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Nucleotide-binding oligomerization domain-containing protein 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Nodinitib-1IC50560.0 [1]
1-(4-Chlorophenyl)sulfonyl-2-benzimidazolamineIC5090.0 [1]
Ethyl 4-[[4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)benzoyl]amino]benzoateIC50150.0 [1]
Cyclopropyl-[5-[4-(4-methoxyphenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]methanoneIC50510.0 [1]
1-(4-Chlorophenylmethyl)-2-aminobenzimidazoleIC507700.0 [1]
1-[5-[4-(4-Chlorophenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]propan-1-oneIC501010.0 [1]
Cyclopropyl-[2-methyl-5-[4-(4-nitrophenyl)piperazino]sulfonyl-indolin-1-yl]methanoneIC50260.0 [1]
CID 44182149IC50240.0 [1]
CID 44229055IC5080.0 [1]
1-(Toluene-4-sulfonyl)-1H-benzoimidazoleIC506300.0 [1]
1-[4-[4-(1-Acetyl-2-methyl-indolin-5-yl)sulfonylpiperazino]phenyl]ethanoneIC504420.0 [1]
2-Methyl-1-(4-methylphenyl)sulfonylbenzimidazoleIC5020000.0 [1]
(2-Aminobenzimidazol-1-yl)-(4-fluorophenyl)methanoneIC5018000.0 [1]
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-p-tolyl-benzamideIC503440.0 [1]
N-(4-Chloro-phenyl)-4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-benzamideIC50830.0 [1]
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-ethoxy-phenyl)-benzamideIC501130.0 [1]
4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-fluoro-phenyl)-benzamideIC503110.0 [1]
2-Methyl-5-{[4-(4-nitrophenyl)piperazin-1-yl]sulfonyl}-1-propionylindolineIC501870.0 [1]
CID 20901603IC505600.0 [1]
Cyclopropyl-[2-methyl-5-(4-phenylpiperazino)sulfonyl-indolin-1-yl]methanoneIC5020000.0 [1]
1-[4-[4-[1-(Cyclopropanecarbonyl)-2-methyl-indolin-5-yl]sulfonylpiperazino]phenyl]ethanoneIC5010260.0 [1]
7-[(E)-But-2-enyl]-3-methyl-8-(3-phenylpropylsulfanyl)purine-2,6-dioneIC501540.0 [1]
3-Methyl-7-pentyl-8-(2-phenylethylthio)purine-2,6-dioneIC50940.0 [1]
3-Methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purine-2,6-dioneIC501220.0 [1]
7-Benzyl-3-methyl-8-nitropurine-2,6-dioneIC50790.0 [1]
1-(Phenylsulfonyl)-1H-benzimidazol-2-amineIC502200.0 [1]
1-((4-Nitrophenyl)sulfonyl)-1H-benzimidazol-2-amineIC5014000.0 [1]
1-(4-Methoxyphenyl)sulfonyl-2-benzimidazolamineIC502700.0 [1]
5,6-Dimethyl-1-(4-methylphenyl)sulfonyl-2-benzimidazolamineIC5020000.0 [1]
1-(2-Aminobenzimidazol-1-yl)-2-phenylethanoneIC5020000.0 [1]
4-(3,4-Dihydroisoquinolin-2(1H)-ylmethyl)-N-(4-methoxyphenyl)benzamideIC50510.0 [1]
1-Acetyl-5-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2-methylindolineIC503630.0 [1]
N-[2-[1-[2-(2,3-Dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]-N-methylbenzamideIC50400.0 [1]
(2-Aminobenzimidazol-1-yl)-(2,4-dichlorophenyl)methanoneIC502800.0 [1]
N-(4-Bromophenyl)-4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)benzamideIC501030.0 [1]
1-Pentyl-4-phenylmethoxybenzimidazol-2-amineIC5010000.0 [1]
4-Benzyl-1-pentylbenzimidazol-2-amineIC5010000.0 [1]
3-Pentylbenzo[f]benzimidazol-2-amineIC5010000.0 [1]
1-Pentylbenzo[e]benzimidazol-2-amineIC5010000.0 [1]
N-[2-[1-[2-Oxo-2-(3-propan-2-ylanilino)ethyl]benzimidazol-2-yl]ethyl]benzamideIC50800.0 [1]
N-[2-[1-[2-(Naphthalen-2-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]benzamideIC501600.0 [1]
N-[2-[5-Chloro-1-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]benzamideIC501300.0 [1]
N-[2-[1-[2-(2,3-Dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]naphthalene-2-carboxamideIC503400.0 [1]
N-[2-[1-[2-(2,3-Dihydro-1H-inden-5-ylamino)-2-oxoethyl]benzimidazol-2-yl]ethyl]-N-methylnaphthalene-2-carboxamideIC50200.0 [1]
N-(1-Pentylbenzimidazol-2-yl)acetamideIC5010000.0 [1]
1-Pentyl-4-phenylbenzimidazol-2-amineIC5010000.0 [1]
Methyl 3-[(3S)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC50580.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-[(3-fluorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501370.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-bromophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC50580.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-(naphthalen-2-ylmethoxy)acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501610.0 [1]
Methyl 3-[(3R)-7-[4-chloro-3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC502900.0 [1]
3-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]-N-propylpropanamideIC502360.0 [1]
3-[(3R)-7-[3-(Dimethylamino)phenoxy]-8-[[2-[(4-fluorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]-N-propylpropanamideIC502810.0 [1]
N,N-Dibutyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC501300.0 [1]
N-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-3-(3-oxo-3-pyrrolidin-1-ylpropyl)-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-phenylmethoxyacetamideIC502370.0 [1]
Methyl 3-[(3R)-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-7-[2,4,5-trichloro-3-(dimethylamino)phenoxy]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501330.0 [1]
Methyl 3-[(3R)-8-[[2-[(3-chlorophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501290.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-cyanophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC503990.0 [1]
N-Butyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC501290.0 [1]
N-Cyclopropyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC508620.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-2,5-dioxo-7-(3-pyrrolidin-1-ylphenoxy)-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501390.0 [1]
2-[(4-Chlorophenyl)methoxy]-N-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3-(3-oxo-3-piperidin-1-ylpropyl)-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]acetamideIC501060.0 [1]
3-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]-N,N-diethylpropanamideIC501270.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC50940.0 [1]
N-[(3S)-7-[3-(Dimethylamino)phenoxy]-3-methyl-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamideIC501930.0 [1]
N-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-3-(3-oxo-3-piperidin-1-ylpropyl)-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-phenylmethoxyacetamideIC501110.0 [1]
Methyl 3-[(3R)-7-[3-(dimethylamino)phenoxy]-8-[[2-[(4-fluorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC502360.0 [1]
N-[(3R)-3-[3-(4,4-Difluoropiperidin-1-yl)-3-oxopropyl]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamideIC50430.0 [1]
N-Tert-butyl-3-[(3R)-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanamideIC501110.0 [1]
Methyl 3-[(3R)-7-[4-chloro-3-(dimethylamino)phenoxy]-8-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501550.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-tert-butylphenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501960.0 [1]
Methyl 3-[(3R)-8-[[2-[(3-bromophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501330.0 [1]
3-[(3R)-7-[3-(Dimethylamino)phenoxy]-2,5-dioxo-8-[(2-phenylmethoxyacetyl)amino]-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]-N,N-dimethylpropanamideIC504950.0 [1]
Methyl 3-[(3R)-8-[[2-[(3,4-difluorophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC501160.0 [1]
Methyl 3-[(3R)-8-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-7-[3-(dimethylamino)phenoxy]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateIC50610.0 [1]
N-[(3R)-7-[3-(Dimethylamino)phenoxy]-3-[3-(4-fluoropiperidin-1-yl)-3-oxopropyl]-2,5-dioxo-3,4-dihydro-1H-1,4-benzodiazepin-8-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamideIC50580.0 [1]
1-[4-[4-(1-Acetylindolin-5-yl)sulfonylpiperazino]phenyl]ethanoneIC5017400.0 [1]
1-[5-[4-(4-Acetylphenyl)piperazino]sulfonylindolin-1-yl]propan-1-oneIC5020000.0 [1]
1-Acetyl-5-{[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl}-2-methylindolineIC502570.0 [1]
5-{[4-(4-Chlorophenyl)piperazin-1-yl]sulfonyl}-1-propionylindolineIC5020000.0 [1]
N-(4-Methoxyphenyl)-4-(piperidin-1-ylmethyl)benzamideIC5020000.0 [1]
1-[2-Methyl-5-(4-phenylpiperazino)sulfonyl-indolin-1-yl]ethanoneIC5011150.0 [1]
1-[4-[4-[1-(Cyclopropanecarbonyl)indolin-5-yl]sulfonylpiperazino]phenyl]ethanoneIC5020000.0 [1]
1-[5-[4-(4-Nitrophenyl)piperazino]sulfonylindolin-1-yl]ethanoneIC5020000.0 [1]
N-(4-Ethoxyphenyl)-4-(piperidin-1-ylmethyl)benzamideIC5020000.0 [1]
N-(4-Fluorophenyl)-4-(piperidin-1-ylmethyl)benzamideIC5020000.0 [1]
CID 42370913IC5020000.0 [1]
CID 44182107IC5020000.0 [1]
CID 44182108IC5020000.0 [1]
1-[2-Methyl-5-[4-(4-nitrophenyl)piperazino]sulfonyl-indolin-1-yl]ethanoneIC501700.0 [1]
1-[5-[4-(4-Acetylphenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]propan-1-oneIC502000.0 [1]
1-[2-Methyl-5-[4-(p-tolyl)piperazino]sulfonyl-indolin-1-yl]ethanoneIC505760.0 [1]
Cyclopropyl-[2-methyl-5-[4-(p-tolyl)piperazino]sulfonyl-indolin-1-yl]methanoneIC5020000.0 [1]
CID 44182148IC5020000.0 [1]
CID 44182150IC5020000.0 [1]
CID 44229052IC5020000.0 [1]
CID 44229053IC501610.0 [1]
CID 44229054IC5020000.0 [1]
CID 44229056IC5020000.0 [1]
Ethyl 4-[[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]benzoyl]amino]benzoateIC5010600.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Nucleotide-binding oligomerization domain-containing protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/nucleotide-binding-oligomerization-domain-containing-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Nucleotide-binding oligomerization domain-containing protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/nucleotide-binding-oligomerization-domain-containing-protein-1-inhibitors-ic50-ki.
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