Peptidyl-prolyl cis-trans isomerase D Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Cyclosporin A	IC50	3.6 [1]
	Cyclosporin A	Ki	2.58 [1], 7.0 [2], 8.2 [3], 34.0 [4]
	Ethyl N-[(4-Aminobenzyl)carbamoyl]glycinate	IC50	6200.0 [1]
	Ethyl N-[(4-Aminobenzyl)carbamoyl]glycinate	Ki	2900.0 [1], 5900.0 [2]
	2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-N-(4-sulfamoylphenyl)-1,3-thiazole-5-carboxamide	IC50	1490.0 [1]
	2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-N-(4-sulfamoylphenyl)-1,3-thiazole-5-carboxamide	Ki	1330.0 [1]
	Ethyl N-{[3-(3-Aminopyridin-4-Yl)benzyl]carbamoyl}glycinate	Ki	22000.0 [1]
	Ethyl N-[(4-Aminobenzyl)carbamoyl]-L-Methioninate	Ki	9100.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[(2S)-4-methylsulfanyl-1-[(2S)-2-(2-methylsulfanylphenyl)pyrrolidin-1-yl]-1-oxobutan-2-yl]urea	Ki	99.0 [1]
	Ethyl N-(Benzylcarbamoyl)glycinate	Ki	63000.0 [1]
	1-(4-Aminobenzyl)-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea	Ki	4900.0 [1]
	5-[[4-[(E,4R,5R)-5-[(2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-Ethyl-1,7,10,16,20,23,25,28,31-nonamethyl-11,17,26,29-tetrakis(2-methylpropyl)-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-14,32-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacont-2-yl]-5-hydroxy-4-methylpent-1-enyl]phenyl]methylcarbamoyl]-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid	Ki	12.0 [1]
	1-(4-Aminobenzyl)-3-{2-[(2r)-2-(2-Bromophenyl)pyrrolidin-1-Yl]-2-Oxoethyl}urea	Ki	950.0 [1]
	Ethyl N-{[4-(Acetylamino)benzyl]carbamoyl}glycinate	Ki	2600.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[2-[2-(2-methylsulfanylphenyl)pyrrolidin-1-yl]-2-oxoethyl]urea	IC50	640.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[4-methylsulfanyl-1-[2-(2-methylsulfanylphenyl)pyrrolidin-1-yl]-1-oxobutan-2-yl]urea	IC50	660.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[4-methyl-1-[2-(2-methylsulfanylphenyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]urea	IC50	3000.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[1-[2-(2-methylsulfanylphenyl)pyrrolidin-1-yl]-1-oxopropan-2-yl]urea	IC50	1100.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[2-[2-(2-bromophenyl)pyrrolidin-1-yl]-2-oxoethyl]urea	IC50	1100.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[2-[2-(2-chlorophenyl)pyrrolidin-1-yl]-2-oxoethyl]urea	IC50	6200.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[2-[2-(2-methoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl]urea	IC50	11400.0 [1]
	1-[(4-Aminophenyl)methyl]-3-[2-(2-naphthalen-1-ylpyrrolidin-1-yl)-2-oxoethyl]urea	IC50	1400.0 [1]
	2-[(4-Aminophenyl)methylcarbamoylamino]-N-ethyl-N-phenylmethoxyacetamide	IC50	30000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 23 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Peptidyl-prolyl cis-trans isomerase D Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/peptidyl-prolyl-cis-trans-isomerase-d-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Peptidyl-prolyl cis-trans isomerase D Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/peptidyl-prolyl-cis-trans-isomerase-d-inhibitors-ic50-ki.
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