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Monoglyceride lipase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
4-Nitrophenyl 4-[bis(2H-1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylateIC5010.0 [1]
Benzyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamateIC5092.0 [1]
Methoxy arachidonyl fluorophosphonateIC5026.3 [1]
[4-(13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-(1,2,4-triazol-1-yl)methanoneIC50208.93 [1]
1-[[4-(4-Chlorobenzoyl)piperidine-1-yl]carbonyl]-4-methoxybenzeneIC5011700.0 [1], 12000.0 [2], 12200.0 [3], 12700.0 [4]
1-[[4-(4-Chlorobenzoyl)piperidine-1-yl]carbonyl]-4-methoxybenzeneKi8600.0 [1]
N-ArachidonylmaleimideIC50140.0 [1], 1120.0 [2], 2800.0 [3]
5-Methoxy-3-(4-phenoxyphenyl)-1,3,4-oxadiazol-2-oneIC5031.0 [1], 78.0 [2], 310.0 [3], 1700.0 [4]
(4-Benzylpiperidin-1-yl)-[5-(4-hydroxyphenyl)-1-[(3-methylphenyl)methyl]pyrazol-3-yl]methanoneIC50390.0 [1], 500.0 [2], 510.0 [3]
(4-Benzylpiperidin-1-yl)-[5-(4-hydroxyphenyl)-1-[(3-methylphenyl)methyl]pyrazol-3-yl]methanoneKi412.0 [1]
5-Ethoxy-3-(3-phenoxyphenyl)-1,3,4-oxadiazol-2-oneIC5091.2 [1], 93.33 [2], 154.88 [3], 676.08 [4]
Cyclohexyl biphenyl-3-ylcarbamateIC509100.0 [1], 10000.0 [2]
N,N-Dimethyl-5-[(4-phenylphenyl)methyl]-1-tetrazolecarboxamideIC5054.4 [1], 54.95 [2], 290.0 [3]
CID 76313567IC500.36 [1], 0.4 [2]
Bis(4-methyl-1-piperazinylthiocarbonyl) disulfideIC50109.65 [1], 302.0 [2], 8317.64 [3]
4-(3-Fluoro-4-hydroxyphenyl)-2-[(E)-N-hydroxy-C-tridecylcarbonimidoyl]phenolIC50680.0 [1], 700.0 [2]
DisulfiramIC50360.0 [1], 1258.93 [2]
Aacocf3IC506310.0 [1], 6456.54 [2]
1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(3-phenoxybenzyl)piperazine-1-carboxylateIC503.7 [1], 74.0 [2]
1,2-Benzisothiazol-3(2H)-one, 2-octyl-IC50660.0 [1], 1660.0 [2]
[(1R)-1-[(3S)-2-Oxo-1-pent-4-enoylazetidin-3-yl]ethyl] 4-phenylbutanoateIC504060.0 [1]
Benzotriazol-1-yl-(4-benzylpiperazin-1-yl)methanoneIC508.0 [1]
Benzotriazol-1-yl-[4-[(4-nitrophenyl)methyl]piperazin-1-yl]methanoneIC5012.0 [1]
Benzotriazol-1-yl-[4-[(4-bromophenyl)methyl]piperazin-1-yl]methanoneIC509.0 [1]
Benzotriazol-1-yl-[4-(naphthalen-2-ylmethyl)piperazin-1-yl]methanoneIC509.0 [1]
Benzotriazol-1-yl-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methanoneIC5033.0 [1]
5-Methoxy-3-[[4-(2-methylpropyl)phenyl]methyl]-1,3,4-oxadiazol-2-oneIC501300.0 [1], 1348.96 [2]
5-Methoxy-3-[(4-phenylphenyl)methyl]-1,3,4-oxadiazol-2-oneIC501600.0 [1], 1621.81 [2]
5-Methoxy-3-[(4-phenoxyphenyl)methyl]-1,3,4-oxadiazol-2-oneIC50398.11 [1], 400.0 [2]
3-Isothiazolidinone, 2-octyl-IC50140.0 [1], 1090.0 [2]
(3S,4R)-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1,2,4-triazole-1-carbonyl)piperidin-4-yl]azetidin-2-oneIC5031.2 [1], 728.5 [2]
(3R,4S)-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1,2,4-triazole-1-carbonyl)piperidin-4-yl]azetidin-2-oneIC507.4 [1], 104.4 [2]
1-(1-Phenyl-3,4-dihydro-2H-quinolin-4-yl)pyrrolidin-2-oneIC502200.0 [1], 3800.0 [2]
[(2R)-Oxiran-2-yl]methyl 2-(4-benzylphenyl)acetateIC502400.0 [1]
[(2R)-Oxiran-2-yl]methyl 2-(4-benzylphenyl)acetateKi40000.0 [1]
(4-Benzhydrylpiperazin-1-yl)-(benzotriazol-1-yl)methanoneIC500.54 [1]
(4-Benzhydrylpiperazin-1-yl)-(benzotriazol-1-yl)methanoneKi75.7 [1]
N-EthylmaleimideIC5016600.0 [1]
ThiramIC50977.24 [1]
N-PhenylmaleimideIC5015900.0 [1]
Diphenyl disulfideIC501600.0 [1]
N,N'-4-PhenylenedimaleimideIC502220.0 [1]
1,6-BismaleimidohexaneIC501700.0 [1]
N-MethylmaleimideIC5024500.0 [1]
Methyl diethyldithiocarbamateIC501000000.0 [1]
Tetramethylthiuram monosulfideIC5012302.69 [1]
Psncbam 1IC50100000.0 [1]
Benzo[B]thiophene-2-boronic acidIC5032000.0 [1]
N-BenzylmaleimideIC505140.0 [1]
4,4'-DithiodimorpholineIC5011220.18 [1]
Dipentamethylenethiuram disulfideIC50316.23 [1]
CID 71656212IC505.9 [1]
Dimorpholinethiuram disulfideIC50218.78 [1]
4-Biphenylboronic acidIC5019000.0 [1]
4-[2-(4-Methylphenyl)ethanethioyl]morpholineIC5023988.33 [1]
1-(4-Methylphenyl)-1H-pyrrole-2,5-dioneIC5014100.0 [1]
Maleimide, N-phenethyl-IC507610.0 [1]
5-([1,1'-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamideIC506.0 [1]
1-(4-Hydroxyphenyl)-1H-pyrrole-2,5-dioneIC5012900.0 [1]
1-(2-Methoxyphenyl)-1H-pyrrole-2,5-dioneIC506920.0 [1]
1-[4-[4-(4-Fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl]-2-phenylethanoneIC50500000.0 [1]
N-(4-Bromophenyl)maleimideIC504370.0 [1]
1-[4-(4-Fluorophenyl)piperazin-1-yl]-2-[5-(4-methoxyphenyl)tetrazol-2-yl]ethanoneIC50500000.0 [1]
Orlistat derivative, 17cIC50890.0 [1]
5-(4-Hydroxyphenyl)Pentanesulfonyl FluorideIC50383.1 [1]
4-Nitrophenyl 4-(bis(4-fluorophenyl)methyl)piperazine-1-carboxylateIC50347.0 [1]
4-(Trifluoromethyl)phenylboronic acidIC5020000.0 [1]
2-(3,4-Dimethoxy-phenyl)-1-morpholin-4-yl-ethanethioneIC501000000.0 [1]
1-(Biphenyl-3-yl)-1H-pyrrole-2,5-dioneIC502340.0 [1]
1-(4-Chlorophenyl)-1H-pyrrole-2,5-dioneIC507240.0 [1]
MALEIMIDE, N-o-TOLYL-IC502690.0 [1]
Biphenyl-4-yl(morpholin-4-yl)methanethioneIC5019498.45 [1]
2-(4-Chlorophenyl)-1-morpholin-4-yl-ethanthioneIC5014791.08 [1]
1-(4-Methoxyphenyl)-1H-pyrrole-2,5-dioneIC505750.0 [1]
1-(3-Methylphenyl)-1h-pyrrole-2,5-dioneIC502750.0 [1]
1-(3-Chlorophenyl)-1H-pyrrole-2,5-dioneIC502820.0 [1]
Benzofuran-2-boronic acidIC50100000.0 [1]
1-(3-Methoxyphenyl)-1H-pyrrole-2,5-dioneIC506600.0 [1]
LutiramIC50912.01 [1]
(4-Chlorophenyl)(morpholino)methanethioneIC5077624.71 [1]
(4-(Dimethylamino)phenyl)(morpholino)methanethioneIC501000000.0 [1]
Morpholine, 4-(phenylthioacetyl)-IC501000000.0 [1]
Methyl 4-(4-morpholinylcarbonothioyl)benzoateIC5030902.95 [1]
1-(4-Phenylbutyl)-1H-pyrrole-2,5-dioneIC502140.0 [1]
N,N'-DithiobisdiethylamineIC507943.28 [1]
5-Methoxy-3-(3-phenoxyphenyl)-1,3,4-oxadiazol-2-oneIC50110.0 [1]
2-(Biphenyl-4-yl)-1-(morpholin-4-yl)ethanethioneIC505754.4 [1]
N-(4-Chlorobenzoyl)morpholineIC501000000.0 [1]
3-(Trifluoromethyl)phenylboronic acidIC5038000.0 [1]
4-(1,2,3-Thiadiazol-4-yl)phenyl butylcarbamateIC5043000.0 [1]
1-(4-Isopropylphenyl)-1H-pyrrole-2,5-dioneIC502880.0 [1]
1-(2-Fluorophenyl)-1H-pyrrole-2,5-dioneIC504470.0 [1]
[3-[(S)-(4-Chlorophenyl)-(2-chloropyridin-3-yl)methoxy]azetidin-1-yl]-piperidin-1-ylmethanoneIC5022300.0 [1]
4-Nonylphenylboronic acidIC507900.0 [1]
N-(2-Phenylethyl)benzenecarbothioamideIC501000000.0 [1]
1H-Pyrrole-2,5-dione, 1,1'-(methylenedi-4,1-phenylene)bis-IC502240.0 [1]
N-(4-Iodophenyl)maleimideIC504340.0 [1]
1-(3-Fluorophenyl)-1H-pyrrole-2,5-dioneIC502390.0 [1]
(4-Benzhydrylpiperazin-1-yl)-(1,2,4-triazol-1-yl)methanoneIC501.3 [1]
Dimethylcarbamothioyl morpholine-4-carbodithioateIC506456.54 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Monoglyceride lipase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/monoglyceride-lipase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Monoglyceride lipase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/monoglyceride-lipase-inhibitors-ic50-ki.
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