Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Pictilisib	IC50	6039.0 [1], 10000.0 [2], 100000.0 [3]
	4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine	IC50	100000.0 [1]
	N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide	IC50	16000.0 [1]
	N-(7,8-Dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide	IC50	47.0 [1]
	2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	IC50	27000.0 [1]
	Dactolisib	IC50	34.0 [1]
	Idelalisib	IC50	10000.0 [1]
	PI-103	IC50	1000.0 [1]
	Torin 1	IC50	176.0 [1]
	Apitolisib	IC50	1300.0 [1]
	Torin 2	IC50	28.1 [1]
	Taselisib	IC50	10000.0 [1]
	CID 72709209	IC50	10000.0 [1]
	5-(7-(Methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine	IC50	10000.0 [1]
	(S)-2-(2-(2-Methylindolin-1-yl)-2-oxoethyl)-6-morpholinopyrimidin-4(3H)-one	IC50	10000.0 [1]
	4-[2-[(6-Methoxypyridin-3-yl)amino]-5-[(4-methylsulfonylpiperazin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine	IC50	10000.0 [1]
	Chembl4126156	IC50	10000.0 [1]
	(2S)-N1-[5-(2-Tert-butyl-4-thiazolyl)-4-methyl-2-thiazolyl]pyrrolidine-1,2-dicarboxamide	IC50	5000.0 [1]
	Vps34-IN-1	IC50	10000.0 [1]
	Chmfl-PI3KD-317	IC50	10000.0 [1]
	1-[4-(3-Methyl-2-oxo-8-quinolin-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]cyclopropane-1-carbonitrile	IC50	34.0 [1]
	4-[(3-Chloro-4-fluorophenyl)methyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one	IC50	140.0 [1]
	3-(6-Morpholin-4-yl-8-oxa-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-4-yl)phenol	IC50	1000.0 [1]
	(2S)-2-Amino-N-[5-[6-chloro-5-[(4-methylphenyl)sulfonylamino]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]-3-methylbutanamide	IC50	1518.0 [1]
	(2S)-2-Amino-N-[5-[6-chloro-5-[(2-methylphenyl)sulfonylamino]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]-3-methylbutanamide	IC50	2675.0 [1]
	4-[(3-Chloro-4-fluorophenyl)methyl]-6-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one	IC50	140.0 [1]
	SureCN6875931	IC50	1110.0 [1]
	CID 58441401	IC50	1000.0 [1]
	(2S)-N-[5-(6-Aminopyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]-4,4,4-trifluoro-2-methylbutanamide	IC50	4800.0 [1]
	N-[5-(6-Aminopyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]-4,4,4-trifluoro-2,2-dimethylbutanamide	IC50	12000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 30 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/phosphatidylinositol-4-phosphate-3-kinase-c2-domain-containing-subunit-alpha-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphatidylinositol-4-phosphate-3-kinase-c2-domain-containing-subunit-alpha-inhibitors-ic50-ki.
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