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Nicotinamide N-methyltransferase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
3-[(2-Chloroacetyl)-(3-methylbutyl)amino]-N-[(3-nitrophenyl)methyl]-5-(trifluoromethyl)benzamideIC504000.0 [1], 6200.0 [2], 10000.0 [3], 39000.0 [4], 100000.0 [5]
3-[(2-Chloroacetyl)amino]-N-(2-chloropyridin-3-yl)-4-(2-phenylethyl)-5-(trifluoromethyl)benzamideIC5017000.0 [1], 22000.0 [2]
6-(Methylamino)nicotinamideIC50300.0 [1], 512.0 [2]
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamideIC5030000.0 [1]
4-MethoxybenzamideIC5030000.0 [1]
Bromo-deaza-SAHIC501500.0 [1]
6-MethylnicotinamideIC5010000.0 [1]
6-DimethylaminonicotinamideIC5030000.0 [1]
6-EthylnicotinamideIC5030000.0 [1]
2-Ethoxy-6-methylpyridine-3-carboxamideIC5030000.0 [1]
2-Methoxy-5-(2H-tetrazol-5-yl)pyridineIC5030000.0 [1]
(2S)-2-Amino-5-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[2-(3-carbamoylphenyl)ethyl]amino]pentanoic acidIC5014000.0 [1]
(2S)-2-Amino-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[2-(3-carbamoylphenyl)ethyl]amino]butanoic acidIC50160000.0 [1]
6-(Difluoromethoxy)pyridine-3-carboxamideIC5030000.0 [1]
4-Ethoxy-6-methylpyridine-3-carboxamideIC5030000.0 [1]
6-(Trideuteriomethoxy)pyridine-3-carboxamideIC50922.1 [1]
2-Chloro-N-[3-(1,3-dihydroisoindole-2-carbonyl)-5-(trifluoromethyl)phenyl]-N-(3-methylbutyl)acetamideIC502000.0 [1]
2-Chloro-N-[3-(5-methoxy-1,3-dihydroisoindole-2-carbonyl)-5-(trifluoromethyl)phenyl]-N-(3-methylbutyl)acetamideIC50870.0 [1]
3-[(2-Chloroacetyl)-(3-methylbutyl)amino]-5-(trifluoromethyl)-N-[(2,4,6-trifluorophenyl)methyl]benzamideIC501400.0 [1]
3-[(2-Chloroacetyl)-(3-methylbutyl)amino]-N-[(2,4-difluorophenyl)methyl]-5-(trifluoromethyl)benzamideIC501900.0 [1]
3-[(2-Chloroacetyl)amino]-N-(2-chloropyridin-3-yl)-5-(trifluoromethyl)benzamideIC5010000.0 [1]
3-[(2-Chloroacetyl)-(3-methylbutyl)amino]-N-[(4-fluorophenyl)methyl]-5-(trifluoromethyl)benzamideIC501500.0 [1]
3-[(2-Chloroacetyl)-(3-methylbutyl)amino]-N-(furan-2-ylmethyl)-5-(trifluoromethyl)benzamideIC501400.0 [1]
3-[(2-Chloroacetyl)-(3-methylbutyl)amino]-N-[(2,6-difluorophenyl)methyl]-5-(trifluoromethyl)benzamideIC501000.0 [1]
N-Benzyl-3-[(2-chloroacetyl)-(3-methylbutyl)amino]-5-(trifluoromethyl)benzamideIC501100.0 [1]
3-Fluoro-4-methoxybenzamideIC5030000.0 [1]
5-Methoxypyrazine-2-carboxamideIC5030000.0 [1]
6-Methoxy-3-PyridinecarboximidamideIC5030000.0 [1]
6-MethoxynicotinamideIC502365.0 [1]
6-(Methylsulfanyl)pyridine-3-carboxamideIC5030000.0 [1]
N-(6-Methoxypyridin-3-yl)acetamideIC5030000.0 [1]
6-(Trifluoromethyl)nicotinamideIC5030000.0 [1]
N-Ethyl-6-methoxypyridine-3-carboxamideIC5030000.0 [1]
3-Pyridinecarboxamide, 6-methoxy-4-methyl-IC50588.0 [1]
6-Methoxypyridazine-3-carboxamideIC50580.0 [1]
6-Methoxy-2-methylnicotinamideIC5030000.0 [1]
Items per page: 1 - 10 of 36
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References

This online tool may be cited as follows

MLA

"Quest Database™ Nicotinamide N-methyltransferase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/nicotinamide-n-methyltransferase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 8). Quest Database™ Nicotinamide N-methyltransferase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nicotinamide-n-methyltransferase-inhibitors-ic50-ki.
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