Name: Orexin receptor 1 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Orexin receptor 1 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Suvorexant	IC50	50.0 ^[1], 199.0 ^[2]
	Suvorexant	Ki	0.55 ^[1], 0.6 ^[2]
	[5-Methyl-2-(triazol-2-yl)phenyl]-(4-quinazolin-2-yl-1,4-diazepan-1-yl)methanone	IC50	29.0 ^[1]
	[5-Methyl-2-(triazol-2-yl)phenyl]-(4-quinazolin-2-yl-1,4-diazepan-1-yl)methanone	Ki	1.2 ^[1]
	Filorexant	IC50	11.0 ^[1], 16.0 ^[2]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Orexin receptor 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 15 Dec. 2025, https://www.aatbio.com/data-sets/orexin-receptor-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 15). Quest Database™ Orexin receptor 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/orexin-receptor-1-inhibitors-ic50-ki.
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