Rap guanine nucleotide exchange factor 3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 6077765	IC50	3200.0 [1], 10800.0 [2]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanide	IC50	2400.0 [1], 2700.0 [2]
	(2R)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbaldehyde	IC50	3300.0 [1], 4200.0 [2], 5500.0 [3]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanide	IC50	2400.0 [1]
	(1E)-N-(3-Chloroanilino)-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanide	IC50	150000.0 [1]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	5700.0 [1]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-(3-chloro-5-fluoroanilino)-2-oxoethanimidoyl cyanide	IC50	11600.0 [1]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-(3-chloro-4-fluoroanilino)-2-oxoethanimidoyl cyanide	IC50	7800.0 [1]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	9700.0 [1]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	4300.0 [1]
	(1E)-2-(5-Tert-butyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trifluoroanilino)ethanimidoyl cyanide	IC50	8900.0 [1]
	(1E)-2-(5-Cyclohexyl-1,2-oxazol-3-yl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanide	IC50	2600.0 [1]
	(1E)-2-(5-Cyclopropyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanide	IC50	4100.0 [1]
	(1E)-2-(5-Cyclohexyl-1,2-oxazol-3-yl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanide	IC50	4000.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanide	IC50	5400.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-naphthalen-2-yl-2-oxoethanimidoyl cyanide	IC50	11300.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-N-(3-chloro-4-fluoroanilino)-2-oxoethanimidoyl cyanide	IC50	12400.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-N-(3-chloro-5-fluoroanilino)-2-oxoethanimidoyl cyanide	IC50	6400.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-(3,4-dimethoxyphenyl)-2-oxoethanimidoyl cyanide	IC50	300000.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-[4-(morpholin-4-ylmethyl)phenyl]-2-oxoethanimidoyl cyanide	IC50	14600.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	6100.0 [1]
	(1E)-2-(4-Cyclohexylphenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanide	IC50	32400.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-2-oxo-N-(3,4,5-trifluoroanilino)ethanimidoyl cyanide	IC50	24400.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	5600.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-quinolin-6-ylethanimidoyl cyanide	IC50	19600.0 [1]
	(1E)-2-(4-Chlorophenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanide	IC50	300000.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	50800.0 [1]
	(1E)-2-(3-Chlorophenyl)-N-(3,5-dichloroanilino)-2-oxoethanimidoyl cyanide	IC50	300000.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-[4-(piperidin-1-ylmethyl)phenyl]ethanimidoyl cyanide	IC50	39400.0 [1]
	(1E)-2-(4-Tert-butylphenyl)-2-oxo-N-(3,4,5-trichloroanilino)ethanimidoyl cyanide	IC50	13900.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-[4-(trifluoromethoxy)phenyl]ethanimidoyl cyanide	IC50	40900.0 [1]
	(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	9000.0 [1]
	(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	10200.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-(3-chloro-4-fluoroanilino)-2-oxoethanimidoyl cyanide	IC50	8500.0 [1]
	(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	5600.0 [1]
	(1E)-N-(3-Chloroanilino)-2-[5-(furan-2-yl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	9900.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-(3-chloroanilino)-2-oxoethanimidoyl cyanide	IC50	13200.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-2-oxo-N-(3,4,5-trifluoroanilino)ethanimidoyl cyanide	IC50	13100.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-(3-chloro-5-fluoroanilino)-2-oxoethanimidoyl cyanide	IC50	18900.0 [1]
	(1E)-N-[3-Chloro-5-(trifluoromethyl)anilino]-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanide	IC50	9500.0 [1]
	(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	7300.0 [1]
	(1E)-N-(3-Chloroanilino)-2-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	38600.0 [1]
	(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-[5-(furan-2-yl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	4200.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-[3-chloro-4-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	3000.0 [1]
	(1E)-N-(3-Chloroanilino)-2-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	11400.0 [1]
	(1E)-2-[5-(4-Chlorophenyl)-1,2-oxazol-3-yl]-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	7800.0 [1]
	(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanide	IC50	7200.0 [1]
	(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	10200.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-[3-chloro-5-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	4600.0 [1]
	(1E)-2-[5-(4-Tert-butylphenyl)-1,2-oxazol-3-yl]-N-(3-chloroanilino)-2-oxoethanimidoyl cyanide	IC50	8600.0 [1]
	(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	5600.0 [1]
	(1E)-N-(3-Chloroanilino)-2-[5-(4-chlorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	77600.0 [1]
	(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-[5-(4-tert-butylphenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	11900.0 [1]
	(1E)-N-[4-Chloro-3-(trifluoromethyl)anilino]-2-oxo-2-(5-phenyl-1,2-oxazol-3-yl)ethanimidoyl cyanide	IC50	2400.0 [1]
	(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-[5-(4-chlorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	11400.0 [1]
	(1E)-N-[3-Chloro-5-(trifluoromethyl)anilino]-2-[5-(4-fluorophenyl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	12700.0 [1]
	(1E)-N-[3-Chloro-5-(trifluoromethyl)anilino]-2-[5-(furan-2-yl)-1,2-oxazol-3-yl]-2-oxoethanimidoyl cyanide	IC50	3600.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-[3,5-bis(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	6700.0 [1]
	(1E)-2-(1,2-Benzoxazol-3-yl)-N-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethanimidoyl cyanide	IC50	2700.0 [1]
	(2R)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothialdehyde	IC50	17600.0 [1]
	(2S)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbothialdehyde	IC50	100000.0 [1]
	Methyl 4-[(2E)-2-cyano-2-[(3,5-dichlorophenyl)hydrazinylidene]acetyl]benzoate	IC50	29300.0 [1]
	(1E)-N-(3,5-Dichloroanilino)-2-oxo-2-(4-phenylphenyl)ethanimidoyl cyanide	IC50	300000.0 [1]
	(1E)-N-[3,5-Bis(trifluoromethyl)anilino]-2-(5-tert-butyl-1,2-oxazol-3-yl)-2-oxoethanimidoyl cyanide	IC50	5700.0 [1]
	(2S)-5,7-Dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbaldehyde	IC50	31300.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 65 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Rap guanine nucleotide exchange factor 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 10 May. 2024, https://www.aatbio.com/data-sets/rap-guanine-nucleotide-exchange-factor-3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, May 10). Quest Database™ Rap guanine nucleotide exchange factor 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/rap-guanine-nucleotide-exchange-factor-3-inhibitors-ic50-ki.
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