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Oxoeicosanoid receptor 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
3-Methyl-5-oxo-5-(2-hexyl-6-chloro-1H-indole-1-yl)pentanoic acidIC5018.0 [1]
3-Methyl-5-oxo-5-(1-methyl-2-hexyl-5-chloro-1H-indole-3-yl)pentanoic acidIC5016.0 [1], 17.0 [2], 28.0 [3], 33.0 [4], 454.0 [5]
(3S)-5-(5-Chloro-2-hexyl-1-methylindol-3-yl)-3-methyl-5-oxopentanoic acidIC506.0 [1]
5-Indol-1-yl-5-oxopentanoic acidIC5030000.0 [1]
(3R)-5-(5-Chloro-2-hexyl-1-methylindol-3-yl)-3-methyl-5-oxopentanoic acidIC502.7 [1], 2700.0 [2]
5-(2-Hexyl-indol-1-yl)-5-oxo-pentanoic acidIC501130.0 [1], 1550.0 [2]
Docosahexaenoic acidIC502000.0 [1]
Eicosapentaenoic acidIC502000.0 [1]
Dihomo-gamma-linolenic acidIC502000.0 [1]
5-Oxo-ETEIC503.0 [1]
11,14,17-Eicosatrienoic acidIC502000.0 [1]
12(S)-HeteIC50500.0 [1]
5-Oxo-12-HETEIC50500.0 [1]
5-(7-Hexylindol-1-yl)-5-oxopentanoic acidIC5011770.0 [1]
5-(5-Hexylindol-1-yl)-5-oxopentanoic acidIC5017670.0 [1]
5-(6-Hexylindol-1-yl)-5-oxopentanoic acidIC5018000.0 [1]
5-(3-Hexylindol-1-yl)-5-oxopentanoic acidIC5020680.0 [1]
(6E,8E,10E,12S,14Z)-12-Hydroxy-5-oxoicosa-6,8,10,14-tetraenoic acidIC502500.0 [1]
5-[6-Chloro-2-[(E)-hex-1-enyl]indol-1-yl]-3-methyl-5-oxopentanoic acidIC5018500.0 [1]
5-[6-Chloro-2-[(Z)-hex-1-enyl]indol-1-yl]-3-methyl-5-oxopentanoic acidIC50460.0 [1]
5-[5-Chloro-1-methyl-2-(5-phenylpentyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC5011.0 [1]
5-[5-Chloro-1-methyl-2-(6-phenylhexyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC500.28 [1]
5-[5-Chloro-1-methyl-2-(3-phenylpropyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC50223.0 [1]
(3S)-5-[5-Chloro-1-methyl-2-(6-phenylhexyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC500.12 [1]
5-[5-Chloro-1-methyl-2-(4-phenylbutyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC5038.0 [1]
(3R)-5-[5-Chloro-1-methyl-2-(6-phenylhexyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC5023.0 [1]
5-(5-Chloro-2-hexyl-1-methylindol-3-yl)-3,3-dimethyl-5-oxopentanoic acidIC501330.0 [1]
5-(5-Chloro-2-hexyl-1-methylindol-3-yl)-4,4-dimethyl-5-oxopentanoic acidIC508150.0 [1]
4-(5-Chloro-2-hexyl-1-methylindole-3-carbonyl)benzoic acidIC501360.0 [1]
2-[1-[2-(5-Chloro-2-hexyl-1-methylindol-3-yl)-2-oxoethyl]cyclopropyl]acetic acidIC50580.0 [1]
5-(5-Chloro-1-methyl-2-undecylindol-3-yl)-3-methyl-5-oxopentanoic acidIC5023.0 [1]
2-[1-[2-(5-Chloro-2-hexyl-1-methylindol-3-yl)-2-oxoethyl]cyclobutyl]acetic acidIC50720.0 [1]
2-[2-(5-Chloro-2-hexyl-1-methylindol-3-yl)-2-oxoethoxy]acetic acidIC505500.0 [1]
5-(5-Chloro-2-hexyl-1-methylindol-3-yl)-2,2-dimethyl-5-oxopentanoic acidIC504060.0 [1]
5-[6-Chloro-2-(3-phenylpropyl)indol-1-yl]-3-methyl-5-oxopentanoic acidIC50210.0 [1]
5-[6-Chloro-2-(5-phenylpentyl)indol-1-yl]-3-methyl-5-oxopentanoic acidIC502.1 [1]
(3S)-5-[5-Chloro-2-[(1S)-1-hydroxy-6-phenylhexyl]-1-methylindol-3-yl]-3-methyl-5-oxopentanoic acidIC500.38 [1]
5-[5-Chloro-1-methyl-2-(6,6,6-trifluorohexyl)indol-3-yl]-3-methyl-5-oxopentanoic acidIC5038.0 [1]
(3R)-5-[5-Chloro-2-[(1S)-1-hydroxy-6-phenylhexyl]-1-methylindol-3-yl]-3-methyl-5-oxopentanoic acidIC50120.0 [1]
5-[6-Chloro-2-(6-phenylhexyl)indol-1-yl]-3-methyl-5-oxopentanoic acidIC5012.0 [1]
5-[6-Chloro-2-(4-phenylbutyl)indol-1-yl]-3-methyl-5-oxopentanoic acidIC5018.0 [1]
(3R)-5-[5-Chloro-2-[(1R)-1-hydroxy-6-phenylhexyl]-1-methylindol-3-yl]-3-methyl-5-oxopentanoic acidIC50750.0 [1]
(3S)-5-[5-Chloro-2-[(1R)-1-hydroxy-6-phenylhexyl]-1-methylindol-3-yl]-3-methyl-5-oxopentanoic acidIC50260.0 [1]
5-Oxo-5-(2-pentylindol-1-yl)pentanoic acidIC502150.0 [1]
5-(2-Hexylindol-1-yl)-3,3-dimethyl-5-oxopentanoic acidIC5011000.0 [1]
5-Oxo-5-(2-undecyl-indol-1-yl)-pentanoic acidIC50700.0 [1]
5-(2-Octylindol-1-yl)-5-oxopentanoic acidIC50570.0 [1]
5-(2-Butylindol-1-yl)-5-oxopentanoic acidIC5013700.0 [1]
5-(2-Heptylindol-1-yl)-5-oxopentanoic acidIC50750.0 [1]
2-[1-[2-(2-Hexylindol-1-yl)-2-oxoethyl]cyclopropyl]acetic acidIC501630.0 [1]
5-(5-Chloro-2-hexyl-1-methylindol-3-yl)-5-oxopentanoic acidIC50566.0 [1]
5-(2-Hexyl-quinolin-3-yl)-5-oxo-pentanoic acidIC5030000.0 [1]
(3S)-5-(6-Chloro-2-hexylindol-1-yl)-3-methyl-5-oxopentanoic acidIC502.2 [1]
3-(5-Chloro-2-hexyl-1-methylindole-3-carbonyl)benzoic acidIC501120.0 [1]
3-Methyl-5-oxo-5-(1-methyl-2-hexyl-6-chloro-1H-indole-3-yl)pentanoic acidIC5081.0 [1]
5-(2-Hexyl-indol-1-yl)-3-methyl-5-oxo-pentanoic acidIC5090.0 [1]
5-(2-Hexyl-1-methyl-1H-indol-3-yl)-5-oxo-pentanoic acidIC506060.0 [1]
3-Methyl-5-oxo-5-(1-methyl-2-hexyl-1H-indole-3-yl)pentanoic acidIC50314.0 [1]
CID 53248990IC507.5 [1]
3-Methyl-5-oxo-5-(2-hexyl-5-chloro-1H-indole-1-yl)pentanoic acidIC50141.0 [1]
5-[2-[(E)-Hex-1-enyl]indol-1-yl]-5-oxopentanoic acidIC504030.0 [1]
5-Oxo-5-[2-[(Z)-undec-1-enyl]indol-1-yl]pentanoic acidIC50550.0 [1]
4-(2-Hexylindol-1-yl)-4-oxobutanoic acidIC5030000.0 [1]
5-(5-Chloroindol-1-yl)-5-oxopentanoic acidIC501170.0 [1]
5-(6-Chloroindol-1-yl)-5-oxopentanoic acidIC50400.0 [1]
5-(5-Bromo-2-hexyl-1-methylindol-3-yl)-3-methyl-5-oxopentanoic acidIC5026.0 [1]
5-(6-Bromo-2-hexylindol-1-yl)-3-methyl-5-oxopentanoic acidIC5030.0 [1]
5-(2-Hexyl-6-methoxyindol-1-yl)-3-methyl-5-oxopentanoic acidIC50323.0 [1]
3-Methyl-5-oxo-5-(2-hexyl-3-methyl-1H-indole-1-yl)pentanoic acidIC50136.0 [1]
5-(5-Bromo-2-hexylindol-1-yl)-3-methyl-5-oxopentanoic acidIC50638.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Oxoeicosanoid receptor 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.10 May2024https://www.aatbio.com/data-sets/oxoeicosanoid-receptor-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024May 10). Quest Database™ Oxoeicosanoid receptor 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/oxoeicosanoid-receptor-1-inhibitors-ic50-ki.
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