Name: Proteinase-activated receptor 2 Inhibitors (IC50, Ki)
Creator: AAT Bioquest
License: https://www.aatbio.com/tou.html

Proteinase-activated receptor 2 Inhibitors (IC50, Ki)

Structure	Compound Name	Standard Type	Standard Values (in nM)
	N-[(2S)-3-Cyclohexyl-1-[[(2S,3S)-3-methyl-1-oxo-1-(4-phenylpiperidin-1-yl)pentan-2-yl]amino]-1-oxopropan-2-yl]-1,2-oxazole-5-carboxamide	IC50	2200.0 ^[1]
	N-[(2S)-3-Cyclohexyl-1-[[(2S,3S)-3-methyl-1-oxo-1-spiro[indene-1,4'-piperidine]-1'-ylpentan-2-yl]amino]-1-oxopropan-2-yl]-1,2-oxazole-5-carboxamide	IC50	1000.0 ^[1], 1584.89 ^[2], 3600.0 ^[3], 9600.0 ^[4]
	N-[(2S)-3-Cyclohexyl-1-[[(2S,3S)-1-[(2-methoxyphenyl)methylamino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-1,2-oxazole-5-carboxamide	IC50	400.0 ^[1], 500.0 ^[2], 1700.0 ^[3], 1900.0 ^[4]
	Tert-butyl 4-[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazine-1-carboxylate	IC50	4.2 ^[1], 4.8 ^[2], 50000.0 ^[3]
	Tert-butyl 4-[6-(4-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazine-1-carboxylate	IC50	2.0 ^[1], 5.0 ^[2], 51000.0 ^[3], 97000.0 ^[4]
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References

This online resource may be cited as follows

MLA	"Quest Database™ Proteinase-activated receptor 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 4 Jan. 2026, https://www.aatbio.com/data-sets/proteinase-activated-receptor-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2026, January 4). Quest Database™ Proteinase-activated receptor 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/proteinase-activated-receptor-2-inhibitors-ic50-ki.
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