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NADPH oxidase 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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(1R,8S,10S)-3,6-Dibromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC5060000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylpropyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC5032000.0 [1]
(1R,8S,10S)-9-[(3-Fluorophenyl)methyl]-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(quinolin-4-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-9-(1H-indol-3-ylmethyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-9-(1,3-Benzodioxol-5-ylmethyl)-3-bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
3-[[(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trien-9-yl]methyl]-5-methyl-1,2-oxazoleIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-9-[(3-fluorophenyl)methyl]-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-pentyl-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-9-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4-dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-(3,4-Dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-pentyl-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-9-(4-fluorophenyl)sulfonyl-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC5031000.0 [1]
(1R,8S,10S)-11,11-Dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
(1R,8S,10S)-3-(3,4-Dichlorophenyl)-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-trieneIC50100000.0 [1]
2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dioneKi165.0 [1]
3-Phenyl-1-pyridin-2-yl-1H-pyrazol-5-olKi1450.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(thiophen-2-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
(5Z)-3-Cyclohexyl-5-[(2,3-dihydroxyphenyl)methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi7390.0 [1]
(5Z)-5-[(2,4-Dihydroxyphenyl)methylidene]-1-methyl-3-phenyl-2-sulfanylideneimidazolidin-4-oneKi33800.0 [1]
(5Z)-5-[(2,3-Dihydroxyphenyl)methylidene]-1-methyl-3-phenyl-2-sulfanylideneimidazolidin-4-oneKi49700.0 [1]
(5Z)-5-[(2,4-Dihydroxyphenyl)methylidene]-1-methyl-3-(4-methylphenyl)-2-sulfanylideneimidazolidin-4-oneKi27100.0 [1]
(5Z)-5-[[4-(Dimethylamino)phenyl]methylidene]-1-methyl-3-(4-methylphenyl)-2-sulfanylideneimidazolidin-4-oneKi1020.0 [1]
(5Z)-3-(3-Chlorophenyl)-5-[(2,4-dihydroxyphenyl)methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi34500.0 [1]
(5Z)-3-Cyclohexyl-5-[(2,4-dihydroxyphenyl)methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi26000.0 [1]
(5Z)-5-[(2,3-Dihydroxyphenyl)methylidene]-3-(4-ethylphenyl)-1-methyl-2-sulfanylideneimidazolidin-4-oneKi27900.0 [1]
(5Z)-5-[(2,3-Dihydroxyphenyl)methylidene]-1-methyl-3-(4-methylphenyl)-2-sulfanylideneimidazolidin-4-oneKi50300.0 [1]
(5Z)-5-[(2,4-Dihydroxyphenyl)methylidene]-3-(4-ethylphenyl)-1-methyl-2-sulfanylideneimidazolidin-4-oneKi8400.0 [1]
(5Z)-5-[[4-(Dimethylamino)phenyl]methylidene]-3-(4-ethylphenyl)-1-methyl-2-sulfanylideneimidazolidin-4-oneKi4390.0 [1]
(5Z)-3-(3-Chlorophenyl)-5-[(2,3-dihydroxyphenyl)methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi7650.0 [1]
(5Z)-3-(3-Chlorophenyl)-5-[[4-(dimethylamino)phenyl]methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi350.0 [1]
(5Z)-3-(2,3-Dihydro-1H-inden-5-yl)-5-[(2,4-dihydroxyphenyl)methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi6580.0 [1]
(5Z)-3-(2,3-Dihydro-1H-inden-5-yl)-5-[(2,3-dihydroxyphenyl)methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi6630.0 [1]
(5Z)-5-[[4-(Dimethylamino)phenyl]methylidene]-1-methyl-3-phenyl-2-sulfanylideneimidazolidin-4-oneKi1950.0 [1]
(5Z)-3-(2,3-Dihydro-1H-inden-5-yl)-5-[[4-(dimethylamino)phenyl]methylidene]-1-methyl-2-sulfanylideneimidazolidin-4-oneKi8040.0 [1]
Tert-butyl 4-(2-chlorophenyl)-3,8-dioxo-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-13-carboxylateKi148.0 [1]
4-(2-Chlorophenyl)-13-[(4-chlorophenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi95.0 [1]
4-(2-Chlorophenyl)-13-(pyridin-3-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi208.0 [1]
12-Benzyl-4-(2-chlorophenyl)-4,5,9,12-tetrazatricyclo[7.4.0.02,6]trideca-1,6-diene-3,8-dione;hydrochlorideKi398.0 [1]
4-(2-Chlorophenyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi119.0 [1]
4-(2-Chlorophenyl)-13-[(3-chlorophenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi104.0 [1]
4-(2-Chlorophenyl)-12-oxa-4,5,9-triazatricyclo[7.4.0.02,6]trideca-1,6-diene-3,8-dioneKi173.0 [1]
4-(2-Methoxyphenyl)-13-[(3-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi212.0 [1]
13-Benzyl-4-(2-chlorophenyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi101.0 [1]
4-(2-Chlorophenyl)-13-[(2-chlorophenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi87.0 [1]
4-(2-Chlorophenyl)-13-[(4-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi184.0 [1]
13-Benzyl-4-(2-methoxyphenyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi218.0 [1]
4-(2-Chlorophenyl)-13-[(2-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi133.0 [1]
4-(2-Chlorophenyl)-13-[(3-methoxyphenyl)methyl]-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi113.0 [1]
4-(2-Chlorophenyl)-13-(furan-3-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi200.0 [1]
4-(2-Methoxyphenyl)-13-(pyridin-2-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dione;hydrochlorideKi217.0 [1]
(5Z)-3-Cyclohexyl-5-[4-(dimethylamino)benzylidene]-1-methyl-2-thioxoimidazolidin-4-oneKi12300.0 [1]
(1R,8S,10S)-3-Bromo-11,11-dimethyl-10-(2-methylprop-2-enyl)-9-(thiophen-3-ylmethyl)-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-trieneIC50100000.0 [1]
4-(2-Chlorophenyl)-13-(pyridin-2-ylmethyl)-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-3,8-dioneKi113.0 [1]
Items per page: 1 - 10 of 54
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References

This online tool may be cited as follows

MLA

"Quest Database™ NADPH oxidase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 2 May. 2024, https://www.aatbio.com/data-sets/nadph-oxidase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 2). Quest Database™ NADPH oxidase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nadph-oxidase-1-inhibitors-ic50-ki.
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