 | Mifepristone | IC50 | 0.2 [1] |
| Mifepristone | Ki | 0.25 [1], 0.64 [2] |
 | Dexamethasone | IC50 | 2000.0 [1] |
| Dexamethasone | Ki | 561.0 [1], 778.0 [2] |
 | Prednisolone | IC50 | 2000.0 [1], 2080.0 [2], 27000.0 [3] |
 | Medroxyprogesterone acetate | IC50 | 10.8 [1], 10000.0 [2] |
 | Onapristone | IC50 | 1.6 [1], 3.3 [2] |
| Onapristone | Ki | 18.0 [1] |
 | 2,2,4-Trimethyl-6-(3-nitrophenyl)-1,2-dihydroquinoline | IC50 | 41.0 [1], 42.0 [2] |
| 2,2,4-Trimethyl-6-(3-nitrophenyl)-1,2-dihydroquinoline | Ki | 19.95 [1], 20.0 [2] |
 | 3-Fluoro-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)benzonitrile | IC50 | 30.0 [1], 37.0 [2] |
| 3-Fluoro-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)benzonitrile | Ki | 10.0 [1] |
 | Spironolactone | IC50 | 650.0 [1], 1400.0 [2], 4000.0 [3], 10000.0 [4] |
| Spironolactone | Ki | 399.7 [1] |
 | Eplerenone | IC50 | 10000.0 [1], 20000.0 [2] |
 | 1,2-Dihydro-2,2,4-trimethyl-5-(4-chlorophenyl)-5H-1-aza-6-oxachrysene | IC50 | 600.0 [1] |
| 1,2-Dihydro-2,2,4-trimethyl-5-(4-chlorophenyl)-5H-1-aza-6-oxachrysene | Ki | 0.7 [1] |
 | 1,2-Dihydro-2,2,4-trimethyl-6-phenylquinoline | IC50 | 783.0 [1] |
| 1,2-Dihydro-2,2,4-trimethyl-6-phenylquinoline | Ki | 131.83 [1], 133.0 [2] |
 | (E)-3-[3,5-Difluoro-4-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acid | IC50 | 0.28 [1], 11.22 [2], 540.0 [3], 3162.28 [4] |
 | 2,2,4,9-Tetramethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | IC50 | 100.0 [1] |
| 2,2,4,9-Tetramethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | Ki | 44.67 [1], 45.0 [2], 50.2 [3] |
 | 9-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | IC50 | 335.0 [1] |
| 9-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | Ki | 6.1 [1], 19.3 [2], 19.5 [3] |
 | 2,2,4-Trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | IC50 | 138.0 [1] |
| 2,2,4-Trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | Ki | 83.18 [1], 84.0 [2] |
 | 4-Methyl-5-(2,2,4,4-tetramethyl-3-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carbonitrile | IC50 | 10.0 [1] |
| 4-Methyl-5-(2,2,4,4-tetramethyl-3-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carbonitrile | Ki | 3.89 [1], 3.9 [2] |
 | 1-Methyl-5-(2-oxochromen-6-yl)pyrrole-2-carbonitrile | IC50 | 65.0 [1], 123.0 [2], 15200.0 [3] |
 | 3-(2-Oxospiro[1H-indole-3,1'-cyclohexane]-5-yl)benzonitrile | IC50 | 6.6 [1], 14.7 [2], 15.0 [3], 25.0 [4] |
 | 3-(4,4-Dimethyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)-5-fluorobenzonitrile | IC50 | 15.9 [1], 16.0 [2], 90.0 [3] |
 | 5-(4,4-Dimethyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)-2-fluorobenzonitrile | IC50 | 15.0 [1], 15.1 [2], 55.0 [3] |
 | 6-(3-Nitro-phenyl)-3H-benzothiazol-2-one | IC50 | 83.8 [1], 84.0 [2], 326.0 [3] |
| 6-(3-Nitro-phenyl)-3H-benzothiazol-2-one | Ki | 332.0 [1] |
 | 6-(5-Cyano-3-thienyl)-1,2-dihydro-2,2,4-trimethylquinoline | IC50 | 24.0 [1], 106.0 [2] |
| 6-(5-Cyano-3-thienyl)-1,2-dihydro-2,2,4-trimethylquinoline | Ki | 3.47 [1], 3.5 [2] |
 | 2,2,4-Trimethyl-6-(3-methyl-2-thienyl)-1,2-dihydroquinoline | IC50 | 105.0 [1], 232.0 [2] |
| 2,2,4-Trimethyl-6-(3-methyl-2-thienyl)-1,2-dihydroquinoline | Ki | 25.0 [1], 25.12 [2] |
 | 2,2,4-Trimethyl-6-(5-chloro-2-thienyl)-1,2-dihydroquinoline | IC50 | 43.0 [1], 151.0 [2] |
| 2,2,4-Trimethyl-6-(5-chloro-2-thienyl)-1,2-dihydroquinoline | Ki | 12.0 [1], 12.02 [2] |
 | 2,2,4-Trimethyl-6-(5-nitro-2-thienyl)-1,2-dihydroquinoline | IC50 | 31.0 [1], 70.0 [2] |
| 2,2,4-Trimethyl-6-(5-nitro-2-thienyl)-1,2-dihydroquinoline | Ki | 2.57 [1], 2.6 [2] |
 | 5-(2,2,4-Trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | IC50 | 27.0 [1], 80.0 [2] |
| 5-(2,2,4-Trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | Ki | 54.95 [1], 55.0 [2] |
 | 6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one | IC50 | 73.0 [1], 112.8 [2], 412.0 [3] |
| 6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoimidazol-2-one | Ki | 525.0 [1] |
 | 2,2,4-Trimethyl-6-(4-bromo-2-thienyl)-1,2-dihydroquinoline | IC50 | 105.0 [1], 190.0 [2] |
| 2,2,4-Trimethyl-6-(4-bromo-2-thienyl)-1,2-dihydroquinoline | Ki | 32.0 [1], 32.36 [2] |
 | 2,2,4-Trimethyl-6-(5-bromo-2-thienyl)-1,2-dihydroquinoline | IC50 | 65.0 [1], 71.0 [2] |
| 2,2,4-Trimethyl-6-(5-bromo-2-thienyl)-1,2-dihydroquinoline | Ki | 30.9 [1], 31.0 [2] |
 | 4-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)-3,5-dimethylthiophene-2-carbonitrile | IC50 | 124.0 [1], 150.0 [2] |
| 4-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)-3,5-dimethylthiophene-2-carbonitrile | Ki | 36.0 [1], 36.31 [2] |
 | 4-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)thiophene-2-carbaldehyde | IC50 | 102.0 [1], 245.0 [2] |
| 4-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)thiophene-2-carbaldehyde | Ki | 37.0 [1], 37.15 [2] |
 | 4-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)-5-methylthiophene-2-carbonitrile | IC50 | 109.0 [1], 120.0 [2] |
| 4-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)-5-methylthiophene-2-carbonitrile | Ki | 30.9 [1], 31.0 [2] |
 | 4-Methyl-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | IC50 | 33.0 [1], 123.0 [2] |
| 4-Methyl-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | Ki | 25.7 [1], 26.0 [2] |
 | 3-Bromo-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | IC50 | 242.0 [1], 250.0 [2] |
| 3-Bromo-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | Ki | 249.0 [1], 251.19 [2] |
 | 2,2,4-Trimethyl-6-(2-thienyl)-1,2-dihydroquinoline | IC50 | 416.0 [1], 700.0 [2] |
| 2,2,4-Trimethyl-6-(2-thienyl)-1,2-dihydroquinoline | Ki | 234.42 [1], 237.0 [2] |
 | 5-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)thiophene-2-carbaldehyde | IC50 | 78.0 [1], 729.0 [2] |
| 5-(2,2,4-Trimethyl-1,2-dihydroquinoline-6-yl)thiophene-2-carbaldehyde | Ki | 79.43 [1], 80.0 [2] |
 | 4-Bromo-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | IC50 | 52.0 [1], 120.0 [2] |
| 4-Bromo-5-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)thiophene-2-carbonitrile | Ki | 433.0 [1], 436.52 [2] |
 | 7-(Diethylamino)-6-phenylchromen-2-one | IC50 | 500.0 [1], 1420.0 [2] |
 | 6-(3-Chloro-4-fluorophenyl)-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one | IC50 | 23.0 [1], 37.0 [2] |
 | 4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-furan-2-carbonitrile | IC50 | 8.0 [1], 40.2 [2] |
 | Asoprisnil | IC50 | 0.2 [1], 0.3 [2] |
 | Desmethylmifepristone | IC50 | 0.07 [1], 0.17 [2] |
 | 5-Bromo-2-[[(1S,3R)-3-bromo-2,2-dimethyl-6-methylidenecyclohexyl]methyl]-4-methoxyphenol | IC50 | 354.0 [1], 549.0 [2] |
| 5-Bromo-2-[[(1S,3R)-3-bromo-2,2-dimethyl-6-methylidenecyclohexyl]methyl]-4-methoxyphenol | Ki | 490.0 [1] |
 | 5-(3-Chloro-phenyl)-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene | Ki | 0.32 [1] |
 | 4-(5-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-N-(4-methyl-1-oxo-2,3-benzoxazin-6-yl)-2-(trifluoromethyl)pentanamide | IC50 | 12.59 [1], 22.0 [2] |
 | N-(4-Phenoxyphenyl)-3-trifluoromethylbenzenesulfonamide | IC50 | 33.0 [1], 40.0 [2], 107.0 [3] |
 | 9-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | Ki | 3.6 [1], 12.88 [2], 12.9 [3] |
 | 6-(1-(4-Fluoro-2-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one | IC50 | 1800.0 [1], 1900.0 [2] |
 | 3-(2,2,4-Trimethyl-1,2-dihydroquinolin-6-yl)benzonitrile | IC50 | 38.0 [1] |
| 3-(2,2,4-Trimethyl-1,2-dihydroquinolin-6-yl)benzonitrile | Ki | 19.0 [1], 19.05 [2] |
 | (5Z)-2,2,4-Trimethyl-5-[(2-methylphenyl)methylidene]-1H-chromeno[3,4-f]quinoline | Ki | 0.66 [1] |
 | 7-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline-9-carbonitrile | IC50 | 149.0 [1] |
| 7-Fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline-9-carbonitrile | Ki | 4.47 [1], 4.5 [2] |
 | 5-Phenyl-2,2,4-trimethyl-1,2-dihydro-5H-1-aza-6-oxachrysene | IC50 | 290.0 [1] |
| 5-Phenyl-2,2,4-trimethyl-1,2-dihydro-5H-1-aza-6-oxachrysene | Ki | 3.6 [1] |
 | 2,2,4-Trimethyl-6-(3,5-difluorophenyl)-1,2-dihydroquinoline | IC50 | 79.0 [1] |
| 2,2,4-Trimethyl-6-(3,5-difluorophenyl)-1,2-dihydroquinoline | Ki | 10.0 [1] |
 | 2,2,4-Trimethyl-6-(3-nitro-5-fluorophenyl)-1,2-dihydroquinoline | IC50 | 70.0 [1] |
| 2,2,4-Trimethyl-6-(3-nitro-5-fluorophenyl)-1,2-dihydroquinoline | Ki | 5.0 [1], 5.01 [2] |
 | 2,2,4-Trimethyl-6-(3-fluorophenyl)-1,2-dihydroquinoline | IC50 | 750.0 [1] |
| 2,2,4-Trimethyl-6-(3-fluorophenyl)-1,2-dihydroquinoline | Ki | 181.97 [1], 182.0 [2] |
 | 5-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile | IC50 | 5.6 [1], 26.2 [2] |
 | 5-(3-Chlorophenyl)spiro[1H-indole-3,1'-cyclohexane]-2-one | IC50 | 56.0 [1], 477.0 [2] |
 | 1,3,3-Trimethyl-4,11-dihydro-3H-indeno[2,1-f]quinoline | IC50 | 549.0 [1] |
| 1,3,3-Trimethyl-4,11-dihydro-3H-indeno[2,1-f]quinoline | Ki | 12.88 [1], 13.0 [2] |
 | 9-Bromo-1,3,3-trimethyl-4,11-dihydro-3H-indeno[2,1-f]quinoline | IC50 | 2330.0 [1] |
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