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NAD kinase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Benzamide adenine nucleotideIC5090000.0 [1]
Benzamide adenine nucleotideKi90000.0 [1]
(2R,3R,4S,5S)-2-(6-Aminopurin-9-yl)-5-[[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldisulfanyl]methyl]oxolane-3,4-diolIC5087000.0 [1]
8-[(2-{[2-(3-Bromophenyl)ethyl]amino}-2-Oxoethyl)sulfanyl]adenosineKi335000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3-bromophenyl)ethyl]acetamideKi330000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(5-chloro-1H-indol-3-yl)ethyl]acetamideKi775000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3-chlorophenyl)ethyl]acetamideKi200000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(4-bromophenyl)ethyl]acetamideKi250000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(1H-indol-3-yl)ethyl]acetamideKi140000.0 [1]
3-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3-bromophenyl)ethyl]propanamideKi80000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3,4-dichlorophenyl)ethyl]acetamideKi180000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(4-bromophenyl)ethyl]acetamideKi80000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3,4-dichlorophenyl)ethyl]acetamideKi425000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-[4-(trifluoromethyl)phenyl]ethyl]acetamideKi230000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[(3-bromophenyl)methyl]acetamideKi55000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamideKi160000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3,4-dichlorophenyl)ethyl]acetamideKi140000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3-chlorophenyl)ethyl]acetamideKi20000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(4-bromophenyl)ethyl]acetamideKi130000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(1H-benzimidazol-2-yl)ethyl]acetamideKi525000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-(2-phenylethyl)acetamideKi350000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-(2-naphthalen-2-ylethyl)acetamideKi140000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3,4-dichlorophenyl)ethyl]acetamideKi130000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-[3-(trifluoromethyl)phenyl]ethyl]acetamideKi300000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(4-chlorophenyl)ethyl]acetamideKi210000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(1-methylindol-3-yl)ethyl]acetamideKi350000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-prop-2-ynylacetamideKi140000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-[(dimethylsulfamoylamino)methyl]-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(3,4-dichlorophenyl)ethyl]acetamideKi160000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[2-(5-chloro-1H-indol-3-yl)ethyl]acetamideKi65000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-[(2-chloropyridin-4-yl)methyl]acetamideKi220000.0 [1]
2-[6-Amino-9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]purin-8-yl]sulfanyl-N-(3-phenylpropyl)acetamideKi150000.0 [1]
(2S,3S,4R,5R)-2-[[[(2S,3S,4R,5R)-5-(6-Amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldisulfanyl]methyl]-5-(6-aminopurin-9-yl)oxolane-3,4-diolIC506000.0 [1]
(2R,3R,4S,5S)-2-(6-Amino-8-bromopurin-9-yl)-5-[[[(2S,3S,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldisulfanyl]methyl]oxolane-3,4-diolIC506000.0 [1]
2-[(2R,3R,4S,5S)-5-[[[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldisulfanyl]methyl]-3,4-dihydroxyoxolan-2-yl]-1,3-thiazole-4-carboxamideIC50110000.0 [1]
(2R,3R,4S,5S)-2-(6-Amino-8-phenylpurin-9-yl)-5-[[[(2S,3S,4R,5R)-5-(6-amino-8-phenylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyldisulfanyl]methyl]oxolane-3,4-diolIC5045000.0 [1]
(2R,3R,4R,5S)-2-(6-Aminopurin-9-yl)-5-[[[(2S,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]methyldisulfanyl]methyl]-3-methyloxolane-3,4-diolIC50280000.0 [1]
Items per page: 1 - 10 of 36
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References

This online tool may be cited as follows

MLA

"Quest Database™ NAD kinase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 5 May. 2024, https://www.aatbio.com/data-sets/nad-kinase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 5). Quest Database™ NAD kinase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nad-kinase-inhibitors-ic50-ki.
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