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Prostanoid IP receptor Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
IloprostIC509.0 [1]
IloprostKi3.2 [1], 6.5 [2]
Acetic acid, (3-(((1S)-2-(4,5-diphenyl-2-oxazolyl)-2-cyclohexen-1-yl)methyl)phenoxy)-, sodium saltIC5060.0 [1]
Acetic acid, (3-(((1S)-2-(4,5-diphenyl-2-oxazolyl)-2-cyclohexen-1-yl)methyl)phenoxy)-, sodium saltKi54.0 [1]
AlprostadilIC501400.0 [1]
AlprostadilKi150.0 [1], 10000.0 [2]
2-[2-Methyl-1-[4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]indol-4-yl]acetic acidKi37.0 [1]
Unii-1H463450OSIC5081.0 [1]
Unii-1H463450OSKi94.0 [1]
RalinepagIC5038.0 [1], 166.0 [2]
RalinepagKi3.0 [1]
2-[[4-[[(3-Fluorophenyl)-phenylcarbamoyl]oxymethyl]cyclohexyl]methoxy]acetic acidIC5018.0 [1], 93.0 [2]
2-[[4-[[(3-Fluorophenyl)-phenylcarbamoyl]oxymethyl]cyclohexyl]methoxy]acetic acidKi7.0 [1]
DinoprostoneIC50260.0 [1]
DinoprostoneKi10000.0 [1]
DinoprostIC5010000.0 [1], 100000.0 [2]
ButaprostIC5037.0 [1]
ButaprostKi10000.0 [1]
Butaprost (free acid form)IC5025.0 [1]
Butaprost (free acid form)Ki870.0 [1]
2-[(3R)-5-Acetyl-4-[(4-chlorophenyl)methyl]-7-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acidKi20000.0 [1]
2-[3-[[4-[[(2S)-4-Methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acidKi6400.0 [1]
2-[(3R)-4-[(4-Chlorophenyl)methyl]-5-(1-hydroxyethyl)-7-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acidKi20000.0 [1]
2-[1-[2-(N-Benzoyl-4-methylanilino)ethyl]piperidin-4-yl]oxyacetic acidIC50130.0 [1]
2-[1-[2-(N-Benzoyl-4-methylanilino)ethyl]piperidin-4-yl]oxyacetic acidKi990.0 [1]
6-[(1R,2S,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]sulfanylhexanoic acidKi870.0 [1]
Sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetateKi12.0 [1]
2-[4-Methyl-3-[[2-methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acidKi2600.0 [1]
2-[4-Chloro-3-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acidKi1600.0 [1]
2-[3-[[2-Chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-4-fluorophenyl]acetic acidKi10000.0 [1]
2-[3-[[2-Methyl-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]acetic acidKi3600.0 [1]
(Z)-7-[(1R,2R,3R,5R)-5-Chloro-2-[(E,4S)-4-(1-ethylcyclobutyl)-4-hydroxybut-1-enyl]-3-hydroxycyclopentyl]hept-5-enoic acidKi10000.0 [1]
3-(2-(Naphthalen-2-ylmethyl)phenyl)acrylic acidKi500.0 [1], 100000.0 [2]
(2S)-2-[(5-{[4-(3-Acetamidophenyl)phenyl]methyl}-1,3-oxazol-4-yl)formamido]-3-phenylpropanoic acidIC5016.0 [1], 476.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-benzyl-1,3-oxazole-4-carboxamideIC5066.0 [1], 561.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-(2-phenylethyl)-1,3-oxazole-4-carboxamideIC50138.0 [1], 721.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-(1-phenylethyl)-1,3-oxazole-4-carboxamideIC50278.0 [1], 1230.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-methyl-N-(2-phenylethyl)-1,3-oxazole-4-carboxamideIC502133.0 [1], 7160.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-[(1S,2R)-2-phenylcyclopropyl]-1,3-oxazole-4-carboxamideIC50331.0 [1], 358.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-[(2R)-2-phenylpropyl]-1,3-oxazole-4-carboxamideIC5051.0 [1], 53.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-[(2S)-2-phenylpropyl]-1,3-oxazole-4-carboxamideIC50296.0 [1], 916.0 [2]
(2R)-2-[(5-{[4-(3-Acetamidophenyl)phenyl]methyl}-1,3-oxazol-4-yl)formamido]-3-phenylpropanoic acidIC50831.0 [1], 4200.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-(2-pyridin-2-ylethyl)-1,3-oxazole-4-carboxamideIC501005.0 [1], 7600.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-(2-pyridin-3-ylethyl)-1,3-oxazole-4-carboxamideIC50741.0 [1], 4950.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-(2-pyridin-4-ylethyl)-1,3-oxazole-4-carboxamideIC50476.0 [1], 4710.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-phenyl-1,3-oxazole-4-carboxamideIC50828.0 [1], 3480.0 [2]
5-{[4-(3-Acetamidophenyl)phenyl]methyl}-N-methyl-1,3-oxazole-4-carboxamideIC503306.0 [1], 12200.0 [2]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N-[2-(dimethylamino)ethyl]-1,3-oxazole-4-carboxamideIC503306.0 [1], 34100.0 [2]
2-[[4-(Diphenylcarbamoyloxymethyl)cyclohexyl]methoxy]acetic acidIC5025.0 [1], 54.0 [2]
Sodium;2-[3-[[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]methyl]phenoxy]acetateIC5048.0 [1]
Sodium;2-[3-[[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]methyl]phenoxy]acetateKi76.0 [1]
5-[[4-(3-Acetamidophenyl)phenyl]methyl]-N,N-dimethyl-1,3-oxazole-4-carboxamideIC503584.0 [1], 12400.0 [2]
2-[[6-[(2E)-2-Benzhydryloxyiminoethyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acidIC50650.0 [1]
2-[[5-[(3E)-3-Benzhydryloxyiminopropyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acidIC50600.0 [1]
CloprostenolIC5010000.0 [1]
6-Isopropoxy-9-oxoxanthene-2-carboxylic acidKi100000.0 [1]
LaropiprantKi6628.0 [1]
RamatrobanIC50100000.0 [1]
SelexipagIC5062.0 [1]
(4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acidIC50288.0 [1]
GrapiprantKi5000.0 [1]
Ono-AE1-259Ki10000.0 [1]
FevipiprantIC5010000.0 [1]
DG-041IC5014414.0 [1]
(2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamideKi500.0 [1]
MK-7246IC50100000.0 [1]
2-(5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acidIC5057900.0 [1]
EvatanepagKi3200.0 [1]
7-[2-(3-Hydroxyoctyl)-5-oxopyrrolidin-1-YL]heptanoic acidKi13000.0 [1]
(Z)-7-[(1R,2R,3S,5S)-2-[(5-Hydroxy-1-benzothiophene-3-carbonyl)amino]-6,6-dimethyl-3-bicyclo[3.1.1]heptanyl]hept-5-enoic acidIC5010000.0 [1]
CID 24952929Ki22000.0 [1]
ActimisIC50100000.0 [1]
Nvp-qav680IC5010000.0 [1]
CID 15948325Ki7000.0 [1]
Ono-AE1-437Ki10000.0 [1]
N-(4-Methylsulfanylphenyl)-4,5-dihydro-1H-imidazol-2-amineKi10000.0 [1]
1-(2,6-Dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamideKi2000.0 [1]
FK-788Ki8.9 [1]
1H-Imidazol-2-amine, 4,5-dihydro-N-[4-(phenylthio)phenyl]-Ki794.33 [1]
3,4,5-Triphenyl-1H-pyrazole-1-nonanoic acidIC50160.0 [1]
Sodium 6-((5-chloro-2-(((4-chloro-2-fluorophenyl)methyl)oxy)phenyl)methyl)-2-pyridinecarboxylateIC501000.0 [1]
(2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)indol-1-yl]methyl]phenoxy]propanoic acidIC506340.0 [1]
13,14-Dihydro-16-m-chlorophenoxy-w-tetranor-PGF1alphaIC5010000.0 [1]
2-[[6-[(2E)-2-Benzhydryloxyiminopentyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acidIC50150.0 [1]
9-(3,4-Diphenyl-pyrazol-1-yl)-nonanoic acidIC50350.0 [1]
(E)-3-[2-(3,4-Dichlorophenyl)phenyl]-N-thiophen-2-ylsulfonylprop-2-enamideKi7300.0 [1]
7-[2-(Dibenzofuran-2-sulfonylamino)-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl]-hept-5-enoic acidIC5010000.0 [1]
7-[6,6-Dimethyl-2-(4-phenylazo-benzenesulfonylamino)-bicyclo[3.1.1]hept-3-yl]-hept-5-enoic acidIC503400.0 [1]
7-[6,6-Dimethyl-2-(4-phenylazo-benzoylamino)-bicyclo[3.1.1]hept-3-yl]-hept-5-enoic acidIC5010000.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-[[4-(2-Phenylethynyl)phenyl]sulfonylamino]-2-bicyclo[2.2.1]heptanyl]hept-5-enoic acidIC5010000.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-[(7-Nitrodibenzofuran-2-yl)sulfonylamino]-2-bicyclo[2.2.1]heptanyl]hept-5-enoic acidIC504500.0 [1]
7-(2-Benzoylamino-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl)-hept-5-enoic acidIC5010000.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-[(2-Methoxydibenzofuran-3-yl)sulfonylamino]-2-bicyclo[2.2.1]heptanyl]hept-5-enoic acidIC505900.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-[(4-Phenylphenyl)sulfonylamino]-2-bicyclo[2.2.1]heptanyl]hept-5-enoic acidIC505000.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-[(4-Phenoxyphenyl)sulfonylamino]-2-bicyclo[2.2.1]heptanyl]hept-5-enoic acidIC5010000.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acidIC501500.0 [1]
(Z)-7-[(1R,2R,6S,7R)-3-(4-Phenylazo-benzenesulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acidIC5010000.0 [1]
(Z)-7-[(1S,2R,3R,4R)-3-[(2-Phenyl-1H-indol-6-yl)sulfonylamino]-2-bicyclo[2.2.1]heptanyl]hept-5-enoic acidIC5010000.0 [1]
2-[[3-[2-(1,1-Diphenylethylsulfanyl)ethyl]-2-(hydroxymethyl)-1-benzofuran-7-yl]oxy]acetic acidKi530.0 [1]
4-[(1S)-1-[[5-Chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acidKi6000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Prostanoid IP receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/prostanoid-ip-receptor-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, May 10). Quest Database™ Prostanoid IP receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/prostanoid-ip-receptor-inhibitors-ic50-ki.
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