Name: Phosphodiesterase 6C Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Phosphodiesterase 6C Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	Sildenafil	IC50	24.0 ^[1], 39.2 ^[2], 160.0 ^[3]
	Tadalafil	IC50	10000.0 ^[1]
	8-[(4-Chlorophenyl)methyl]-10-thia-3,5,6,8-tetrazatetracyclo[7.7.0.02,6.011,16]hexadeca-1(9),2,4,11(16)-tetraen-7-one	IC50	460.0 ^[1]
	3,7-Bis(2-hydroxyethyl)icaritin	IC50	30900.0 ^[1]
	5-(5-Acetyl-2-butoxypyridin-3-yl)-3-ethyl-2-(1-ethylazetidin-3-yl)-6H-pyrazolo[4,3-d]pyrimidin-7-one	IC50	840.0 ^[1]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Phosphodiesterase 6C Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 Jan. 2026, https://www.aatbio.com/data-sets/phosphodiesterase-6c-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2026, January 9). Quest Database™ Phosphodiesterase 6C Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/phosphodiesterase-6c-inhibitors-ic50-ki.
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