Name: NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor) Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor) Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Imatinib	IC50	30000.0 ^[1], 100000.0 ^[2]
	Bosutinib	IC50	150.0 ^[1], 200.0 ^[2], 10000.0 ^[3], 20000.0 ^[4]
	6-(2,6-Dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one	IC50	2500.0 ^[1], 3000.0 ^[2], 30000.0 ^[3]
	N-[2-[2-[4-[4-[(2S)-2-Hydroxypropyl]piperazin-1-yl]-2-methoxyanilino]pyrrolo[2,1-f][1,2,4]triazin-7-yl]phenyl]-N-methylmethanesulfonamide	IC50	60.0 ^[1]
	5-(1,3-Benzodioxol-5-yl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxo-1H-pyridine-3-carboxamide	IC50	3600.0 ^[1], 6500.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 14 Dec. 2025, https://www.aatbio.com/data-sets/npm-alk-nucleophosmin-alk-tyrosine-kinase-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 14). Quest Database™ NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/npm-alk-nucleophosmin-alk-tyrosine-kinase-receptor-inhibitors-ic50-ki.
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