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P2X purinoceptor 4 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
CID 9841560IC50350.0 [1], 500.0 [2]
ParoxetineIC501870.0 [1], 4680.0 [2]
Benzyl 10H-phenoxazine-10-carboxylateIC50189.0 [1]
CarbamazepineIC50100000.0 [1]
OxcarbazepineIC5010000.0 [1]
PpadsIC5027500.0 [1]
Carbamazepine-10,11-epoxideIC5010000.0 [1]
Eslicarbazepine acetateIC5020000.0 [1]
Hexasodium;8-[[3-[[3-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoylamino]benzoyl]amino]naphthalene-1,3,5-trisulfonateIC50100000.0 [1]
LicarbazepineIC50100000.0 [1]
10,11-DihydrocarbamazepineIC50100000.0 [1]
9-ChloroacridineIC5010000.0 [1]
2,4-Pyrimidinediamine, 5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-IC5010000.0 [1]
CID 24883277IC5010000.0 [1]
10-Tosyl-10H-phenoxazineIC501380.0 [1]
5-Ethoxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
Dibenzo[b,f]azepine-5-carboxylic acid methyl esterIC50100000.0 [1]
N,N-Diethyl-5H-dibenzo[b,f]azepine-5-carboxamideIC5011400.0 [1]
Dibenzo[b,f]azepine-5-carboxylic acid methylamideIC50100000.0 [1]
2-HydroxycarbamazepineIC50146000.0 [1]
5-Acetyl-5H-dibenz[b,f]azepineIC50100000.0 [1]
CID 11636757IC501000.0 [1]
3-HydroxycarbamazepineIC5072800.0 [1]
9(10H)-Acridinone, 10-(phenylmethyl)-IC505970.0 [1]
N-(2-Hydroxyphenyl)benzamideIC5010000.0 [1]
2,3-Dihydro-1,4-benzoxazin-4-yl(phenyl)methanoneIC5010000.0 [1]
[(3Ar,4R,6R,6aR)-4-(6-aminopurin-9-yl)-6-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]-3',5'-dinitrospiro[3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-2,4'-cyclohexa-2,5-diene]-1'-ylidene]-dioxidoazaniumIC5015200.0 [1]
Benzo[b][1]benzazepin-11-yl(piperidin-1-yl)methanoneIC5013700.0 [1]
Benzo[b][1]benzazepin-11-yl(pyrrolidin-1-yl)methanoneIC5034100.0 [1]
10-MethoxycarbamazepineIC50100000.0 [1]
11-Benzylbenzo[b][1]benzazepineIC50100000.0 [1]
N-AcetylphenoxazineIC5010000.0 [1]
10-[(4-Methoxyphenyl)methyl]acridin-9-oneIC5010300.0 [1]
2-FluorocarbamazepineIC50100000.0 [1]
10-[(4-Nitrophenyl)methyl]acridin-9-oneIC502490.0 [1]
10-Benzoylacridin-9-oneIC5026900.0 [1]
N-(2-Hydroxyphenyl)morpholine-4-carboxamideIC5010000.0 [1]
Phenoxazine-10-carbonyl chlorideIC5023200.0 [1]
(4-Nitrophenyl)-phenoxazin-10-ylmethanoneIC504290.0 [1]
(4E)-5-Cyclohexyl-4-[hydroxy-(4-methoxyphenyl)methylidene]-1-[4-(1,2-oxazol-3-yl)phenyl]pyrrolidine-2,3-dioneIC5030000.0 [1]
Benzyl(2-Hydroxyphenyl)CarbamateIC5010000.0 [1]
Phenoxazin-10-yl(phenyl)methanoneIC504110.0 [1]
N-[3-(Dimethylamino)propyl]benzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
N-[2-[2-(2-Benzamidophenoxy)ethoxy]phenyl]benzamideIC5010000.0 [1]
N-Phenylbenzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
N-[(2R)-1-(4-Acetylpiperazin-1-yl)propan-2-yl]-1-methyl-3-phenylthieno[2,3-c]pyrazole-5-carboxamideIC5010000.0 [1]
2-Phenyl-4-propyl-N-[1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-yl]-1,3-oxazole-5-carboxamideIC5010000.0 [1]
(4S)-N-[4-Chloro-5-(2-hydroxyethoxy)-2-methylphenyl]-4-(4-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyridine-5-carboxamideIC5010000.0 [1]
5-Benzoyl-5H-dibenz[b,f]azepinIC5023300.0 [1]
2-Methylbenzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
5-Aminobenzo[b][1]benzazepine-11-carboxamideIC5010000.0 [1]
2-Methoxybenzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
10-Benzyl-10H-phenoxazineIC5010000.0 [1]
(4-Methylphenyl)methyl phenoxazine-10-carboxylateIC502280.0 [1]
(4-Methoxyphenyl)methyl phenoxazine-10-carboxylateIC502640.0 [1]
N-Propan-2-ylphenoxazine-10-carboxamideIC5010000.0 [1]
Phenoxazin-10-yl(piperidin-1-yl)methanoneIC5010700.0 [1]
Methyl phenoxazine-10-carboxylateIC5052300.0 [1]
Benzyl 2H-benzo[b][1,4]oxazine-4(3H)-carboxylateIC5010000.0 [1]
1-Phenoxazin-10-yl-2-phenylethanoneIC5010000.0 [1]
N-[3-(Dimethylamino)propyl]phenoxazine-10-carboxamideIC5010000.0 [1]
10-BenzylsulfonylphenoxazineIC5010000.0 [1]
N-Methylphenoxazine-10-carboxamideIC5010000.0 [1]
N-Benzylphenoxazine-10-carboxamideIC5010000.0 [1]
2-Phenylethyl phenoxazine-10-carboxylateIC503930.0 [1]
S-(2-Phenylethyl) phenoxazine-10-carbothioateIC5010000.0 [1]
N,N-Diethyl-9-oxoacridine-10-carboxamideIC5039100.0 [1]
N-(2-Hydroxyphenyl)-2-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxyacetamideIC503390.0 [1]
N-Cyclohexylphenoxazine-10-carboxamideIC5010000.0 [1]
N,N-Diethylphenoxazine-10-carboxamideIC5017400.0 [1]
(4-Nitrophenyl)methyl phenoxazine-10-carboxylateIC5010000.0 [1]
N-[2-(2-Bromoethoxy)phenyl]-2-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxyacetamideIC5010000.0 [1]
N-(2-Phenylethyl)phenoxazine-10-carboxamideIC501780.0 [1]
N,N-Di(propan-2-yl)phenoxazine-10-carboxamideIC5012400.0 [1]
(4-Chlorophenyl)-phenoxazin-10-ylmethanoneIC505290.0 [1]
9-Phenyl-10-benzyl-9,10-dihydroacridine-9-olIC502440.0 [1]
2,3-Dihydro-1,4-benzoxazin-4-yl(morpholin-4-yl)methanoneIC5010000.0 [1]
Phenoxazine-10-carboxamideIC5010000.0 [1]
N-(1-Methylpiperidin-4-yl)phenoxazine-10-carboxamideIC5045800.0 [1]
N,N-Dipropylphenoxazine-10-carboxamideIC502690.0 [1]
Morpholin-4-yl(phenoxazin-10-yl)methanoneIC5010000.0 [1]
10-[(4-Methylphenyl)methyl]acridin-9-oneIC5011800.0 [1]
N-[(3,5-Dichlorophenyl)methyl]phenoxazine-10-carboxamideIC5010000.0 [1]
N,N-Dimethylphenoxazine-10-carboxamideIC5024600.0 [1]
Propan-2-yl phenoxazine-10-carboxylateIC502350.0 [1]
(4-Chlorophenyl)methyl phenoxazine-10-carboxylateIC501020.0 [1]
(4-Aminophenyl)-phenoxazin-10-ylmethanoneIC5010800.0 [1]
N-[(4-Chlorophenyl)methyl]phenoxazine-10-carboxamideIC509540.0 [1]
(4-Methylpiperazin-1-yl)-phenoxazin-10-ylmethanoneIC5010000.0 [1]
N,N-Di(propan-2-yl)benzo[b][1]benzazepine-11-carboxamideIC503440.0 [1]
N-[2-(Dimethylamino)ethyl]-N-methylbenzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
N-(4-Aminocyclohexyl)benzo[b][1]benzazepine-11-carboxamideIC5010000.0 [1]
Benzyl benzo[b][1]benzazepine-11-carboxylateIC506020.0 [1]
11-N,11-N-Diethyl-1-N,1-N-di(propan-2-yl)benzo[b][1]benzazepine-1,11-dicarboxamideIC5052500.0 [1]
2-Methylpropyl benzo[b][1]benzazepine-11-carboxylateIC50100000.0 [1]
N-Tert-butylbenzo[b][1]benzazepine-11-carboxamideIC5013800.0 [1]
N-(4-Hydroxycyclohexyl)benzo[b][1]benzazepine-11-carboxamideIC5020000.0 [1]
2-(Dimethylamino)benzo[b][1]benzazepine-11-carboxamideIC5015300.0 [1]
N-[2-(4-Methoxyphenyl)ethyl]benzo[b][1]benzazepine-11-carboxamideIC5027400.0 [1]
N-Butylbenzo[b][1]benzazepine-11-carboxamideIC50100000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ P2X purinoceptor 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/p2x-purinoceptor-4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ P2X purinoceptor 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/p2x-purinoceptor-4-inhibitors-ic50-ki.
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