Nuclear factor NF-kappa-B p105 subunit Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Rocaglamide	IC50	75.0 [1], 2000.0 [2]
	Psoralen	IC50	3000.0 [1]
	4-Methylumbelliferone	IC50	200000.0 [1]
	Andrographolide	IC50	49600.0 [1]
	alpha-Mangostin	IC50	20000.0 [1]
	Angelicin	IC50	2500.0 [1]
	(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one	IC50	8200.0 [1]
	2-Hydroxycinnamic acid	IC50	50000.0 [1]
	Cyqualon	IC50	4400.0 [1]
	Gartanin	IC50	20000.0 [1]
	Cycloartobiloxanthone	IC50	10000.0 [1]
	N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	50.0 [1]
	2-(4,5,6-Trihydroxy-3-oxoxanthen-9-yl)benzenesulfonic acid	IC50	10000.0 [1]
	8-Desoxygartanin	IC50	20000.0 [1]
	9-Hydroxycalabaxanthone	IC50	20000.0 [1]
	beta-Mangostin	IC50	7500.0 [1]
	(1E,4E)-1,5-Di(pyridin-3-yl)penta-1,4-dien-3-one	IC50	3400.0 [1]
	Garcinone D	IC50	20000.0 [1]
	3-(3-Fluoro-4-methoxyphenyl)-5-phenyl-7-furo[3,2-g][1]benzopyranone	IC50	20000.0 [1]
	2,4-Dichloro-6-(3-nitroanilino)-1,3,5-triazine	IC50	119000.0 [1]
	2,4-Dichloro-6-(4-ethoxyanilino)-s-triazine	IC50	35200.0 [1]
	Artobiloxanthone	IC50	2300.0 [1]
	1,5-Bis(2-hydroxyphenyl)penta-1,4-dien-3-one	IC50	4200.0 [1]
	[4-[(1E,4E)-5-(4-Acetyloxy-3-methoxyphenyl)-3-oxopenta-1,4-dienyl]-2-methoxyphenyl] acetate	IC50	5400.0 [1]
	(1E,4E)-1,5-Bis(2,5-dimethoxyphenyl)penta-1,4-dien-3-one	IC50	6400.0 [1]
	1,5-Bis[2-(trifluoromethyl)phenyl]-1,4-pentadiene-3-one	IC50	5000.0 [1]
	3-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-5-methoxy-phenol	IC50	10000.0 [1]
	8-(4-Methoxy-benzoyl)-4-methyl-9-phenyl-furo[2,3-h]chromen-2-one	IC50	60000.0 [1]
	[(1R,2R,4As,5R,8aS)-2-acetyloxy-1,4a-dimethyl-6-methylidene-5-[(2E)-2-(2-oxofuran-3-ylidene)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl acetate	IC50	11100.0 [1]
	(4,6-Dichloro-[1,3,5]triazin-2-yl)-(4-isopropyl-phenyl)-amine	IC50	74400.0 [1]
	Artorigidin A	IC50	10000.0 [1]
	3,9-Dihydroxy-5,10-dimethoxy-2,2-dimethyl-11-(3-methylbut-2-enyl)-3,4-dihydropyrano[2,3-a]xanthen-12-one	IC50	20000.0 [1]
	2-(2,7-Dibromo-4,5,6-trihydroxy-3-oxoxanthen-9-yl)benzenesulfonic acid	IC50	30000.0 [1]
	N-[3-(Butylcarbamoyl)-5-(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-Chloro-N-(3,4,5-trichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	900.0 [1]
	N-(3,5-Dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-Chloro-4-(trifluoromethyl)-N-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxamide	IC50	380.0 [1]
	2-Chloro-N-(3,5-dichlorophenyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	2300.0 [1]
	2-(Cyclohexylamino)-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	N-[3-Carbamoyl-5-(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	5000.0 [1]
	N-Benzyl-2-chloro-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	2700.0 [1]
	2-Anilino-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	N-(3,5-Dichlorophenyl)-2-(dimethylamino)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	Cyclohexyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate	IC50	1800.0 [1]
	Hexyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate	IC50	620.0 [1]
	Diethoxyphosphorylmethyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate	IC50	4600.0 [1]
	Butyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate	IC50	170.0 [1]
	N-(3,5-Dichlorophenyl)-2-methoxy-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-(Butylamino)-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-Chloro-N-(2,6-dimethylphenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	N-(3,5-Dichlorophenyl)-2-oxo-6-(trifluoromethyl)-1H-pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-Chloro-N-(2,6-dichloropyrimidin-4-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	800.0 [1]
	N-(3,5-Dichlorophenyl)-2-piperidin-1-yl-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	5000.0 [1]
	2-(Benzylamino)-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-Chloro-N-(3-methyl-1,2-oxazol-5-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	4000.0 [1]
	2-Chloro-N-(5-methylthiophen-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	2300.0 [1]
	2-Amino-N-(3,5-dichlorophenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	2-Chloro-N-(3,5-dimethoxyphenyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	1200.0 [1]
	Octyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate	IC50	1800.0 [1]
	N-Butyl-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	Ethyl 3-[[2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl]amino]-5-(trifluoromethyl)benzoate	IC50	280.0 [1]
	(1E,4E)-1,5-Di(pyridin-4-yl)penta-1,4-dien-3-one	IC50	3500.0 [1]
	(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-4-methylhepta-1,4,6-trien-3-one	IC50	6700.0 [1]
	2-((2-Methoxyethyl)amino)-6-methyl-3-(3,4,5-trimethoxyphenyl)-4H-furo[3,2-c]chromen-4-one	IC50	40000.0 [1]
	4,6-Dichloro-N-(4-chlorophenyl)-1,3,5-triazin-2-amine	IC50	110000.0 [1]
	4,6-Dichloro-N-(4-nitrophenyl)-1,3,5-triazin-2-amine	IC50	300000.0 [1]
	3-(1,3-Benzodioxol-5-yl)-5-phenyl-7H-furo[3,2-g]chromen-7-one	IC50	20000.0 [1]
	N5-(3,5-Dichlorophenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	500.0 [1]
	2-Chloro-N-phenyl-4-(trifluoromethyl)pyrimidine-5-carboxamide	IC50	10000.0 [1]
	Artoheterophyllin B	IC50	10000.0 [1]
	Artoristilbene	IC50	10000.0 [1]
	Cratoxyxanthone	IC50	20000.0 [1]
	11-Hydroxy-1-isomangostin	IC50	20000.0 [1]
	Artonin O	IC50	10000.0 [1]
	4-[(7-Hydroxy-4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-9-yl)oxymethyl]benzoic acid	IC50	5000.0 [1]
	(4,6-Dichloro-[1,3,5]triazin-2-yl)-m-tolyl-amine	IC50	19000.0 [1]
	(1E,4Z,6E)-4-Benzyl-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one	IC50	7600.0 [1]
	(1E,6E)-1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-7-(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione	IC50	8200.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 78 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Nuclear factor NF-kappa-B p105 subunit Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p105-subunit-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Nuclear factor NF-kappa-B p105 subunit Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p105-subunit-inhibitors-ic50-ki.
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