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Pancreatic lipase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
▲
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Standard Values (in nM)
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▼
OrlistatIC50190.0 [1]
Carnosic acidIC5036000.0 [1]
CarnosolIC5013000.0 [1]
MahanimbineIC5017900.0 [1]
KoenimbineIC50168600.0 [1]
KoenigicineIC50428600.0 [1]
(S)-4-Isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-oneIC5050000.0 [1]
N-Methyl-5-methylsulfanyl-N-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,2,4-triazole-1-carboxamideIC5050000.0 [1]
3-(4-Chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trifluoroethylsulfanyl)-1,2,4-triazole-1-carboxamideIC5050000.0 [1]
4-Tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazol-3-yl)-phenyl]-benzamideIC5010000.0 [1]
Ostalactone BIC503200.0 [1]
Ostalactone AIC509000.0 [1]
3-(3-(Benzyloxy)phenyl)-5-ethoxy-1,3,4-oxadiazol-2(3H)-oneIC5010000.0 [1]
[1-[(2-Phenylphenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC5013480.0 [1]
[1-[(4-Fluorophenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC501100.0 [1]
[1-[(2-Bromo-5-methoxyphenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC506900.0 [1]
(E)-5-[(4As,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoic acidIC5011750.0 [1]
[1-[(4-Methoxyphenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC501870.0 [1]
(1-Benzyltriazol-4-yl)methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC509150.0 [1]
[1-[(4-Tert-butylphenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC502280.0 [1]
(1-Phenacyltriazol-4-yl)methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC507820.0 [1]
[1-[(2-Bromo-4-fluorophenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC502310.0 [1]
(2E)-2-[2-[(4As,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]butanedialIC5014480.0 [1]
[1-[(4-Methylsulfanylphenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC501650.0 [1]
[1-[(4-Chlorophenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC501250.0 [1]
[1-[(4-Nitrophenyl)methyl]triazol-4-yl]methyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC502010.0 [1]
Prop-2-ynyl (E)-5-[(4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-formylpent-3-enoateIC507380.0 [1]
Methyl (2R)-2-[[(2E,8E)-deca-2,8-dienoyl]amino]-3-[(5R)-5-hydroxy-6-oxo-3,8-dioxatricyclo[5.1.0.02,4]octan-5-yl]propanoateIC50270000.0 [1]
Methyl (2S)-2-[[(2E,8E)-deca-2,8-dienoyl]amino]-3-[(5S)-5-hydroxy-6-oxo-3,8-dioxatricyclo[5.1.0.02,4]octan-5-yl]propanoateIC5027000.0 [1]
(2S)-2-[[(2R,3R)-2-[[(2R)-5-Amino-2-[[2-[[(2R)-1-[(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-sulfanylpropanoic acidIC5016000.0 [1]
N'-[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-N-(4-heptoxyphenyl)butanediamideKi67000.0 [1]
N'-[(2S)-1-[[(2S)-1-Amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-N-(4-butoxyphenyl)butanediamideKi550000.0 [1]
N'-[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-N-(4-butoxyphenyl)butanediamideKi170000.0 [1]
N'-[(1S)-2-[[(1S)-2-Amino-1-naphthalen-2-yl-2-oxoethyl]amino]-1-naphthalen-2-yl-2-oxoethyl]-N-(4-butoxyphenyl)butanediamideKi360000.0 [1]
Methyl 2-[[(2E,8E)-deca-2,8-dienoyl]amino]-3-(5-hydroxy-6-oxo-3,8-dioxatricyclo[5.1.0.02,4]octan-5-yl)propanoateIC50120000.0 [1]
Items per page: 1 - 10 of 35
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References

This online tool may be cited as follows

MLA

"Quest Database™ Pancreatic lipase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/pancreatic-lipase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Pancreatic lipase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/pancreatic-lipase-inhibitors-ic50-ki.
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