Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Juglone	IC50	5900.0 [1], 10030.0 [2], 10120.0 [3], 10810.0 [4]
	Cyclic crypeveic	IC50	500.0 [1]
	Cyclic crypeveic	Ki	200.0 [1], 520.0 [2]
	[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-(3-fluorophenyl)propyl] dihydrogen phosphate	IC50	6.0 [1], 50.0 [2]
	[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-(3-fluorophenyl)propyl] dihydrogen phosphate	Ki	6.0 [1]
	Acetyl-11-keto-beta-boswellic acid	IC50	50360.0 [1], 52990.0 [2]
	Procodazole	IC50	10000.0 [1], 740000.0 [2]
	1,7-Diphenylheptan-4-yl (2S)-1-[[(2R)-1-phenyl-3-phosphonooxypropan-2-yl]carbamoyl]piperidine-2-carboxylate	IC50	800.0 [1]
	1,7-Diphenylheptan-4-yl (2S)-1-[[(2R)-1-phenyl-3-phosphonooxypropan-2-yl]carbamoyl]piperidine-2-carboxylate	Ki	800.0 [1]
	[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-phenylpropyl] dihydrogen phosphate	IC50	180.0 [1]
	[(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-phenylpropyl] dihydrogen phosphate	Ki	179.0 [1]
	(2R)-3-(6-Fluoro-1H-indol-2-yl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	2960.0 [1]
	(2R)-3-(6-Fluoro-1H-indol-2-yl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	138.0 [1]
	3-Fluoro-N-(naphthalen-2-ylcarbonyl)-D-phenylalanine	IC50	12000.0 [1]
	3-Fluoro-N-(naphthalen-2-ylcarbonyl)-D-phenylalanine	Ki	12000.0 [1]
	Piperidine-1-dithiocarboxylic acid, anhydrosulphide	IC50	4000.0 [1]
	Piperidine-1-dithiocarboxylic acid, anhydrosulphide	Ki	50.0 [1]
	(2R,4E)-2-[(Naphthalen-2-ylcarbonyl)amino]-5-phenylpent-4-enoic acid	IC50	50000.0 [1]
	(2R,4E)-2-[(Naphthalen-2-ylcarbonyl)amino]-5-phenylpent-4-enoic acid	Ki	1800.0 [1]
	(3R)-4-(3-Fluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	IC50	50000.0 [1]
	(3R)-4-(3-Fluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	Ki	5700.0 [1]
	(2R)-3-(3-Methylphenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	50000.0 [1]
	(2R)-3-(3-Methylphenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	2800.0 [1]
	(3R)-4-(3-Methylphenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	IC50	50000.0 [1]
	(3R)-4-(3-Methylphenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	Ki	9700.0 [1]
	(2R)-3-(3-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	50000.0 [1]
	(2R)-3-(3-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	3200.0 [1]
	(3R)-4-(3-Cyanophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	IC50	50000.0 [1]
	(3R)-4-(3-Cyanophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	Ki	2300.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-3-[3-(trifluoromethyl)phenyl]propanoic acid	IC50	50000.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-3-[3-(trifluoromethyl)phenyl]propanoic acid	Ki	1800.0 [1]
	(3R)-3-(Naphthalene-2-carbonylamino)-4-[3-(trifluoromethyl)phenyl]butanoic acid	IC50	50000.0 [1]
	(3R)-3-(Naphthalene-2-carbonylamino)-4-[3-(trifluoromethyl)phenyl]butanoic acid	Ki	13000.0 [1]
	(2R)-3-(3-Chlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	50000.0 [1]
	(2R)-3-(3-Chlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	3400.0 [1]
	(3R)-4-(3-Chlorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	IC50	50000.0 [1]
	(3R)-4-(3-Chlorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	Ki	2000.0 [1]
	(2R)-3-(3,4-Difluorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	50000.0 [1]
	(2R)-3-(3,4-Difluorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	23000.0 [1]
	(3R)-4-(3,4-Difluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	IC50	50000.0 [1]
	(3R)-4-(3,4-Difluorophenyl)-3-(naphthalene-2-carbonylamino)butanoic acid	Ki	82000.0 [1]
	(2R)-3-(3,4-Dichlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	50000.0 [1]
	(2R)-3-(3,4-Dichlorophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	2200.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-3-(3,4,5-trifluorophenyl)propanoic acid	IC50	50000.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-3-(3,4,5-trifluorophenyl)propanoic acid	Ki	9000.0 [1]
	(2R)-3-(4-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	IC50	50000.0 [1]
	(2R)-3-(4-Cyanophenyl)-2-(naphthalene-2-carbonylamino)propanoic acid	Ki	3000.0 [1]
	(R)-N-(2-(4-Fluorophenyl)-1-(1H-tetrazol-5-yl)ethyl)-2-naphthamide	IC50	50000.0 [1]
	(R)-N-(2-(4-Fluorophenyl)-1-(1H-tetrazol-5-yl)ethyl)-2-naphthamide	Ki	4000.0 [1]
	N-[(1R)-1-(2H-Tetrazol-5-yl)-2-[4-(trifluoromethyl)phenyl]ethyl]naphthalene-2-carboxamide	IC50	50000.0 [1]
	N-[(1R)-1-(2H-Tetrazol-5-yl)-2-[4-(trifluoromethyl)phenyl]ethyl]naphthalene-2-carboxamide	Ki	8500.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-5-phenylpent-4-ynoic acid	IC50	50000.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-5-phenylpent-4-ynoic acid	Ki	12800.0 [1]
	(2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acid	IC50	50000.0 [1]
	(2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acid	Ki	1870.0 [1]
	(2R)-5-(2-Hydroxyphenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acid	IC50	50000.0 [1]
	(2R)-5-(2-Hydroxyphenyl)-2-(naphthalene-2-carbonylamino)pent-4-ynoic acid	Ki	4430.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-5-thiophen-2-ylpent-4-ynoic acid	IC50	50000.0 [1]
	(2R)-2-(Naphthalene-2-carbonylamino)-5-thiophen-2-ylpent-4-ynoic acid	Ki	7000.0 [1]
	(E,2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acid	IC50	50000.0 [1]
	(E,2R)-5-(3-Fluorophenyl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acid	Ki	890.0 [1]
	(R)-2-(Benzo[b]thiophene-2-carboxamido)-5-phenylpent-4-enoic acid	IC50	50000.0 [1]
	(R)-2-(Benzo[b]thiophene-2-carboxamido)-5-phenylpent-4-enoic acid	Ki	3700.0 [1]
	(E,2R)-5-(Cyclohexen-1-yl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acid	IC50	50000.0 [1]
	(E,2R)-5-(Cyclohexen-1-yl)-2-(naphthalene-2-carbonylamino)pent-4-enoic acid	Ki	2000.0 [1]
	Cycloheximide	Ki	200000.0 [1]
	Tretinoin	IC50	820.0 [1]
	(-)-Epigallocatechin gallate	IC50	20000.0 [1]
	Enoxolone	IC50	10000.0 [1]
	5-Pyridin-2-yl-1H-pyrazole-3-carboxylic acid	IC50	720000.0 [1]
	5-(2-Methoxyphenyl)-2-furoic acid	IC50	1000000.0 [1]
	5-Methyl-1H-indole-2-carboxylic acid	IC50	16000.0 [1]
	PPIase-Parvulin Inhibitor	IC50	1500.0 [1]
	6-Methyl-1H-indole-2-carboxylic acid	IC50	630000.0 [1]
	2-Phenyl-1H-imidazole-4-carboxylic acid	IC50	180000.0 [1]
	2-(3-Chloro-4-fluorophenyl)-3(2H)-isothiazolone	IC50	6100.0 [1]
	2-Chloro-N-cyclopentyl-5-nitropyrimidin-4-amine	IC50	100000.0 [1]
	Elemonic acid	IC50	13160.0 [1]
	2-Phenyl-1H-imidazole-4,5-dicarboxylic acid	IC50	1460.0 [1]
	[(2R)-2-[[(2S)-2-[[(2S)-2-Acetamidopropanoyl]amino]propanoyl]amino]-3-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropyl] dihydrogen phosphate	IC50	1000.0 [1]
	2-Chloro-4-cyclohexyloxy-5-nitropyrimidine	IC50	100000.0 [1]
	2-Chloro-4-cyclopentyloxy-5-nitropyrimidine	IC50	100000.0 [1]
	2-(2-Chloro-5-nitropyrimidin-4-yl)oxybenzonitrile	IC50	9050.0 [1]
	2-Chloro-4-naphthalen-1-yloxy-5-nitropyrimidine	IC50	22600.0 [1]
	2-Chloro-4-naphthalen-2-yloxy-5-nitropyrimidine	IC50	16550.0 [1]
	[(2R,3Z)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-[(2R)-2-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]cyclopentylidene]propyl] dihydrogen phosphate	IC50	1500.0 [1]
	2-Chloro-4-(3-methoxyphenoxy)-5-nitropyrimidine	IC50	5040.0 [1]
	2-Chloro-4-(2-fluorophenoxy)-5-nitropyrimidine	IC50	2520.0 [1]
	2-Chloro-4-(2-methoxyphenoxy)-5-nitropyrimidine	IC50	4030.0 [1]
	(2R)-2-[[2-(9H-Fluoren-9-yl)acetyl]amino]-3-(6-fluoro-1H-indol-2-yl)propanoic acid	Ki	12.0 [1]
	2-[2-(2,6-Dichlorophenyl)ethyl]-4-[(6-fluoro-1H-indol-2-yl)methyl]-5H-1,3-thiazole-4-carboxylic acid	Ki	196.0 [1]
	[(2R,3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-2-acetamidohexanoyl]amino]propanoyl]amino]propanoyl]amino]-3-thiophen-2-ylpropanoyl]amino]-4-[(2S)-2-[[(2S)-1-[[(2S)-1,5-diamino-1,5-dioxopentan-2-yl]amino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxobutan-2-yl] dihydrogen phosphate	IC50	22000.0 [1]
	(2R)-2-(1-Benzothiophene-2-carbonylamino)-3-(6-fluoro-1H-benzimidazol-2-yl)propanoic acid	Ki	76.0 [1]
	2-[(E)-2-(2,6-Dichlorophenyl)ethenyl]-4-[(6-fluoro-1H-indol-2-yl)methyl]-5H-1,3-thiazole-4-carboxylic acid	Ki	580.0 [1]
	[(2R,3R)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-2-acetamidohexanoyl]amino]propanoyl]amino]propanoyl]amino]-3-(1-benzothiophen-3-yl)propanoyl]amino]-4-[(2S)-2-[[(2S)-1-[[(2S)-1,5-diamino-1,5-dioxopentan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]carbamoyl]piperidin-1-yl]-4-oxobutan-2-yl] dihydrogen phosphate	Ki	1.2 [1]
	2-(9H-Fluoren-9-ylmethyl)-4-[(6-fluoro-1H-indol-2-yl)methyl]-5H-1,3-thiazole-4-carboxylic acid	Ki	320.0 [1]
	3-(6-Fluoro-1h-Benzimidazol-2-Yl)-N-(Naphthalen-2-Ylcarbonyl)-D-Alanine	Ki	80.0 [1]
	4-[(6-Fluoro-1H-indol-2-yl)methyl]-2-naphthalen-2-yl-5H-1,3-thiazole-4-carboxylic acid	Ki	1360.0 [1]
	(2R)-2-[3-(2,6-Dichlorophenyl)propanoylamino]-3-(6-fluoro-1H-indol-2-yl)propanoic acid	Ki	75.0 [1]
	[(2R)-3-(3-Methylphenyl)-2-(naphthalene-2-carbonylamino)propyl] dihydrogen phosphate	Ki	32.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/peptidyl-prolyl-cis-trans-isomerase-nima-interacting-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/peptidyl-prolyl-cis-trans-isomerase-nima-interacting-1-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan