Name: p53-binding protein Mdm-2 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

p53-binding protein Mdm-2 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Nutlin-3A	IC50	90.0 ^[1]
	Nutlin-3A	Ki	6.4 ^[1], 40.0 ^[2], 90.0 ^[3], 121.0 ^[4], 140.0 ^[5]
	2-[(3R,5R,6S)-1-[(1S)-2-Tert-butylsulfonyl-1-cyclopropylethyl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetic acid	IC50	0.1 ^[1]
	MI-773 (Sar405838)	IC50	13.3 ^[1], 100.0 ^[2]
	MI-773 (Sar405838)	Ki	0.88 ^[1], 10.0 ^[2]
Rows per page: 1–5 of 100

References

This online resource may be cited as follows

MLA	"Quest Database™ p53-binding protein Mdm-2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 5 Dec. 2025, https://www.aatbio.com/data-sets/p53-binding-protein-mdm-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, December 5). Quest Database™ p53-binding protein Mdm-2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/p53-binding-protein-mdm-2-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan