 | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | IC50 | 1775.0 [1] |
 | Idelalisib | IC50 | 89.0 [1] |
 | Pictilisib | IC50 | 75.0 [1] |
| Pictilisib | Ki | 1.4 [1] |
 | Dactolisib | IC50 | 23.6 [1] |
 | PI-103 | IC50 | 48.0 [1] |
 | 4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine | IC50 | 38.0 [1] |
 | Wortmannin | IC50 | 5.0 [1], 19.0 [2], 89.0 [3], 55000.0 [4] |
 | N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide | IC50 | 16.0 [1], 17.0 [2] |
| N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide | Ki | 7.0 [1] |
 | 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one | IC50 | 29000.0 [1], 61000.0 [2], 70000.0 [3] |
 | AS-252424 | IC50 | 30.0 [1], 33.0 [2] |
 | N-[6-(5-Methylsulfonylpyridin-3-Yl)-[1,2,4]triazolo[1,5-A]pyridin-2-Yl]ethanamide | IC50 | 79.43 [1], 1995.26 [2], 63095.73 [3] |
 | (2S)-1-N-[5-(2-Tert-butylpyrimidin-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide | IC50 | 210.0 [1], 230.0 [2], 1500.0 [3] |
 | 6-(5-(Methylsulfonyl)pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine | IC50 | 100.0 [1], 1995.26 [2] |
 | 5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide | IC50 | 25.12 [1], 1000.0 [2], 1995.26 [3] |
 | Chembl4126773 | IC50 | 140.0 [1], 170.0 [2], 500.0 [3] |
| Chembl4126773 | Ki | 4.0 [1] |
 | Buparlisib | IC50 | 262.0 [1], 372.0 [2], 778.0 [3] |
 | Alpelisib | IC50 | 250.0 [1] |
 | 5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione | IC50 | 8.0 [1], 9.0 [2] |
 | Duvelisib | IC50 | 2.9 [1], 12.0 [2], 100.0 [3] |
 | Tgx-221 | IC50 | 1000.0 [1], 10000.0 [2] |
 | Apitolisib | IC50 | 14.0 [1], 36.0 [2] |
 | Gedatolisib | IC50 | 5.4 [1], 11.0 [2] |
 | 5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione | IC50 | 250.0 [1] |
 | 1-[4-(3-Ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea | IC50 | 9.0 [1], 9.2 [2], 16.0 [3] |
 | CID 46927938 | Ki | 179.0 [1] |
 | (3-(9-(1-Benzylpiperidin-4-yl)-6-morpholino-9H-purin-2-yl)phenyl)methanol | IC50 | 1134.0 [1] |
 | (2S)-N1-[5-(2-Tert-butyl-4-thiazolyl)-4-methyl-2-thiazolyl]pyrrolidine-1,2-dicarboxamide | IC50 | 8000.0 [1], 10000.0 [2] |
 | 2-((9H-Purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3H)-one | IC50 | 2030.0 [1], 17000.0 [2] |
 | 3-(4-Morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol;hydrochloride | IC50 | 660.0 [1] |
 | 2-[(1-Methyl-1h-Benzimidazol-2-Yl)methyl]-6-Morpholin-4-Ylpyrimidin-4(3h)-One | IC50 | 10000.0 [1] |
 | N-(5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)pyridin-3-yl)-4-chlorobenzenesulfonamide | IC50 | 6.31 [1], 1995.26 [2], 15848.93 [3] |
 | 5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-isopropylpyridine-3-sulfonamide | IC50 | 31.62 [1], 630.96 [2], 1584.89 [3] |
 | N-[6-(3-Methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]acetamide | IC50 | 501.19 [1], 3981.07 [2], 12589.25 [3] |
 | 5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-benzylpyridine-3-sulfonamide | IC50 | 251.19 [1], 1258.93 [2], 7943.28 [3] |
 | 5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(cyclopropylmethyl)pyridine-3-sulfonamide | IC50 | 15.85 [1], 1584.89 [2], 1995.26 [3] |
 | 5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-naphthalen-1-ylpyridine-3-sulfonamide | IC50 | 7.94 [1], 501.19 [2], 19952.62 [3] |
 | Caffeine | IC50 | 1000000.0 [1], 3630000.0 [2] |
 | Theophylline | IC50 | 800000.0 [1], 2904000.0 [2] |
 | Ku-0063794 | IC50 | 30000.0 [1] |
 | Omipalisib | IC50 | 0.6 [1], 0.61 [2] |
 | Pilaralisib | IC50 | 23.0 [1], 36.0 [2] |
 | N-(7,8-Dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide | IC50 | 18.0 [1], 180.0 [2] |
 | 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | IC50 | 1100.0 [1] |
 | Gne-477 | IC50 | 15.0 [1] |
 | Leniolisib | IC50 | 2230.0 [1], 7400.0 [2] |
 | 5-(7-(Methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine | IC50 | 36.0 [1] |
 | 5-(2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide | IC50 | 25.12 [1] |
 | 4-[2-[(6-Methoxypyridin-3-yl)amino]-5-[(4-methylsulfonylpiperazin-1-yl)methyl]pyridin-3-yl]-6-methyl-1,3,5-triazin-2-amine | Ki | 4.0 [1], 8.0 [2] |
 | pi3K|A Inhibitor C52 | IC50 | 41.0 [1], 170.0 [2] |
 | 1-[6-(5-Methoxypyridin-3-Yl)-1,3-Benzothiazol-2-Yl]-3-[2-(1-Propyl-1h-Imidazol-4-Yl)ethyl]urea | Ki | 2.0 [1] |
 | 3-[4-Amino-1-(1-Methylethyl)-1h-Pyrazolo[3,4-D]pyrimidin-3-Yl]phenol | IC50 | 1500.0 [1] |
 | 2-[[4-Amino-3-(3-fluoro-5-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one | IC50 | 33.0 [1] |
 | 5-Chloro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)ethyl]quinazolin-4-one | IC50 | 12.0 [1] |
 | (5Z)-5-[[5-(4-Hydroxyphenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 380.0 [1] |
 | 4-[(4-Tert-butylphenyl)methyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 2.42 [1], 10.2 [2] |
 | (2S)-1-N-[5-(3-Fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide | IC50 | 10000.0 [1] |
| (2S)-1-N-[5-(3-Fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide | Ki | 3060.0 [1] |
 | 3-[5-(2,4-Dioxothiazolidin-5-ylidenemethyl)furan-2-yl]benzoic acid methyl ester | IC50 | 13500.0 [1] |
 | 5-(5-Pyridin-3-ylfuran-2-ylmethylene)thiazolidine-2,4-dione | IC50 | 950.0 [1] |
 | 5-[5-(2-Hydroxy-3-nitrophenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 80.0 [1] |
 | (5Z)-5-[[5-(2-Hydroxyphenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 30.0 [1] |
 | 5-[5-(2-Hydroxy-5-chlorophenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 43.0 [1] |
 | 3-[5-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-4-hydroxybenzoic acid | IC50 | 530.0 [1] |
 | 5-(5-Pyridin-2-ylfuran-2-ylmethylene)thiazolidine-2,4-dione | IC50 | 110.0 [1] |
 | 5-[5-(3-Hydroxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 290.0 [1] |
 | 5-[5-(2-Hydroxy-5-methylphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 39.0 [1] |
 | 5-[5-(3-Methoxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 2600.0 [1] |
 | 5-[5-(2-Hydroxy-5-trifluoromethoxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 56.0 [1] |
 | 5-[5-(2,4-Dihydroxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 20.0 [1] |
 | 5-[5-(5-Fluoro-2-hydroxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 37.0 [1] |
 | (5Z)-5-[[5-(Furan-3-yl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 840.0 [1] |
 | 5-[5-(2-Fluoro-4-hydroxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 260.0 [1] |
 | (5Z)-5-[[5-(1,3-Benzodioxol-5-yl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 20000.0 [1] |
 | 3-[5-(2,4-Dioxothiazolidin-5-ylidenemethyl)furan-2-yl]-4-hydroxybenzonitrile | IC50 | 40.0 [1] |
 | (5Z)-5-[[5-(5-Nitrofuran-2-yl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 20000.0 [1] |
 | 5-[5-(2,5-Dihydroxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione | IC50 | 20.0 [1] |
 | 8-[(3,5-Difluoro-N-methylanilino)methyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide | IC50 | 1400.0 [1] |
 | 1-[4-[4-[5-Amino-6-(benzotriazol-1-yl)pyrazin-2-yl]pyrazol-1-yl]piperidin-1-yl]-2-(dimethylamino)ethanone | IC50 | 280.0 [1] |
 | 3-(5-((4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid | IC50 | 920.0 [1] |
 | 2-[4-(Morpholin-4-Yl)-6-Oxo-1,6-Dihydropyrimidin-2-Yl]-N-Phenylacetamide | IC50 | 10000.0 [1] |
 | 3-(6-Morpholino-9H-purin-2-yl)phenol | IC50 | 2343.0 [1] |
 | pi-103 (Hydrochloride) | IC50 | 250.0 [1] |
 | 8-(4-Fluoro-2-methylphenoxy)-2-(morpholin-4-yl)quinolin-4(1H)-one | IC50 | 10000.0 [1], 18150.0 [2] |
 | 3-(2,4-Diaminopteridin-6-yl)phenol | IC50 | 39.9 [1], 127.0 [2] |
 | 4-[2-(3,5-Dimethylphenyl)ethyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 2.65 [1], 11.2 [2] |
 | 4-[2-(3-Chlorophenyl)ethyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 4.27 [1], 18.0 [2] |
 | 4-[2-(3-Methoxyphenyl)ethyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 2.66 [1], 11.22 [2] |
 | 4-[2-(4-Chlorophenyl)ethyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 4.76 [1], 20.1 [2] |
 | 4-[2-(4-Methoxyphenyl)ethyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 6.57 [1], 27.7 [2] |
 | 4-[(3,4-Dimethylphenyl)methyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 2.59 [1], 11.0 [2] |
 | 4-[(4-Chlorophenyl)methyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 7.16 [1], 30.0 [2] |
 | 4-Benzyl-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 23.0 [1], 97.0 [2] |
 | 4-[2-(4-Methylphenyl)ethyl]-6-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-1,4-benzoxazin-3-one | IC50 | 8.83 [1], 37.3 [2] |
 | 6-[(Z)-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-4-[[4-(trifluoromethyl)phenyl]methyl]-1,4-benzoxazin-3-one | IC50 | 27.5 [1], 116.0 [2] |
 | 6-[(Z)-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-4-(2-phenylethyl)-1,4-benzoxazin-3-one | IC50 | 24.5 [1], 103.4 [2] |
 | 1-Methyl-3-Naphthalen-2-Yl-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine | IC50 | 570.0 [1] |
 | 1-(1-Methylethyl)-3-Quinolin-6-Yl-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine | IC50 | 43.0 [1] |
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