Protein-tyrosine phosphatase LC-PTP Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 5777336	IC50	1000.0 [1]
	CID 5777336	Ki	690.0 [1]
	Linoleic acid	IC50	100000.0 [1]
	Enoxolone	IC50	300000.0 [1]
	Caffeic acid	IC50	100000.0 [1]
	Estramustine phosphate	IC50	152700.0 [1]
	Celastrol	IC50	75700.0 [1]
	Imperatorin	IC50	100000.0 [1]
	Polyestradiol phosphate	IC50	300000.0 [1]
	2,3-Dihydroxypropyl decanoate	IC50	100000.0 [1]
	FlAsH	IC50	250.0 [1]
	8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid	IC50	7745.0 [1]
	Stigmasterol glucoside	IC50	82500.0 [1]
	Dotriacontanoic acid	IC50	100000.0 [1]
	cis-12-Octadecenoic acid	IC50	100000.0 [1]
	CID 25262525	IC50	32100.0 [1]
	Cefsulodin sodium salt	IC50	250000.0 [1]
	6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acid	IC50	50000.0 [1]
	2-[4-[(Z)-[5-(4-Chlorophenyl)-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acid	IC50	1300.0 [1]
	CID 71734765	IC50	3000.0 [1]
	6-(Hydroxymethyl)pyridin-3-ol	IC50	100000.0 [1]
	4-[5-[4-(4-Fluorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]-4-oxobutanoic acid	IC50	47800.0 [1]
	(9Z)-Heptadeca-1,9-dien-4,6-diyne-3,8,11-triol	IC50	100000.0 [1]
	2-[(5Z)-5-[[3-[4-[(2-Fluorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid	IC50	870.0 [1]
	6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acid	IC50	2100.0 [1]
	3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acid	IC50	3300.0 [1]
	6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acid	IC50	1900.0 [1]
	3-Chloro-N-(5-methyl-1,3-benzothiazol-2-yl)-1-benzothiophene-2-carboxamide	IC50	8000.0 [1]
	2-Hydroxy-4-[1-(cyclohexylcarbamoyl)pentyloxy]-5-[2-(trifluoromethoxy)phenylethynyl]benzoic acid	IC50	8700.0 [1]
	2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acid	IC50	50000.0 [1]
	8Z,11Z-Heptadecadienoic Acid	IC50	100000.0 [1]
	CID 1435211	IC50	40000.0 [1]
	2-(3-Cyano-5,8-dimethylquinolin-2-yl)sulfanyl-N-(2-ethyl-6-methylphenyl)acetamide	IC50	10000.0 [1]
	2-(3-Cyano-7-methoxyquinolin-2-yl)sulfanyl-N-(2,3-dimethylphenyl)acetamide	IC50	15000.0 [1]
	CID 16220825	IC50	1000000.0 [1]
	CID 16220826	IC50	1000000.0 [1]
	CID 16220827	IC50	211000.0 [1]
	CID 16221752	IC50	1000000.0 [1]
	CID 16221754	IC50	1000000.0 [1]
	CID 16221756	IC50	1000000.0 [1]
	CID 16221757	IC50	7500.0 [1]
	3-[(1-Cyclopentyltetrazol-5-yl)-piperidin-1-ylmethyl]-6-methyl-1H-quinolin-2-one	IC50	75000.0 [1]
	3-[(1-Cyclopentyltetrazol-5-yl)-(4-phenylpiperazin-1-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	75000.0 [1]
	3-[(1-Cyclopentyltetrazol-5-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-6-methyl-1H-quinolin-2-one	IC50	75000.0 [1]
	3-[[4-(1,3-Benzothiazol-2-yl)piperazin-1-yl]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	75000.0 [1]
	3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyril	IC50	20000.0 [1]
	2-[1-(4-Methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanyl-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone	IC50	18000.0 [1]
	N-(1,3-Benzodioxol-5-yl)-2-(3-cyano-7-methylquinolin-2-yl)sulfanylacetamide	IC50	12000.0 [1]
	N-(3-Chlorophenyl)-2-(3-cyano-8-methylquinolin-2-yl)sulfanylacetamide	IC50	22000.0 [1]
	2-(3-Cyano-7,8-dimethylquinolin-2-yl)sulfanyl-N-cyclohexylacetamide	IC50	8000.0 [1]
	2-(3-Cyano-7,8-dimethylquinolin-2-yl)sulfanyl-N-(3,4-dimethylphenyl)acetamide	IC50	20000.0 [1]
	2-(3-Cyano-6,8-dimethylquinolin-2-yl)sulfanyl-N-(4-ethoxyphenyl)acetamide	IC50	16000.0 [1]
	2-[(5,6-Dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide	IC50	9000.0 [1]
	2-[4-[[4-[(4-Oxalophenoxy)methyl]-3-[[4-(4-phenylphenoxy)phenyl]carbamoyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	21000.0 [1]
	2-[4-[[4-[(4-Oxalophenoxy)methyl]-3-[[4-[4-(trifluoromethylsulfanyl)phenoxy]phenyl]carbamoyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	53000.0 [1]
	2-[4-[[3-[[4-(4-Ethylphenoxy)phenyl]carbamoyl]-4-[(4-oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	52000.0 [1]
	2-[4-[[3-[[4-(4-Hexylphenoxy)phenyl]carbamoyl]-4-[(4-oxalophenoxy)methyl]phenyl]methoxy]phenyl]-2-oxoacetic acid	IC50	28000.0 [1]
	3-[1-[4-[(4-Chloronaphthalen-1-yl)amino]-4-oxobutyl]triazol-4-yl]-6-hydroxy-2-(4-methylphenyl)-1-benzofuran-5-carboxylic acid	IC50	3690.0 [1]
	6-Hydroxy-2-(4-methoxyphenyl)-3-[1-[4-(naphthalen-1-ylamino)-4-oxobutyl]triazol-4-yl]-1-benzofuran-5-carboxylic acid	IC50	3700.0 [1]
	Methyl 3-[1-[4-[(4-chloronaphthalen-1-yl)amino]-4-oxobutyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylate	IC50	32000.0 [1]
	6-Hydroxy-2-(4-methylphenyl)-3-[1-[4-(naphthalen-1-ylamino)-4-oxobutyl]triazol-4-yl]-1-benzofuran-5-carboxylic acid	IC50	4070.0 [1]
	6-Hydroxy-3-[1-[4-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-oxobutyl]triazol-4-yl]-2-(3-methylphenyl)-1-benzofuran-5-carboxylic acid	IC50	6360.0 [1]
	10Z,13Z-Nonadecadienoic acid	IC50	100000.0 [1]
	12Z,15Z-Heneicosadienoic acid	IC50	44800.0 [1]
	2-[4-[(Z)-[6-Ethoxycarbonyl-5-(3-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acid	IC50	4600.0 [1]
	2-[4-[(Z)-[5-(2-Chlorophenyl)-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]-2-methoxy-6-methylphenoxy]acetic acid	IC50	3700.0 [1]
	(18Z,21Z)-Heptacosa-18,21-dienoic acid	IC50	100000.0 [1]
	[2-Hydroxy-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropyl] dodecanoate	IC50	100000.0 [1]
	2-[(5Z)-4-Oxo-5-[[1-phenyl-3-(4-phenylmethoxyphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid	IC50	1500.0 [1]
	2-[4-[(Z)-[6-Ethoxycarbonyl-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acid	IC50	1800.0 [1]
	2-[(5Z)-5-[[3-[4-[(4-Chlorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid	IC50	620.0 [1]
	2-[(5Z)-4-Oxo-5-[[1-phenyl-3-(4-piperidin-1-ylsulfonylphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid	IC50	2400.0 [1]
	2-[(5Z)-5-[[3-[4-[(2-Chlorophenyl)methoxy]phenyl]-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid	IC50	1200.0 [1]
	Ethyl (2Z)-7-methyl-3-oxo-5-thiophen-2-yl-2-[(3,4,5-trimethoxyphenyl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate	IC50	50000.0 [1]
	Lyp-IN-1	IC50	15000.0 [1]
	3-[2-Azaspiro[5.5]undecan-2-yl-(1-propan-2-yltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one	IC50	75000.0 [1]
	N-(4-Fluoro-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine	IC50	38000.0 [1]
	6-Hydroxy-3-iodo-1-methyl-2-[3-[[2-oxo-2-(4-thiophen-3-ylanilino)acetyl]amino]phenyl]indole-5-carboxylic acid	IC50	1030.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 80 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Protein-tyrosine phosphatase LC-PTP Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 8 May. 2024, https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-lc-ptp-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 8). Quest Database™ Protein-tyrosine phosphatase LC-PTP Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/protein-tyrosine-phosphatase-lc-ptp-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan