Nuclear factor NF-kappa-B p65 subunit Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Rocaglamide	IC50	70.0 [1], 75.0 [2], 80.0 [3], 4000.0 [4]
	alpha-Mangostin	IC50	10000.0 [1], 15900.0 [2]
	Resveratrol	IC50	20000.0 [1]
	Oleanolic acid	IC50	2400.0 [1]
	Ursolic acid	IC50	31.0 [1]
	Betulinic acid	IC50	10000.0 [1]
	(E)-3-Tosylacrylonitrile	IC50	3000.0 [1]
	Betulin	IC50	8800.0 [1]
	Silvestrol	IC50	20000.0 [1]
	Uvaol	IC50	10000.0 [1]
	Erythrodiol	IC50	10000.0 [1]
	5Z-7-Oxozeaenol	IC50	250.0 [1]
	Loliolide	IC50	10000.0 [1]
	Combretum caffrum	IC50	1600.0 [1]
	4-Dimethylaminostilbene	IC50	150.0 [1]
	5E-7-Oxozeaenol	IC50	11500.0 [1]
	Incensole acetate	IC50	100000.0 [1]
	Vomifoliol	IC50	10000.0 [1]
	Gartanin	IC50	19000.0 [1]
	Cycloartobiloxanthone	IC50	10000.0 [1]
	Alphitolic acid	IC50	8700.0 [1]
	8-(4-Benzenesulfonylamino)quinoline	IC50	10000.0 [1]
	8-Desoxygartanin	IC50	11300.0 [1]
	9-Hydroxycalabaxanthone	IC50	20000.0 [1]
	Sideroxylin	IC50	10000.0 [1]
	beta-Mangostin	IC50	12100.0 [1]
	Garcinone D	IC50	3200.0 [1]
	5H-Quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	1000.0 [1]
	4-Methyl-2-nitro-N-quinolin-8-ylbenzenesulfonamide	IC50	2100.0 [1]
	(E)-3,4'-Dimethoxystilbene	IC50	600.0 [1]
	2-Nitro-N-quinolin-8-ylbenzenesulfonamide	IC50	3200.0 [1]
	(4S,9S,10S,12E)-9,10,18-Trihydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	IC50	50000.0 [1]
	1,3,7-Trihydroxy-2,4-diisoprenylxanthone	IC50	2900.0 [1]
	2-Amino-N-quinolin-8-yl-benzenesulfonamide	IC50	2000.0 [1]
	4-Nitro-N-(8-quinolyl)benzenesulfonamide	IC50	1500.0 [1]
	Artobiloxanthone	IC50	3700.0 [1]
	Zeaenol	IC50	50000.0 [1]
	(2E)-1-(3-Bromophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one	IC50	50000.0 [1]
	3,4-Dihydroxy-4'-methoxystilbene	IC50	600.0 [1]
	Cochinchinone A	IC50	10000.0 [1]
	2'''-Episilvestrol	IC50	20000.0 [1]
	Nik smi1	IC50	20000.0 [1]
	NF-kB Activation Inhibitor IV	IC50	150.0 [1]
	3,6-Dimethylmangostin	IC50	10000.0 [1]
	Di-O-acetylmangostin	IC50	10000.0 [1]
	(1R,3As,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid	IC50	5400.0 [1]
	N-(3-(4-(3-Aminopropylamino)butylamino)propyl)dodecane-1-sulfonamide	IC50	340.0 [1]
	(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy-	IC50	10000.0 [1]
	(1R,3As,5aS,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-3a-methoxycarbonyl-5b,8,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-5a-carboxylic acid	IC50	1500.0 [1]
	1-Chloro-2-[(E)-2-(4-methoxyphenyl)ethenyl]benzene	IC50	1500.0 [1]
	3-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-5-methoxy-phenol	IC50	10000.0 [1]
	N-(3-(4-(3-Aminopropylamino)butylamino)propyl)hexadecane-1-sulfonamide	IC50	230.0 [1]
	N-(3-(4-(3-Aminopropylamino)butylamino)propyl)decane-1-sulfonamide	IC50	310.0 [1]
	N-(3-(4-(3-Aminopropylamino)butylamino)propyl)octadecane-1-sulfonamide	IC50	2100.0 [1]
	N-(2-Methylquinolin-8-yl)-2-nitrobenzenesulfonamide	IC50	3800.0 [1]
	2-Amino-N-(2-methylquinolin-8-yl)benzenesulfonamide	IC50	2800.0 [1]
	N-(2-Methylquinolin-8-yl)-2-nitro-4-(trifluoromethyl)benzenesulfonamide	IC50	1100.0 [1]
	3-Methyl-9-(trifluoromethyl)-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	1200.0 [1]
	5-Bromo-N-(2-methylquinolin-8-yl)thiophene-2-sulfonamide	IC50	1400.0 [1]
	9-Trifluoromethyl-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide	IC50	1000.0 [1]
	3-Methyl-6,6-dioxo-5H-quinolino[8,7-c][1,2]benzothiazin-9-ol	IC50	10000.0 [1]
	2-Amino-N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide	IC50	1000.0 [1]
	2-Nitro-N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamide	IC50	3700.0 [1]
	9-Fluoro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide	IC50	1700.0 [1]
	9-Methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	600.0 [1]
	9-Methoxy-3-methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	2500.0 [1]
	9-Chloro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide	IC50	1100.0 [1]
	11-Methoxy-3,9-dimethyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	900.0 [1]
	N-(2-Methylquinolin-8-yl)-3-nitrobenzenesulfonamide	IC50	900.0 [1]
	5-Chloro-N-(2-methylquinolin-8-yl)thiophene-2-sulfonamide	IC50	1000.0 [1]
	9-Methoxy-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide	IC50	1000.0 [1]
	N-(6-Methoxyquinolin-8-yl)-4-methyl-2-nitrobenzenesulfonamide	IC50	2100.0 [1]
	11-Methoxy-9-methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	1200.0 [1]
	(E)-4-Ethoxystilbene	IC50	300.0 [1]
	5-Bromo-N-quinolin-8-ylthiophene-2-sulfonamide	IC50	1100.0 [1]
	1-Fluoro-3-[(E)-2-(4-methoxyphenyl)ethenyl]benzene	IC50	1100.0 [1]
	2-Methoxy-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide	IC50	2500.0 [1]
	4-Methoxy-N-(2-methylquinolin-8-yl)-2-nitrobenzenesulfonamide	IC50	1000.0 [1]
	Artorigidin A	IC50	2000.0 [1]
	3,9-Dihydroxy-5,10-dimethoxy-2,2-dimethyl-11-(3-methylbut-2-enyl)-3,4-dihydropyrano[2,3-a]xanthen-12-one	IC50	20000.0 [1]
	5-Chloro-N-(quinolin-8-yl)thiophene-2-sulfonamide	IC50	1300.0 [1]
	5-Nitro-2-methyl-N-(8-quinolinyl)benzenesulfonamide	IC50	1600.0 [1]
	N-(Quinolin-8-yl)thiophene-2-sulfonamide	IC50	3600.0 [1]
	(1R,3As,5aR,5bR,7aR,9R,10R,11aR,11bR,13aR,13bR)-10-hydroxy-9-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid	IC50	4700.0 [1]
	3-[(E)-2-(4-Methoxyphenyl)ethenyl]benzene-1,2-diol	IC50	500.0 [1]
	(2S)-6-[(1R)-1-[2,4-Bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]phenyl]-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propyl]-8-[(1S)-1-[2,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]phenyl]-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propyl]-5,7-dihydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one	IC50	19300.0 [1]
	[1,6-Diacetyloxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9-oxoxanthen-3-yl] acetate	IC50	10000.0 [1]
	(1S,2R,4As,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-(4-chlorobenzoyl)oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid	IC50	10000.0 [1]
	(1R,3As,5aS,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a-(hydroxymethyl)-5b,8,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid	IC50	10000.0 [1]
	N-(6-Methoxy-2-methylquinolin-8-yl)-4-methylbenzenesulfonamide	IC50	10000.0 [1]
	2-[(E)-2-Phenylethenyl]naphthalene	IC50	1300.0 [1]
	(1R,3As,5aS,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5b,8,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a,5a-dicarboxylic acid	IC50	10000.0 [1]
	Artoheterophyllin B	IC50	10000.0 [1]
	3-Methyl-4'-methoxystilbene	IC50	800.0 [1]
	15-O-Desmethyl-(5Z)-7-oxozeaenol	IC50	750.0 [1]
	Artoristilbene	IC50	10000.0 [1]
	Cratoxyxanthone	IC50	20000.0 [1]
	11-Hydroxy-1-isomangostin	IC50	20000.0 [1]
	Artonin O	IC50	10000.0 [1]
	(1R,2R,5S,8S,10R,11S,14R,15R,20S)-5-Hydroxy-8-(2-hydroxypropan-2-yl)-1,2,15,19,19-pentamethyl-9-oxapentacyclo[12.8.0.02,11.05,10.015,20]docosan-18-one	IC50	20000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Nuclear factor NF-kappa-B p65 subunit Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p65-subunit-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Nuclear factor NF-kappa-B p65 subunit Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nuclear-factor-nf-kappa-b-p65-subunit-inhibitors-ic50-ki.
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