 | Cocaine | IC50 | 378.0 [1] |
| Cocaine | Ki | 264.0 [1] |
 | Desipramine | IC50 | 3.4 [1] |
| Desipramine | Ki | 0.6 [1], 2.1 [2], 3.4 [3], 5.11 [4] |
 | Duloxetine | IC50 | 5.0 [1] |
| Duloxetine | Ki | 7.94 [1] |
 | Fluoxetine | IC50 | 2000.0 [1] |
| Fluoxetine | Ki | 440.0 [1], 1292.0 [2], 1560.0 [3], 2000.0 [4] |
 | Atomoxetine | IC50 | 5.0 [1] |
 | Venlafaxine | IC50 | 535.0 [1] |
| Venlafaxine | Ki | 210.0 [1], 385.0 [2], 553.0 [3], 2685.0 [4] |
 | Protriptyline | IC50 | 1.1 [1], 7.1 [2], 17.0 [3] |
| Protriptyline | Ki | 2.0 [1], 2.1 [2], 2.3 [3], 6.8 [4] |
 | 2-[(2-Ethoxyphenoxy)-phenylmethyl]morpholine | IC50 | 3.2 [1] |
| 2-[(2-Ethoxyphenoxy)-phenylmethyl]morpholine | Ki | 1.1 [1], 5.0 [2] |
 | Nisoxetine | IC50 | 8.3 [1] |
| Nisoxetine | Ki | 1.6 [1], 6.0 [2] |
 | Bupropion | IC50 | 1850.0 [1] |
| Bupropion | Ki | 6970.0 [1] |
 | Venlafaxine hydrochloride | IC50 | 2550.0 [1] |
 | Mazindol | IC50 | 0.92 [1], 4.9 [2] |
| Mazindol | Ki | 11.3 [1], 13.5 [2], 18.0 [3] |
 | Midalcipran | IC50 | 0.79 [1], 77.0 [2], 5500.0 [3] |
| Midalcipran | Ki | 85.0 [1] |
 | 1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane | IC50 | 20.0 [1], 20.3 [2], 72.4 [3], 143.0 [4] |
| 1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane | Ki | 63.0 [1] |
 | Rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-azabicyclo[4.1.0]heptane | IC50 | 2.0 [1], 8.1 [2] |
| Rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-azabicyclo[4.1.0]heptane | Ki | 7.94 [1], 12.02 [2], 12.59 [3] |
 | Reboxetine | IC50 | 2.0 [1], 3.0 [2], 3.1 [3] |
| Reboxetine | Ki | 0.3 [1], 1.04 [2] |
 | Nomifensine | IC50 | 630.96 [1] |
| Nomifensine | Ki | 3.8 [1], 5.0 [2], 23.0 [3] |
 | Madam | IC50 | 100.0 [1] |
| Madam | Ki | 61.0 [1], 320.4 [2], 325.0 [3] |
 | Amitifadine | IC50 | 22.8 [1], 71.4 [2] |
| Amitifadine | Ki | 63.1 [1], 147.91 [2] |
 | 3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester | Ki | 1.4 [1], 11.2 [2], 22.0 [3], 36.0 [4] |
 | (R)-Sila-Venlafaxine | IC50 | 200.0 [1], 251.0 [2] |
 | 4-(3,4-Dimethoxy-phenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one | IC50 | 100000.0 [1] |
| 4-(3,4-Dimethoxy-phenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one | Ki | 100000.0 [1] |
 | (S)-N-(2,3-Dimethylbenzyl)-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amine | IC50 | 7.0 [1] |
 | (1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-(ethoxymethyl)-3-azabicyclo[3.1.0]hexane | IC50 | 0.16 [1] |
| (1S,5S,6S)-1-(3,4-Dichlorophenyl)-6-(ethoxymethyl)-3-azabicyclo[3.1.0]hexane | Ki | 0.5 [1], 1.58 [2] |
 | 2-[5-[3-(5-Fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]ethanamine | IC50 | 1930.0 [1], 5133.0 [2] |
| 2-[5-[3-(5-Fluoro-2-methoxyphenyl)propyl]oxolan-2-yl]ethanamine | Ki | 10600.0 [1], 30430.0 [2] |
 | Dimethyl-((2S,3S)-3-naphthalen-2-yl-bicyclo[2.2.1]hept-2-ylmethyl)-amine | IC50 | 25.0 [1] |
| Dimethyl-((2S,3S)-3-naphthalen-2-yl-bicyclo[2.2.1]hept-2-ylmethyl)-amine | Ki | 152.0 [1] |
 | (1S,2R)-1-(1H-Indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol | IC50 | 23.0 [1], 28.0 [2] |
 | (cis)-2-(5-Bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one | IC50 | 100000.0 [1] |
| (cis)-2-(5-Bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one | Ki | 39119.0 [1] |
 | (2S)-4-[3-(2-Fluorophenyl)-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-1-(methylamino)butan-2-ol | IC50 | 1.0 [1], 2.0 [2], 4.0 [3], 6.0 [4] |
 | (2R)-4-[3-(2-Fluorophenyl)-2,2-dioxo-2lambda6,1,3-benzothiadiazol-1-yl]-1-(methylamino)butan-2-ol | IC50 | 3.0 [1], 4.0 [2], 9.0 [3] |
 | Methylphenidate | IC50 | 61.0 [1] |
| Methylphenidate | Ki | 340.0 [1], 660.0 [2] |
 | Citalopram | Ki | 2178.0 [1], 6190.0 [2], 1000000.0 [3] |
 | Paroxetine | IC50 | 100.0 [1] |
| Paroxetine | Ki | 86.0 [1], 90.0 [2] |
 | 3,4-Methylenedioxymethamphetamine | IC50 | 405.0 [1], 1995.26 [2] |
 | Sertraline | IC50 | 825.0 [1] |
| Sertraline | Ki | 976.6 [1] |
 | Tenamfetamine | IC50 | 266.0 [1], 3162.28 [2] |
 | Vanoxerine | IC50 | 79.0 [1], 110.0 [2] |
 | Methyl (1R,2S,3S,5R)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | IC50 | 834.0 [1] |
| Methyl (1R,2S,3S,5R)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | Ki | 503.0 [1], 635.0 [2] |
 | 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine | IC50 | 165.0 [1], 1261.0 [2] |
| 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine | Ki | 630.0 [1] |
 | 2-((2-((Dimethylamino)methyl)phenyl)thio)-5-iodophenylamine | Ki | 699.0 [1], 1352.0 [2] |
 | Benzonitrile, 3-amino-4-((2-((dimethylamino)methyl)phenyl)thio)- | Ki | 1000.0 [1], 1350.0 [2], 5127.0 [3] |
 | N,N-Diallyl-5-methoxytryptamine | IC50 | 42657.95 [1] |
| N,N-Diallyl-5-methoxytryptamine | Ki | 10000.0 [1] |
 | (S)-Venlafaxine | IC50 | 149.0 [1], 754.0 [2] |
 | 3-Amino-4-[[2-[(dimethylamino)methyl]phenyl]thio]benzenemethanol | Ki | 303.0 [1], 787.4 [2] |
 | BMS-505130 free base | IC50 | 9200.0 [1] |
| BMS-505130 free base | Ki | 4600.0 [1] |
 | Morpholine, 2-((S)-(2-methoxyphenoxy)phenylmethyl)-, (2S)- | Ki | 0.95 [1], 7.93 [2] |
 | 6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol | IC50 | 4.9 [1] |
| 6-(4-Chloro-phenyl)-2,3,4,6-tetrahydro-pyrimido[2,1-a]isoindol-6-ol | Ki | 18.0 [1], 18.2 [2] |
 | 2-Methyl-N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propanamide | IC50 | 14.0 [1] |
| 2-Methyl-N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propanamide | Ki | 6.0 [1] |
 | (1S,5R)-1-(3,4-Dichlorophenyl)-3-azabicyclo(3.1.0)hexane | IC50 | 103.0 [1] |
| (1S,5R)-1-(3,4-Dichlorophenyl)-3-azabicyclo(3.1.0)hexane | Ki | 58.88 [1], 794.33 [2] |
 | (S)-N-(2,3-Dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide | IC50 | 23.0 [1] |
| (S)-N-(2,3-Dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide | Ki | 52.0 [1] |
 | 1-[(1R)-2-(2-Ethoxyphenyl)-1-phenylethyl]piperazine | IC50 | 16.0 [1], 18.0 [2] |
| 1-[(1R)-2-(2-Ethoxyphenyl)-1-phenylethyl]piperazine | Ki | 12.0 [1] |
 | Methyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate | Ki | 11000.0 [1], 28000.0 [2] |
 | (R)-3-(4-(Dimethylamino)cyclohex-1-enyl)-1H-indole-5-carbonitrile | IC50 | 390.0 [1] |
 | Silacyclohexan-1-ol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]- | IC50 | 109.0 [1] |
 | [(2S,3S)-3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine | IC50 | 44.0 [1] |
| [(2S,3S)-3-(3-Chloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine | Ki | 51.0 [1] |
 | 2-(Tert-butylamino)-1-(3-chlorophenyl)butan-1-one | IC50 | 607.0 [1], 969.0 [2] |
| 2-(Tert-butylamino)-1-(3-chlorophenyl)butan-1-one | Ki | 3195.0 [1] |
 | 2-(Tert-butylamino)-1-(3-chlorophenyl)pentan-1-one | IC50 | 370.0 [1], 472.0 [2] |
| 2-(Tert-butylamino)-1-(3-chlorophenyl)pentan-1-one | Ki | 1171.0 [1] |
 | 1-(3-Bromophenyl)-2-(tert-butylamino)propan-1-one | IC50 | 5600.0 [1], 6500.0 [2] |
| 1-(3-Bromophenyl)-2-(tert-butylamino)propan-1-one | Ki | 7140.0 [1] |
 | 1-(3-Chlorophenyl)-2-(piperidin-1-yl)propan-1-one | IC50 | 2520.0 [1], 4798.0 [2] |
| 1-(3-Chlorophenyl)-2-(piperidin-1-yl)propan-1-one | Ki | 4760.0 [1] |
 | 1-(3-Chlorophenyl)-2-(dimethylamino)propan-1-one | IC50 | 1260.0 [1], 1520.0 [2] |
| 1-(3-Chlorophenyl)-2-(dimethylamino)propan-1-one | Ki | 3090.0 [1] |
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