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Prostanoid FP receptor Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
DinoprostIC502.5 [1], 3.0 [2], 7.0 [3], 43.0 [4]
DinoprostKi119.0 [1]
CloprostenolIC501.0 [1], 2.0 [2]
CloprostenolKi31.0 [1]
Acetic acid, (3-(((1S)-2-(4,5-diphenyl-2-oxazolyl)-2-cyclohexen-1-yl)methyl)phenoxy)-, sodium saltKi1000.0 [1]
2-[(3R)-5-Acetyl-4-[(4-chlorophenyl)methyl]-7-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acidKi20000.0 [1]
13,14-Dihydro-16-m-chlorophenoxy-w-tetranor-PGF1alphaIC501.0 [1], 2.6 [2]
2-[(3R)-4-[(4-Chlorophenyl)methyl]-5-(1-hydroxyethyl)-7-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acidKi20000.0 [1]
7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-pentyl)-cyclopentyl]-heptanoic acidIC5082.0 [1], 570.0 [2]
13,14-Dihydro PGF-1aIC50350.0 [1], 522.0 [2]
3-(2-(Naphthalen-2-ylmethyl)phenyl)acrylic acidKi500.0 [1], 69000.0 [2]
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3R)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pentyl]cyclopentyl]heptanoic acidIC508.6 [1]
LaropiprantKi9991.0 [1]
GrapiprantKi5000.0 [1]
FevipiprantIC5010000.0 [1]
(2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamideKi500.0 [1]
7-[2-(3-Hydroxyoctyl)-5-oxopyrrolidin-1-YL]heptanoic acidKi13000.0 [1]
16,16-Dimethylprostaglandin F2alphaIC5016.0 [1]
CID 24952929Ki24000.0 [1]
Nvp-qav680IC5010000.0 [1]
CID 15948325Ki2000.0 [1]
Unii-Z1avz44tejKi1.0 [1]
1-(2,6-Dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamideKi340.0 [1]
FK-788Ki10000.0 [1]
2-Pyridinecarboxylic acid, 6-(5'-chloro-2'-(2-methylpropoxy)(1,1'-biphenyl)-2-yl)-, sodium saltIC5010000.0 [1]
Sodium 6-((5-chloro-2-(((4-chloro-2-fluorophenyl)methyl)oxy)phenyl)methyl)-2-pyridinecarboxylateIC5010000.0 [1]
(2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)indol-1-yl]methyl]phenoxy]propanoic acidIC502730.0 [1]
(E)-3-[2-(3,4-Dichlorophenyl)phenyl]-N-thiophen-2-ylsulfonylprop-2-enamideKi17000.0 [1]
4-[(1S)-1-[[5-Chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acidKi6000.0 [1]
2-(1-(3,4-Difluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acidIC5010000.0 [1]
7-{(R)-2-[(E)-3-Hydroxy-3-(1-phenyl-cyclopropyl)-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acidKi13000.0 [1]
2-[1-[2-(N-Benzoyl-4-methylanilino)ethyl]piperidin-4-yl]oxyacetic acidKi50000.0 [1]
{4-[4,9-Bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acidIC5010000.0 [1]
Sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetateKi1000.0 [1]
(S)-4-(1-(1-(3-Chlorobenzyl)-1H-indole-7-carboxamido)ethyl)benzoic acidKi2500.0 [1]
Unii-86KF5vsv88Ki6400.0 [1]
N-[5-(2,6-Dichlorophenyl)-1,3,4-thiadiazol-2-yl]-4-ethyl-2,3-dihydro-1,4-benzoxazine-6-carboxamideKi25118.86 [1]
7-[(R)-2-((E)-3-Hydroxy-4-phenyl-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acidKi13000.0 [1]
5-(6-Naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dioneIC5050118.72 [1]
3-(2-(Naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamideKi500.0 [1]
7-[(1R,2R,3R,5S)-2-[(3R)-5-(3-Fluorophenyl)-3-hydroxypentyl]-3,5-dihydroxycyclopentyl]heptanoic acidIC5042.0 [1]
7-{3,5-Dihydroxy-2-[3-hydroxy-4-(thiophen-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acidIC5011.0 [1]
5-[2-[5-Chloro-2-[(4-fluorophenyl)methoxy]phenyl]-5-methylpyrrol-1-yl]-2-methylbenzoic acidIC503162.28 [1]
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenylsulfanyl-butyl)-cyclopentyl]-heptanoic acidIC503.0 [1]
7-{(2R)-2-[(1E)-3-Hydroxy-3-methyl-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl}heptanoic acidKi13000.0 [1]
(E)-3-[2-(3,4-Dichloro-benzyl)-phenyl]-acrylic acidKi41000.0 [1]
(Z)-7-[(1R,2R,3R,6S)-2-[(E,3R)-4-(3-Chlorophenoxy)-3-hydroxybut-1-enyl]-3,6-dihydroxycyclohexyl]hept-5-enoic acidKi1900.0 [1]
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenyl]sulfanylbutyl]cyclopentyl]heptanoic acidIC50320.0 [1]
7-{2-[4-(3-Chloro-phenylsulfanyl)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acidIC5017.0 [1]
(Z)-7-[(1R,2R,3R,6S)-2-[(E,3S)-4-(3-Chlorophenoxy)-3-hydroxybut-1-enyl]-3,6-dihydroxycyclohexyl]hept-5-enoic acidKi56000.0 [1]
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenylamino-butyl)-cyclopentyl]-heptanoic acidIC5090.0 [1]
7-{3,5-Dihydroxy-2-[3-hydroxy-4-(thiazol-2-ylsulfanyl)-butyl]-cyclopentyl}-heptanoic acidIC501424.0 [1]
7-[3,5-Dihydroxy-2-(3-hydroxy-4-m-tolylsulfanyl-butyl)-cyclopentyl]-heptanoic acidIC5063.0 [1]
7-{2-[4-(3-Fluoro-phenylsulfanyl)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acidIC5029.0 [1]
{6-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hex-4-enyl}-methyl-phosphinic acidIC50311.0 [1]
[(Z)-6-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hex-4-enyl]-hydroxy-oxophosphaniumIC50114.0 [1]
{6-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hex-4-enyl}-ethyl-phosphinic acidIC504100.0 [1]
Butyl-{6-[3,5-dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hex-4-enyl}-phosphinic acidIC506700.0 [1]
6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzyloxycarbonylamino-pentanoylamino}-hexanoic acidKi10000.0 [1]
2-[(3R)-5-Acetyl-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acidKi20000.0 [1]
N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-benzamideKi1000.0 [1]
2-[(9R)-10-(4-Chlorobenzoyl)-3-fluoro-1-methylsulfonyl-6,7,8,9-tetrahydropyrido[1,2-a]indol-9-yl]acetic acidKi21057.0 [1]
2-[(1R)-6-Fluoro-8-methylsulfonyl-9-[(1S)-1-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acidKi4320.0 [1]
[(3R)-5-Bromo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]acetic acidKi14000.0 [1]
2-[2-[5-[2-(Benzyloxy)phenyl]-3-thienyl]phenyl]cyclopropane-1-carboxylic acidKi22000.0 [1]
2-[1-[2-[N-(1,3-Benzodioxole-5-carbonyl)-4-methylanilino]ethyl]piperidin-4-yl]oxyacetic acid;hydrate;hydrochlorideKi50000.0 [1]
N-[(4-Chlorophenyl)methyl]-2-(2-ethyl-N-(4-methylphenyl)sulfonylanilino)acetamideIC504168.69 [1]
7-[(R)-2-((E)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acidKi13000.0 [1]
2-(9-(4-Chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acidKi20000.0 [1]
7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyclopentyl]-heptanoic acidIC5012.0 [1]
(E)-N-(5-Bromo-2-methoxyphenyl)sulfonyl-3-[2-[(6-phenylmethoxynaphthalen-2-yl)methyl]phenyl]prop-2-enamideKi500.0 [1]
N-(5-(Pentan-3-yl)-1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamideKi25000.0 [1]
3-(2-((6-(Benzyloxy)naphthalen-2-yl)methyl)phenyl)acrylic acidKi500.0 [1]
Sodium;2-[3-[[(1R,2S,6S)-1-(4,5-diphenyl-1,3-oxazol-2-yl)-7-oxabicyclo[4.1.0]heptan-2-yl]methyl]phenoxy]acetateKi10000.0 [1]
2-[(6S)-5-(3,4-Dichlorophenyl)sulfanyl-4-propan-2-yl-7,8-dihydro-6H-pyrido[4,3-e]pyrrolizin-6-yl]acetic acidKi25700.0 [1]
(S)-4-(1-(1-(3-(Trifluoromethyl)benzyl)-1H-indole-7-carboxamido)ethyl)benzoic acidKi785.0 [1]
(S)-4-(1-(3-Chloro-1-(3-chlorobenzyl)-1H-indole-7-carboxamido)ethyl)benzoic acidKi930.0 [1]
(S)-4-(1-(5-Chloro-1-(3-chlorobenzyl)-1H-indole-7-carboxamido)ethyl)benzoic acidKi110.0 [1]
4-[(1S)-1-({[4-(3-Chlorobenzyl)-3-thienyl]carbonyl}amino)ethyl]-benzoic AcidKi7282.0 [1]
4-[(1S)-1-({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thienyl]carbonyl}-amino)ethyl]benzoic AcidKi456.0 [1]
4-{(1S)-1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]ethyl}benzoic acidKi5474.0 [1]
2,5-Dimethyl-N-[1-[4-(2H-tetrazol-5-yl)phenyl]cyclopropyl]-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carboxamideKi501.0 [1]
4-[(1R)-1-({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thienyl]carbonyl}amino)ethyl]benzoic acidKi224.0 [1]
4-[({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thienyl]carbonyl}amino)methyl]benzoic acidKi628.0 [1]
4-[(1S)-1-({[4-(3-Chlorobenzyl)-2,5-dimethyl-3-thienyl]carbonyl}-amino)ethyl]benzoic AcidKi2226.0 [1]
4-[1-[[2,5-Dimethyl-4-[[3-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]cyclopropyl]benzoic acidKi4992.0 [1]
4-{(1S)-1-[({2,5-Dimethyl-4-[3-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]ethyl}benzoic AcidKi3461.0 [1]
4-[(1S)-1-[[4-[(4-Chlorophenyl)methyl]-2,5-dimethylthiophene-3-carbonyl]amino]ethyl]benzoic acidKi2117.0 [1]
4-(1-(5-Chloro-1-(4-(trifluoromethyl)benzyl)-1H-indole-7-carboxamido)cyclopropyl)benzoic acidKi1291.0 [1]
(E)-3-[1-[(3,4-Difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamideIC503800.0 [1]
2-[(6R)-5-(3,4-Dichlorophenyl)sulfanyl-4-propan-2-yl-7,8-dihydro-6H-pyrido[4,3-e]pyrrolizin-6-yl]acetic acidKi25700.0 [1]
(E)-N-(3,4-Difluorophenyl)sulfonyl-3-(1-methyl-4-naphthalen-2-yloxyindol-3-yl)prop-2-enamideIC503590.0 [1]
7-[(R)-2-(3-Hydroxy-octyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acidKi13000.0 [1]
(R)-5-((E)-3-Hydroxy-4-phenyl-but-1-enyl)-1-[4-(1H-tetrazol-5-ylsulfanyl)-butyl]-pyrrolidin-2-oneKi13000.0 [1]
7-[(S)-2-(3-Hydroxy-octyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acidKi13000.0 [1]
3-[4-[(2R)-2-[(E)-3-Hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl]butylsulfanyl]propanoic acidKi13000.0 [1]
2-[4-[(2R)-2-[(E)-3-Hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl]butylsulfanyl]acetic acidKi13000.0 [1]
7-[(2R)-2-[(E)-3-Hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acidKi13000.0 [1]
(5R)-5-[(E)-3-Hydroxy-4-phenylbut-1-enyl]-1-[4-(2H-tetrazol-5-ylmethylsulfanyl)butyl]pyrrolidin-2-oneKi13000.0 [1]
Methyl 2-[4-[(2R)-2-[(E)-3-hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl]butylsulfanyl]acetateKi13000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Prostanoid FP receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/prostanoid-fp-receptor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 9). Quest Database™ Prostanoid FP receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/prostanoid-fp-receptor-inhibitors-ic50-ki.
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