Puromycin-sensitive aminopeptidase Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Puromycin	IC50	2450.0 [1], 9700.0 [2]
	Ubenimex	IC50	3500.0 [1]
	Tosedostat	IC50	260.0 [1]
	2-(2,6-Diethylphenyl)-4H-isoquinoline-1,3-dione	IC50	7800.0 [1]
	3-(2,6-Diethylphenyl)-1H-quinazoline-2,4-dione	IC50	3800.0 [1]
	Antaq	IC50	2900.0 [1]
	Ethyl 4-anilino-1-phenyl-2,6-dipyridin-3-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	1790.0 [1]
	(2R)-2-Amino-3-benzylsulfanyl-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]propanamide	IC50	940.0 [1]
	(2R)-2-Amino-3-benzhydrylsulfanyl-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]propanamide	IC50	7.4 [1]
	1-Methyl-3-(2,6-diethylphenyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione	IC50	3400.0 [1]
	Ethyl 4-oxo-1-phenyl-2,6-dipyridin-3-ylpiperidine-3-carboxylate	IC50	8040.0 [1]
	1-Phenyl-2,6-dipyridin-2-yl-3,6-dihydro-2H-pyridin-4-ol	IC50	36420.0 [1]
	Ethyl 4-anilino-1-phenyl-2,6-dipyridin-2-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	92510.0 [1]
	Ethyl 4-anilino-2-(4-bromophenyl)-1-phenyl-6-thiophen-2-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	80970.0 [1]
	Ethyl 4-anilino-2-(4-cyanophenyl)-1-phenyl-6-pyridin-2-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	32680.0 [1]
	Ethyl 4-(4-methylanilino)-1-(4-methylphenyl)-2-phenyl-6-pyridin-2-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	8530.0 [1]
	Ethyl 4-anilino-1-phenyl-6-pyridin-3-yl-2-(3,4,5-trimethoxyphenyl)-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	42960.0 [1]
	Ethyl 4-oxo-1-phenyl-2,6-dipyridin-2-ylpiperidine-3-carboxylate	IC50	92870.0 [1]
	1-Phenyl-2,6-dipyridin-3-yl-3,6-dihydro-2H-pyridin-4-ol	IC50	36270.0 [1]
	Ethyl 4-anilino-2-(4-chlorophenyl)-1-phenyl-6-pyridin-3-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	98190.0 [1]
	Ethyl 4-anilino-2-(4-cyanophenyl)-1-phenyl-6-pyridin-3-yl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	10180.0 [1]
	(2S)-2-Amino-3-benzylsulfanyl-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]propanamide	IC50	53000.0 [1]
	(2S)-2-Amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-tritylsulfanylpropanamide	IC50	100000.0 [1]
	(2R)-2-Amino-3-benzhydrylsulfanyl-N-(3-hydroxypropyl)propanamide	IC50	53000.0 [1]
	(2S)-2-Amino-3-benzhydrylsulfanyl-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]propanamide	IC50	4800.0 [1]
	(2R)-2-Amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-tritylsulfanylpropanamide	IC50	1400.0 [1]
	Dampaq	IC50	4600.0 [1]
	Chembl4161496	IC50	5000.0 [1]
	Methyl 4-anilino-2,6-bis(4-nitrophenyl)-1-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate	IC50	68810.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 29 ⟨⟩

---

---

References

This online tool may be cited as follows

MLA	"Quest Database™ Puromycin-sensitive aminopeptidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 9 May. 2024, https://www.aatbio.com/data-sets/puromycin-sensitive-aminopeptidase-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 9). Quest Database™ Puromycin-sensitive aminopeptidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/puromycin-sensitive-aminopeptidase-inhibitors-ic50-ki.
BibTeX	EndNote	RefMan