Opioid growth factor receptor-like protein 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4-[(1R,5S)-9-(3-Bicyclo[3.3.1]nonanyl)-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	2.4 [1], 178.0 [2]
	4-[(1R,5S)-8-Cycloundecyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	9.0 [1]
	4-[(1R,5S)-8-Cyclododecyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	43.1 [1]
	4-[(1R,5S)-8-(3-Bicyclo[3.3.1]nonanyl)-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	5.7 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-11,15-dimethoxy-16-(phenylmethoxymethyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	532.0 [1], 859.27 [2]
	4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	12.6 [1], 299.0 [2]
	(2S)-2-[[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]amino]-3-hydroxypropanoic acid	Ki	8.2 [1], 285.0 [2]
	2-[[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]amino]acetic acid	Ki	61.4 [1], 1716.0 [2]
	2-[[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]amino]acetamide	Ki	6.42 [1], 233.7 [2]
	4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxo-N-(6-oxo-1H-pyridin-3-yl)quinoxaline-2-carboxamide	Ki	7.5 [1], 103.0 [2]
	3-Oxo-4-[(1R,5S)-8-(3-tricyclo[3.3.1.03,7]nonanyl)-8-azabicyclo[3.2.1]octan-3-yl]quinoxaline-2-carboxylic acid	Ki	15.4 [1], 364.0 [2]
	1-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-[[(2R)-2,3-dihydroxypropyl]amino]quinoxalin-2-one	Ki	6.5 [1], 288.0 [2]
	4-[(1R,5S)-8-(1-Adamantyl)-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	89.9 [1], 275.0 [2]
	Cebranopadol	Ki	22.0 [1]
	N-[(E)-(2,3-Dihydroxyphenyl)methylideneamino]-4-[(4,6-dimethylpyrimidin-2-yl)sulfanylmethyl]benzamide	Ki	836.0 [1]
	N,N-Dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	0.6 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-16-[(3,4-dichlorophenyl)methoxymethyl]-11,15-dimethoxy-5-methyl-13-oxa-5-azoniahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	20000.0 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-11,15-dimethoxy-5-methyl-16-[(4-methylphenyl)methoxymethyl]-13-oxa-5-azoniahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	20000.0 [1]
	3-Amino-1-[4-[(1R,5S)-9-[(1S,6R)-8-bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-3-carboxylic acid	Ki	0.22 [1]
	(2S)-1-[4-[(1R,5S)-9-[(1S,5R)-3-Bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	27.1 [1]
	1-[4-[(1R,5S)-9-[(1S,6R)-8-Bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]-3-(dimethylamino)azetidine-3-carboxylic acid	Ki	0.34 [1]
	(2S,3R)-1-[4-[(1R,5S)-9-[(1S,6R)-8-Bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]-3-(methylamino)azetidine-2-carboxylic acid	Ki	1.98 [1]
	(2R)-1-[4-[(1R,5S)-8-[(1S,5R)-7-Methyl-3-bicyclo[3.3.1]nonanyl]-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	43.0 [1]
	2-[1-[4-[(1R,5S)-9-[(1S,5R)-7-Methyl-3-bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidin-3-yl]acetic acid	Ki	1.03 [1]
	(2R)-1-[4-[(1R,5S)-9-[(1S,5R)-7-Methyl-3-bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	9.8 [1]
	(2S)-1-[4-[(1S,5R)-9-[(1S,5R)-3-Bicyclo[3.3.1]nonanyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	294.0 [1]
	(2S,3R)-1-[4-[(1R,5S)-9-[(1S,5R)-3-Bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]-3-(dimethylamino)azetidine-2-carboxylic acid	Ki	23.0 [1]
	(2R)-1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	0.89 [1]
	(2S)-1-[4-[(1R,5S)-8-[(1S,5R)-7-Methyl-3-bicyclo[3.3.1]nonanyl]-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	19.2 [1]
	(2S)-1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	7.44 [1]
	1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxalin-2-yl]azetidine-3-carboxylic acid	Ki	381.0 [1]
	(2S,3S)-1-[4-[(1R,5S)-9-[(1S,5R)-3-Bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]-3-methoxyazetidine-2-carboxylic acid	Ki	11.9 [1]
	(2S)-1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	55.5 [1]
	(2S)-1-[4-[(1S,5R)-9-[2-[(1S,2S,5S)-6,6-Dimethyl-2-bicyclo[3.1.1]heptanyl]ethyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	23.6 [1]
	(2S,3R)-3-Amino-1-[4-[(1R,5S)-9-[(1S,6R)-8-bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	1.98 [1]
	(2S,3R)-1-[4-[(1R,5S)-9-[(1S,6R)-8-Bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]-3-(dimethylamino)azetidine-2-carboxylic acid	Ki	1.97 [1]
	(2S)-1-[4-[(1R,5S)-9-[(1S,5R)-3-Bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]pyrrolidine-2-carboxylic acid	Ki	98.0 [1]
	(2S)-1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]pyrrolidine-2-carboxylic acid	Ki	15.0 [1]
	2-[1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxalin-2-yl]azetidin-3-yl]acetic acid	Ki	264.0 [1]
	(2S)-1-[4-[(1S,5R)-9-[(1R,5S)-3-Bicyclo[3.3.2]decanyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxalin-2-yl]pyrrolidine-2-carboxylic acid	Ki	511.0 [1]
	2-[1-[4-[(1R,5S)-9-[(1S,6R)-8-Bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidin-3-yl]acetic acid	Ki	1.32 [1]
	(2S)-1-[4-[(1R,5S)-9-[(1S,3S,5R,7S)-9-Methyl-5-tricyclo[5.2.1.03,9]decanyl]-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxalin-2-yl]pyrrolidine-2-carboxylic acid	Ki	272.0 [1]
	(2R)-1-[4-[(1S,5R)-9-[2-[(1S,2S,5S)-6,6-Dimethyl-2-bicyclo[3.1.1]heptanyl]ethyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	80.0 [1]
	(2S,3R)-3-Acetamido-1-[4-[(1R,5S)-9-[(1S,5R)-3-bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	39.9 [1]
	(2S,3R)-3-Acetamido-1-[4-[(1R,5S)-9-[(1S,6R)-8-bicyclo[4.3.1]decanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxalin-2-yl]azetidine-2-carboxylic acid	Ki	3.14 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-16-[[4-(1,1-difluoroethyl)phenyl]methoxymethyl]-11,15-dimethoxy-5-methyl-13-oxa-5-azoniahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	20000.0 [1]
	N,N,3,6-Tetramethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	4.4 [1]
	1'-(4-Fluorophenyl)-N,N-dimethylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	3.2 [1]
	7-Fluoro-N,N-dimethyl-1'-phenylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	6.9 [1]
	1-[1'-(Dimethylamino)-1'-phenylspiro[4,9-dihydro-3H-pyrido[3,4-b]indole-1,4'-cyclohexane]-2-yl]ethanone	Ki	2.4 [1]
	1'-(3-Fluorophenyl)-N,N-dimethylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	1.2 [1]
	N,N-Dimethyl-1'-phenylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	3.4 [1]
	N,N,3-Trimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	42.0 [1]
	N,N-Dimethyl-1'-phenylspiro[4,9-dihydro-3H-thiopyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	3.7 [1]
	N,N,3-Trimethyl-6-nitro-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	29.0 [1]
	N,N,3-Trimethyl-1'-phenylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	0.5 [1]
	6-Fluoro-N,N,3-trimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	83.0 [1]
	1'-(Dimethylamino)-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-6-ol	Ki	1.6 [1]
	1'-Benzyl-N,N-dimethylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	1.1 [1]
	6-Fluoro-N,N-dimethyl-1'-phenylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	1.4 [1]
	N,N,6-Trimethyl-1'-phenylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	32.0 [1]
	6-Bromo-N,N,3-trimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	23.0 [1]
	6-Bromo-N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	52.0 [1]
	6-Methoxy-N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	5.8 [1]
	Lexanopadol	Ki	10.0 [1]
	N-Methyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	1.4 [1]
	2-[[(3S)-1-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]pyrrolidin-3-yl]amino]acetic acid	Ki	500.0 [1]
	3-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)-1-(1-cyclooctylpiperidin-4-yl)quinoxalin-2-one	Ki	52.8 [1]
	1-[4-[3-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)-2-oxoquinoxalin-1-yl]piperidin-1-yl]cyclooctane-1-carboxamide	Ki	44.6 [1]
	N,N,6-Trimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine	Ki	4.5 [1]
	1'-(4-Fluorophenyl)-N,N-dimethyl-2-oxospiro[3,4-dihydrothiopyrano[3,4-b][1]benzothiole-1,4'-cyclohexane]-1'-amine	Ki	62.0 [1]
	Methyl 1'-(dimethylamino)-1'-phenylspiro[2,3,4,9-tetrahydropyrido[3,4-b]indole-1,4'-cyclohexane]-3-carboxylate	Ki	0.9 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-11,15-dimethoxy-16-[[4-(trifluoromethyl)phenyl]methoxymethyl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	3957.55 [1]
	(1S,2S,6R,14R,15R,16R)-16-(Cyclohexylmethoxymethyl)-11,15-dimethoxy-5-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	1034.67 [1]
	(1S,2S,6R,14R,15R,16R)-11,15-Dimethoxy-5-methyl-16-[[4-(trifluoromethyl)phenyl]methoxymethyl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	13803.96 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-16-[(3,4-dichlorophenyl)methoxymethyl]-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	823.29 [1]
	(2S,6R)-11,15-Dimethoxy-5-methyl-16-(phenylmethoxymethyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	569.0 [1]
	(2S,6R)-11,15-Dimethoxy-5-methyl-16-(prop-2-enoxymethyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	1295.55 [1]
	(1S,2S,6R,14R,15R,16R)-16-[(4-Tert-butylphenyl)methoxymethyl]-11,15-dimethoxy-5-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	4555.05 [1]
	(1S,2S,6R,14R,15R,16R)-11,15-Dimethoxy-5-methyl-16-(phenoxymethyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	2571.83 [1]
	(1S,2S,6R,14R,15R,16R)-16-(Cyclohexylmethoxymethyl)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	1165.91 [1]
	(1S,2S,6R,14R,15R,16R)-11,15-Dimethoxy-5-methyl-16-[(3-methylphenyl)methoxymethyl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	1602.42 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-11,15-dimethoxy-16-[(4-phenylphenyl)methoxymethyl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	20000.0 [1]
	(1S,2S,6R,14R,15R,16R)-16-[(4-Chlorophenyl)methoxymethyl]-11,15-dimethoxy-5-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	1116.98 [1]
	(1S,2S,6R,14R,15R,16R)-5-(Cyclopropylmethyl)-11,15-dimethoxy-16-(phenoxymethyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	9605.7 [1]
	(1S,2S,6R,14R,15R,16R)-11,15-Dimethoxy-5-methyl-16-(naphthalen-2-ylmethoxymethyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene	Ki	20000.0 [1]
	4-[(1R,5S)-9-Cyclodecyl-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	1.8 [1]
	4-[(1R,5S)-9-[(1S,5R)-7-Methyl-3-bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	1.1 [1]
	4-[(1R,5S)-8-(9-Bicyclo[3.3.1]nonanyl)-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	4.8 [1]
	4-[(1R,5S)-8-Cyclononyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	2.0 [1]
	4-[(1R,5S)-9-Cyclononyl-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	1.4 [1]
	4-[(1R,5S)-8-Cyclodecyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	2.5 [1]
	4-[(1R,5S)-9-(1-Bicyclo[3.3.1]nonanyl)-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Ki	30.2 [1]
	4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxo-N-(2H-tetrazol-5-ylmethyl)quinoxaline-2-carboxamide	Ki	157.0 [1]
	4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-N-hydroxy-3-oxoquinoxaline-2-carboxamide	Ki	2.7 [1]
	2-[2-[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-2-oxoacetic acid	Ki	71.4 [1]
	3-(5-Acetyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl)-1-(1-cyclooctylpiperidin-4-yl)quinoxalin-2-one	Ki	96.5 [1]
	(1S,3R)-3-[[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]amino]cyclopentane-1-carboxylic acid	Ki	607.4 [1]
	4-[[[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]amino]methyl]benzoic acid	Ki	456.0 [1]
	3-[(3S)-3-Aminopyrrolidin-1-yl]-1-(1-cyclooctylpiperidin-4-yl)quinoxalin-2-one	Ki	4.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Opioid growth factor receptor-like protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/opioid-growth-factor-receptor-like-protein-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Opioid growth factor receptor-like protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/opioid-growth-factor-receptor-like-protein-1-inhibitors-ic50-ki.
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