8 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 13 Dec. 2025, https://www.aatbio.com/data-sets/mitogen-activated-protein-kinase-kinase-kinase-8-inhibitors-ic50-ki. | |
APA | AAT Bioquest, Inc. (2025, December 13). Quest Database™ Mitogen-activated protein kinase kinase kinase 8 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/mitogen-activated-protein-kinase-kinase-kinase-8-inhibitors-ic50-ki. | |
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