NACHT, LRR and PYD domains-containing protein 3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-4-(2-hydroxypropan-2-yl)furan-2-sulfonamide	IC50	5.0 [1], 8.0 [2]
	Glyburide	IC50	12000.0 [1]
	Isoliquiritigenin	IC50	1540.0 [1]
	Levoglucosenone	IC50	6600.0 [1]
	(1S,2S,4R,7E,11R)-4,8-Dimethyl-12-methylidene-3-oxatricyclo[9.3.0.02,4]tetradec-7-en-13-one	IC50	2590.0 [1]
	1-(1-Hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea	IC50	1971.0 [1]
	1-(3-Hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea	IC50	232.0 [1]
	Chembl4127699	IC50	42000.0 [1]
	1-[(1S)-1-Hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl]-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea	IC50	6352.0 [1]
	1-(2-Hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea	IC50	1828.0 [1]
	1-[(1R)-1-Hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl]-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea	IC50	1238.0 [1]
	1-[4-(1,1,1,3,3,3-Hexadeuterio-2-hydroxypropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea	IC50	5.0 [1]
	[(2S)-5-Oxo-2H-pyran-2-yl]methyl acetate	IC50	4300.0 [1]
	[(2S)-4-Fluoro-5-oxo-2H-pyran-2-yl]methyl acetate	IC50	3700.0 [1]
	(1R,5S)-3-Fluoro-6,8-dioxabicyclo[3.2.1]oct-2-en-4-one	IC50	4800.0 [1]
	[(2S)-5-Oxo-2H-pyran-2-yl]methyl octanoate	IC50	5100.0 [1]
	(5S,6R)-5-Hydroxy-6-(hydroxymethyl)oxan-3-one	IC50	2300000.0 [1]
	[(2S)-5-Oxo-2H-pyran-2-yl]methyl butanoate	IC50	3600.0 [1]
	[(1R,5S)-2-Acetyl-3-fluoro-6,8-dioxabicyclo[3.2.1]oct-3-en-4-yl] acetate	IC50	3700.0 [1]
	1-[4-(2-Hydroxypropan-2-yl)furan-2-yl]sulfonyl-3-(3,3,5,5-tetradeuterio-1,2,6,7-tetrahydro-s-indacen-4-yl)urea	IC50	6.0 [1]
	1-(7,7-Dideuterio-2,3,5,6-tetrahydro-1H-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea	IC50	6.0 [1]
	(NE)-N-[1-(6-methoxy-1,3-benzoxazol-2-yl)-2-(4-methoxyphenyl)ethylidene]hydroxylamine	IC50	1220.0 [1]
	(NE)-N-[1-(6-methyl-1,3-benzoxazol-2-yl)-2-phenylethylidene]hydroxylamine	IC50	15880.0 [1]
	(NE)-N-[1-(6-chloro-1,3-benzoxazol-2-yl)-2-phenylethylidene]hydroxylamine	IC50	21950.0 [1]
	1-[4-(2-Hydroxypropan-2-yl)furan-2-yl]sulfonyl-3-(1,1,7,7-tetradeuterio-2,3,5,6-tetrahydro-s-indacen-4-yl)urea	IC50	7.0 [1]
	(NE)-N-[1-(6-chloro-1,3-benzoxazol-2-yl)-2-(4-methoxyphenyl)ethylidene]hydroxylamine	IC50	5720.0 [1]
	[(E)-1-(1,3-Benzoxazol-2-yl)ethylideneamino] 2-methoxybenzoate	IC50	39470.0 [1]
	1-[4-Chloro-2,6-di(propan-2-yl)phenyl]-3-[3-(1-hydroxyethyl)phenyl]sulfonylurea	IC50	210.0 [1]
	1-[4-Chloro-2,6-di(propan-2-yl)phenyl]-3-[3-(2-hydroxypropan-2-yl)phenyl]sulfonylurea	IC50	260.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 29 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ NACHT, LRR and PYD domains-containing protein 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/nacht-lrr-and-pyd-domains-containing-protein-3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ NACHT, LRR and PYD domains-containing protein 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nacht-lrr-and-pyd-domains-containing-protein-3-inhibitors-ic50-ki.
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