Neutral cholesterol ester hydrolase 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 10427006	IC50	100000.0 [1]
	1-(Oxazol-2-yl)-7-phenylheptan-1-one	IC50	19000.0 [1], 20000.0 [2]
	2-(7-Phenylheptanoyl)oxazole-5-carbonitrile	IC50	100000.0 [1]
	2-(7-Phenylheptanoyl)oxazole-5-carboxylic acid	IC50	100000.0 [1]
	6-[2-(7-Phenylheptanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid	IC50	100000.0 [1]
	(2-Fluorophenyl) N-[2-[[(1R,2S)-2-(butoxymethyl)cyclohexyl]methoxy]ethyl]carbamate	IC50	100.0 [1], 150.0 [2], 5400.0 [3]
	7-Phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	Methyl 2-(7-phenylheptanoyl)oxazole-5-carboxylate	IC50	100000.0 [1]
	(1-Bromonaphthalen-2-yl) N-butylcarbamate	IC50	2200.0 [1], 37000.0 [2]
	(1-Bromonaphthalen-2-yl) N-benzylcarbamate	IC50	710.0 [1], 27000.0 [2]
	(1-Bromonaphthalen-2-yl) azetidine-1-carboxylate	IC50	330.0 [1], 2000.0 [2]
	(1-Bromonaphthalen-2-yl) N-propan-2-ylcarbamate	IC50	1500.0 [1], 28000.0 [2]
	1-Bromo-2-naphthyl piperidinecarboxylate	IC50	1100.0 [1], 42000.0 [2]
	1-Bromonaphthalen-2-yl N,N-dimethylcarbamate	IC50	1200.0 [1], 1700.0 [2]
	Orlistat	IC50	100000.0 [1]
	1,6-Bis(cyclohexyloximinocarbonyl)hexane	IC50	10000.0 [1]
	7-Phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-[5-(Pyridin-2-Yl)-1,3,4-Oxadiazol-2-Yl]heptan-1-One	IC50	90000.0 [1]
	1-(5-(Furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	1-Chloro-2-naphthyl dimethylcarbamate	IC50	1100.0 [1]
	7-Phenyl-1-(5-phenyl-1,3,4-oxadiazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(5-(thiophen-2-yl)oxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	3-(4-Phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]propan-1-one	IC50	100000.0 [1]
	1-[5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl]-7-phenylheptan-1-one	IC50	100000.0 [1]
	1-(5-Bromooxazol-2-yl)-7-phenylheptan-1-one	IC50	13000.0 [1]
	Methyl 6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinate	IC50	240000.0 [1]
	3-(4-(Phenoxymethyl)phenyl)-1-(5-(pyridin-2-yl)oxazol-2-yl)propan-1-one	IC50	100000.0 [1]
	2-(3-(Biphenyl-4-yl)propanoyl)oxazole-5-carbonitrile	IC50	64000.0 [1]
	7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(2H-tetrazol-5-yl)-heptan-1-one	IC50	60000.0 [1]
	2-(7-Phenylheptanoyl)oxazole-5-carboxamide	IC50	100000.0 [1]
	3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzamide	IC50	100000.0 [1]
	1-(5-(4-Methoxypyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	6-(2-(7-Phenylheptanoyl)oxazol-5-yl)nicotinic acid	IC50	100000.0 [1]
	3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzoic acid	IC50	100000.0 [1]
	3-(2-(7-Phenylheptanoyl)oxazol-5-yl)benzenesulfonamide	IC50	100000.0 [1]
	1-(5-(4-Methylpyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	1-Oxo-1-[5-(2-pyridyl)oxazol-2-yl]-3-(4-phenoxyphenyl)propane	IC50	100000.0 [1]
	6-[2-(3-Biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid	IC50	100000.0 [1]
	7-Phenyl-1-[5-[6-(2H-tetrazol-5-yl)pyridin-2-yl]-1,3-oxazol-2-yl]heptan-1-one	IC50	100000.0 [1]
	Methyl 3-(7-Phenylheptanoyl)-1,2,4-oxadiazole-5-carboxylate	IC50	100000.0 [1]
	7-Phenyl-1-(5-(pyridin-2-yl)-thiazol-2-yl)-heptan-1-one	IC50	100000.0 [1]
	Methyl 5-(7-Phenylheptanoyl)-1,3,4-thiadiazole-2-carboxylate	IC50	100000.0 [1]
	1-(1,3,4-Oxadiazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	6-(5-(7-Phenylheptanoyl)-1,3,4-oxadiazol-2-yl)picolinic acid	IC50	100000.0 [1]
	1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one	IC50	25000.0 [1]
	7-Phenyl-1-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)heptan-1-one	IC50	30000.0 [1]
	Methyl 6-(5-(7-Phenylheptanoyl)-1,2,4-oxadiazol-3-yl)-picolinate	IC50	40000.0 [1]
	6-(5-(7-Phenylheptanoyl)-1,2,4-oxadiazol-3-yl)-picolinic Acid	IC50	100000.0 [1]
	7-Phenyl-1-(5-(pyridin-2-yl)-1,2,4-oxadiazol-3-yl)-heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(1,3,4-thiadiazol-2-yl)-heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)-heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(pyridazin-3-yl)-heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(6-(pyridin-2-yl)-pyridazin-3-yl)-heptan-1-one	IC50	100000.0 [1]
	2-(7-Phenylheptanoyl)oxazole-4-carbonitrile	IC50	30000.0 [1]
	7-Phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(4-(pyridin-4-yl)oxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	7-Phenyl-1-(4-(trifluoromethyl)oxazol-2-yl)heptan-1-one	IC50	10000.0 [1]
	1,6-Dibromonaphthalen-2-yl N,N-dimethylcarbamate	IC50	50.0 [1]
	2-(2-(7-Phenylheptanoyl)oxazol-5-yl)isonicotinonitrile	IC50	100000.0 [1]
	1-(5-(4-Nitropyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	1-(5-(4-Fluoropyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	Methyl 2-(2-(7-phenylheptanoyl)oxazol-5-yl)isonicotinate	IC50	100000.0 [1]
	6-(2-(7-Phenylheptanoyl)oxazol-5-yl)pyrimidine-2,4(1H,3H)-dione	IC50	100000.0 [1]
	7-Phenyl-1-(5-(4-(trifluoromethyl)pyridin-2-yl)oxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	1-(5-(4-Aminopyridin-2-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	5-(2-(7-Phenylheptanoyl)oxazol-5-yl)furan-2-carboxylic acid	IC50	100000.0 [1]
	7-Phenyl-1-(5-(piperidine-1-carbonyl)oxazol-2-yl)heptan-1-one	IC50	100000.0 [1]
	5-(2-(7-Phenylheptanoyl)oxazol-5-yl)pyrimidine-2,4(1H,3H)-dione	IC50	100000.0 [1]
	2-Naphthyl dimethylcarbamate	IC50	100000.0 [1]
	2-Bromophenyl Dimethylcarbamate	IC50	100000.0 [1]
	1-(5-(2,6-Dimethoxypyrimidin-4-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	1-(5-(2,4-Dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	3-(4-Phenylphenyl)-1-[5-[6-(2H-tetrazol-5-yl)pyridin-2-yl]-1,3-oxazol-2-yl]propan-1-one	IC50	100000.0 [1]
	1-(1,3-Oxazol-2-yl)-3-(4-phenoxyphenyl)propan-1-one	IC50	100000.0 [1]
	2-[3-(4-Phenoxyphenyl)propanoyl]-1,3-oxazole-5-carbonitrile	IC50	20000.0 [1]
	6-(2-(3-(4-Phenoxyphenyl)propanoyl)oxazol-5-yl)pyridine-2-carboxylic acid	IC50	100000.0 [1]
	1-(1,3-Oxazol-2-yl)-3-[4-(phenoxymethyl)phenyl]propan-1-one	IC50	100000.0 [1]
	2-[3-[4-(Phenoxymethyl)phenyl]propanoyl]-1,3-oxazole-5-carbonitrile	IC50	19000.0 [1]
	2-[3-(4-Phenylphenyl)propanoyl]-1,3-oxazole-5-carboxylic acid	IC50	100000.0 [1]
	1-(5-(6-(1H-Tetrazol-5-yl)pyridin-2-yl)oxazol-2-yl)-3-(4-(phenoxymethyl)phenyl)propan-1-one	IC50	100000.0 [1]
	2-[3-(4-Phenoxyphenyl)propanoyl]-1,3-oxazole-5-carboxylic acid	IC50	100000.0 [1]
	2-[3-[4-(Phenoxymethyl)phenyl]propanoyl]-1,3-oxazole-5-carboxylic acid	IC50	100000.0 [1]
	6-(2-(3-(4-(Phenoxymethyl)phenyl)propanoyl)oxazol-5-yl)pyridine-2-carboxylic acid	IC50	100000.0 [1]
	1-(1,3-Oxazol-2-yl)-3-(4-phenylphenyl)propan-1-one	IC50	100000.0 [1]
	6-(6-(7-Phenylheptanoyl)-pyridazin-3-yl)-picolinic Acid	IC50	100000.0 [1]
	Methyl 5-(7-Phenylheptanoyl)-1,3,4-oxadiazole-2-carboxylate	IC50	100000.0 [1]
	6-(6-(7-Phenylheptanoyl)pyridazin-3-yl)picolinonitrile	IC50	100000.0 [1]
	6-(3-(7-Phenylheptanoyl)-1,2,4-oxadiazol-5-yl)-picolinic Acid	IC50	100000.0 [1]
	6-(2-(7-Phenylheptanoyl)thiazol-5-yl)-picolinic Acid	IC50	100000.0 [1]
	Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2-yl)-picolinate	IC50	100000.0 [1]
	Methyl 6-(6-(7-Phenylheptanoyl)-pyridazin-3-yl)-picolinate	IC50	100000.0 [1]
	Methyl 6-(5-(7-Phenylheptanoyl)-1,3,4-oxadiazol-2-yl)-picolinate	IC50	100000.0 [1]
	1-(1,2,4-Oxadiazol-3-yl)-7-phenylheptan-1-one	IC50	100000.0 [1]
	Methyl 6-(3-(7-Phenylheptanoyl)-1,2,4-oxadiazol-5-yl)-picolinate	IC50	100000.0 [1]
	7-Phenyl-1-(thiazol-2-yl)-heptan-1-one	IC50	100000.0 [1]
	Methyl 6-(2-(7-Phenylheptanoyl)-thiazol-5-yl)-picolinate	IC50	100000.0 [1]
	6-(5-(7-Phenylheptanoyl)-1,3,4-thiadiazol-2-yl)-picolinic Acid	IC50	100000.0 [1]
	2-(7-Phenylheptanoyl)oxazole-4-carboxylic acid	IC50	100000.0 [1]
	(1-Bromo-6-propylnaphthalen-2-yl) N,N-dimethylcarbamate	IC50	130.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Neutral cholesterol ester hydrolase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/neutral-cholesterol-ester-hydrolase-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Neutral cholesterol ester hydrolase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/neutral-cholesterol-ester-hydrolase-1-inhibitors-ic50-ki.
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