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Poly [ADP-ribose] polymerase 10 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
▲
▼
4,4'-OxydibenzamideIC50329.0 [1], 330.0 [2], 600.0 [3], 640.0 [4], 1350.0 [5]
OlaparibIC501258.93 [1], 9332.54 [2]
N~2~,N~2~-Dimethyl-N~1~-(6-oxo-5,6-dihydrophenanthridin-2-YL)glycinamideIC505888.44 [1], 6760.83 [2]
VeliparibIC501905.46 [1], 43651.58 [2]
RucaparibIC50562.34 [1], 2290.87 [2]
NiraparibIC501949.84 [1], 3311.31 [2]
3,4-Dihydroisoquinolin-1(2H)-oneIC5030000.0 [1], 128824.96 [2]
4-[(2-Fluorophenyl)methoxy]benzamideIC50234.42 [1], 2000.0 [2]
7-Methoxy-3,4-dihydroisoquinolin-1(2H)-oneIC50100000.0 [1], 169824.37 [2]
7-Methyl-3,4-dihydroisoquinolin-1(2H)-oneIC50100000.0 [1], 112201.85 [2]
7-Fluoro-3,4-dihydroisoquinolin-1(2H)-oneIC5072443.6 [1], 100000.0 [2]
4-(4-Formyl-phenoxy)-benzamideIC50616.6 [1], 1000.0 [2]
7-(Trifluoromethyl)-3,4-dihydroisoquinolin-1(2H)-oneIC5066069.34 [1], 100000.0 [2]
Bmn-673 8R,9SIC507762.47 [1]
4-MethoxybenzamideIC502800.0 [1]
5-(2-Oxo-2-phenylethoxy)isoquinolin-1(2H)-oneIC507079.46 [1]
4-Quinazolinol, 5,6,7,8-tetrahydro-2-(4-methyl-1-piperazinyl)-IC5010000.0 [1]
7-Chloro-3,4-dihydroisoquinolin-1(2H)-oneIC50100000.0 [1]
CID 21950586IC501148.15 [1]
Morpholin-4-Yl[4-(Tetrazolo[1,5-A]quinoxalin-4-Ylamino)phenyl]methanoneIC505011.87 [1]
4-(Benzyloxy)benzamideIC501348.96 [1]
2-(4-Tert-Butylphenyl)-2,3-dihydroquinazoline-4(1H)-oneIC5010000.0 [1]
4-EthoxybenzamideIC503500.0 [1]
4-[(4-Fluorobenzyl)oxy]benzamideIC507943.28 [1]
(2z)-4-[(3-Carbamoylphenyl)amino]-4-Oxobut-2-Enoic AcidIC5010715.19 [1]
4-(4-Carbamoylphenoxy)benzoic acidIC50180.0 [1]
4-[(3-Fluorophenyl)methoxy]benzamideIC503311.31 [1]
(2E)-4-[(3-Carbamoylphenyl)amino]-4-oxobut-2-enoic acidIC501380.38 [1]
N-(3-Carbamoyl-phenyl)-succinamic acidIC501905.46 [1]
4-CyclobutoxybenzamideIC50720.0 [1]
N-{4-[(2-Chlorophenyl)(Pyrimidin-4-Yl)carbamoyl]phenyl}-4-MethoxybenzamideIC5010000.0 [1]
4-(4-Methoxyphenoxy)benzamideIC501400.0 [1]
(Z)-4-(5-Carbamoyl-2-methoxyanilino)-4-oxobut-2-enoic acidIC5020000.0 [1]
(Z)-4-(3-Carbamoylanilino)-3-methyl-4-oxobut-2-enoic acidIC5020000.0 [1]
(Z)-4-(3-Carbamoylanilino)-2-methyl-4-oxobut-2-enoic acidIC5014125.38 [1]
4-(3-Carbamoylanilino)-3-methoxy-4-oxobutanoic acidIC507244.36 [1]
2-[(3-Carbamoylphenyl)carbamoyl]cyclopentene-1-carboxylic acidIC502884.03 [1]
3-(3,4-Dimethyl-2,5-dioxopyrrol-1-yl)benzamideIC502398.83 [1]
(Z)-N'-(3-Carbamoylphenyl)-N-methylbut-2-enediamideIC501995.26 [1]
(E)-N'-(3-Carbamoylphenyl)-N-methylbut-2-enediamideIC502089.3 [1]
3-[[(Z)-4-Oxo-4-pyrrolidin-1-ylbut-2-enoyl]amino]benzamideIC504570.88 [1]
(Z)-N-(3-Carbamoylphenyl)-N',N'-diethylbut-2-enediamideIC5020000.0 [1]
Methyl (Z)-4-(3-carbamoylanilino)-4-oxobut-2-enoateIC50758.58 [1]
3-(5-Oxohexanoylamino)benzamideIC5014454.4 [1]
3-[(3-Oxocyclopentanecarbonyl)amino]benzamideIC506918.31 [1]
2-(2,4-Dioxo-1,3-diazinan-1-yl)-N-[2-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)ethyl]benzamideIC502187.76 [1]
2-(2,4-Dioxo-1,3-diazinan-1-yl)-N-[(4-pyrazol-1-ylphenyl)methyl]benzamideIC5050000.0 [1]
N-[2-(2,4-Dichlorophenyl)ethyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamideIC5050000.0 [1]
N-[2-(4-Bromophenyl)ethyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamideIC5050000.0 [1]
N-[2-(4-Chlorophenyl)ethyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamideIC5050000.0 [1]
N-[(2S)-3-Amino-2-[[2-(6-methoxy-3-oxo-1,2-dihydroinden-1-yl)acetyl]amino]-3-oxopropyl]-2-(2,4-dioxo-1,3-diazinan-1-yl)benzamideIC5050000.0 [1]
1-[2-[4-[2-(6-Methoxy-3-oxo-1,2-dihydroinden-1-yl)acetyl]piperazine-1-carbonyl]phenyl]-1,3-diazinane-2,4-dioneIC5033884.42 [1]
1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrileIC5010000.0 [1]
4-[3-[4-(4-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC50400.0 [1]
2-(4-((Pyridin-4-Yl)methyl)piperazin-1-Yl)-3,4,5,6,7,8-Hexahydroquinazolin-4-OneIC505400.0 [1]
4-[3-(4-Oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamideIC50100000.0 [1]
4-[3-(8-Methyl-4-oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamideIC50100000.0 [1]
4-[4-[4-(4-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC501650.0 [1]
4-[3-[4-(2-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC50470.0 [1]
4-[3-(3-Phenylpiperidine-1-carbonyl)phenoxy]benzamideIC50600.0 [1]
Ethyl 1-[3-(4-carbamoylphenoxy)benzoyl]piperidine-4-carboxylateIC501060.0 [1]
4-[3-[4-(3-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC50250.0 [1]
4-[3-[4-(3-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC50467.74 [1]
4-[3-[4-(4-Chlorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC502511.89 [1]
4-[3-(2-Phenylpiperidine-1-carbonyl)phenoxy]benzamideIC501100.0 [1]
4-[3-(4-Phenylpiperazine-1-carbonyl)phenoxy]benzamideIC501100.0 [1]
4-[3-[4-(4-Fluorophenyl)-4-hydroxypiperidine-1-carbonyl]phenoxy]benzamideIC50387.26 [1]
4-[3-[4-(2-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC50457.09 [1]
4-[4-[4-(3-Fluorophenyl)piperidine-1-carbonyl]phenoxy]benzamideIC501220.0 [1]
4-[3-[4-(3,4-Difluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC502818.38 [1]
4-[3-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]phenoxy]benzamideIC502818.38 [1]
4-[3-(4-Phenylpiperidine-1-carbonyl)phenoxy]benzamideIC50580.0 [1]
4-[3-[4-(4-Fluorophenyl)piperazine-1-carbonyl]phenoxy]benzamideIC501348.96 [1]
4-[3-(3-Phenylpyrrolidine-1-carbonyl)phenoxy]benzamideIC50780.0 [1]
4-[3-(4-Hydroxy-4-phenylpiperidine-1-carbonyl)phenoxy]benzamideIC501520.55 [1]
N-(4-Propan-2-ylphenyl)tetrazolo[1,5-a]quinoxalin-4-amineIC505011.87 [1]
7-Bromo-3,4-dihydroisoquinolin-1(2H)-oneIC50100000.0 [1]
4-[(4-Carbamoylphenoxy)methyl]benzamideIC502290.87 [1]
4-[(3-Bromobenzyl)oxy]benzamideIC502187.76 [1]
4-[(3,5-Dimethylphenyl)methoxy]benzamideIC504570.88 [1]
5-(3-Carbamoylanilino)-5-oxopentanoic acidIC507413.1 [1]
4-(4-Aminophenoxy)benzamideIC501300.0 [1]
1,2-Dihydro-2-(4-isopropylphenyl)-4(3H)-quinazolinoneIC5010000.0 [1]
7-Hydroxy-3,4-dihydro-2H-isoquinolin-1-oneIC5030000.0 [1]
4-(Propan-2-yloxy)benzamideIC501300.0 [1]
4-(2-Phenoxyethoxy)benzamideIC501949.84 [1]
3-(4-Oxopentanoylamino)benzamideIC501905.46 [1]
2-[(3-Carbamoylphenyl)carbamoyl]cyclopropane-1-carboxylic acidIC5014125.38 [1]
4-(4-Hydroxyphenoxy)benzamideIC501800.0 [1]
4-(3-Carbamoylanilino)-2,2-dimethyl-4-oxobutanoic acidIC5020000.0 [1]
4-[(2-Bromophenyl)methoxy]benzamideIC503801.89 [1]
4-(2-Fluorophenoxy)benzamideIC501698.24 [1]
Chembl4126054IC50510.0 [1]
[4-(1-Methylimidazole-4-carbonyl)piperazin-1-yl]-[4-(tetrazolo[1,5-a]quinoxalin-4-ylamino)phenyl]methanoneIC505011.87 [1]
4-[(Naphthalen-1-yl)methoxy]benzamideIC501445.44 [1]
4-(2-Pyridinylmethoxy)benzamideIC501348.96 [1]
4-[(4-Methylphenyl)methoxy]benzamideIC509332.54 [1]
Benzamide, 4-(benzoyloxy)-IC507244.36 [1]
N-[3-Chloranyl-4-[[4-(4-Methoxyphenyl)oxan-4-Yl]methylcarbamoyl]phenyl]furan-2-CarboxamideIC5010000.0 [1]
Items per page: 1 - 10 of 99
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References

This online tool may be cited as follows

MLA

"Quest Database™ Poly [ADP-ribose] polymerase 10 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-10-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Poly [ADP-ribose] polymerase 10 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/poly-adp-ribose-polymerase-10-inhibitors-ic50-ki.
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